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7-nitroindazole and Dyskinesia, Drug-Induced

7-nitroindazole has been researched along with Dyskinesia, Drug-Induced in 11 studies

7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
"Chronic L-DOPA pharmacotherapy in Parkinson's disease is often accompanied by the development of abnormal and excessive movements known as L-DOPA-induced dyskinesia."1.35Nitric oxide synthase inhibition attenuates L-DOPA-induced dyskinesias in a rodent model of Parkinson's disease. ( Del-Bel, EA; Echeverry, MB; Padovan-Neto, FE; Tumas, V, 2009)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's8 (72.73)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Herrero, MT1
Yuste, JE1
Cuenca-Bermejo, L1
Almela, P1
Arenas-Betancur, L1
De Pablos, V1
Gonzalez-Cuello, A1
Del Bel, E3
Navarro-Zaragoza, J1
Fernández-Villalba, E1
Padovan-Neto, FE6
Ferreira, NR1
de Oliveira-Tavares, D1
de Aguiar, D1
da Silva, CA1
Raisman-Vozari, R3
Del-Bel, E3
Szawka, RE1
da-Silva, CA4
Anselmo-Franci, J2
Romano-Dutra, AC1
Guimaraes, FS1
Cavalcanti-Kiwiatkoviski, R1
Carolino, RO1
Solís, O1
Espadas, I1
Del-Bel, EA2
Moratalla, R1
Bortolanza, M2
Cavalcanti-Kiwiatkoski, R1
Mitkovski, M1
Bariotto-Dos-Santos, KD1
Dos-Santos-Pereira, M1
Echeverry, MB1
Tumas, V2
Novaretti, N1
Del Bel, EA1
Takuma, K1
Tanaka, T1
Takahashi, T1
Hiramatsu, N1
Ota, Y1
Ago, Y1
Matsuda, T1
Araki, T1
Mizutani, H1
Matsubara, M1
Imai, Y1
Mizugaki, M1
Itoyama, Y1

Other Studies

11 other studies available for 7-nitroindazole and Dyskinesia, Drug-Induced

ArticleYear
7-Nitroindazole reduces L-DOPA-induced dyskinesias in non-human Parkinsonian primate.
    Open biology, 2023, Volume: 13, Issue:5

    Topics: Animals; Antiparkinson Agents; Dyskinesia, Drug-Induced; Levodopa; Parkinson Disease; Parkinsonian D

2023
Anti-dyskinetic effect of the neuronal nitric oxide synthase inhibitor is linked to decrease of FosB/deltaFosB expression.
    Neuroscience letters, 2013, Apr-29, Volume: 541

    Topics: Animals; Antiparkinson Agents; Corpus Striatum; Dyskinesia, Drug-Induced; Indazoles; Levodopa; Male;

2013
Counteraction by nitric oxide synthase inhibitor of neurochemical alterations of dopaminergic system in 6-OHDA-lesioned rats under L-DOPA treatment.
    Neurotoxicity research, 2014, Volume: 25, Issue:1

    Topics: Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Enzyme Inhibitor

2014
Effects of prolonged neuronal nitric oxide synthase inhibition on the development and expression of L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats.
    Neuropharmacology, 2015, Volume: 89

    Topics: Animals; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Indazoles; Levodopa; Male; Nitric Oxide Syntha

2015
Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3(-/-) aphakia mice.
    Neurobiology of disease, 2015, Volume: 73

    Topics: Animals; Antiparkinson Agents; Benserazide; Cell Count; Corpus Striatum; Disease Models, Animal; Dop

2015
Glial activation is associated with l-DOPA induced dyskinesia and blocked by a nitric oxide synthase inhibitor in a rat model of Parkinson's disease.
    Neurobiology of disease, 2015, Volume: 73

    Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dyskinesia, Drug-Induced; Indazoles; Inflamma

2015
Antidyskinetic Effect of 7-Nitroindazole and Sodium Nitroprusside Associated with Amantadine in a Rat Model of Parkinson's Disease.
    Neurotoxicity research, 2016, Volume: 30, Issue:1

    Topics: Amantadine; Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Dyskinesia,

2016
Nitric oxide synthase inhibition attenuates L-DOPA-induced dyskinesias in a rodent model of Parkinson's disease.
    Neuroscience, 2009, Mar-31, Volume: 159, Issue:3

    Topics: Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; En

2009
Lack of tolerance for the anti-dyskinetic effects of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2010, Volume: 43, Issue:11

    Topics: Animals; Anti-Dyskinesia Agents; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced;

2010
Neuronal nitric oxide synthase inhibition attenuates the development of L-DOPA-induced dyskinesia in hemi-Parkinsonian rats.
    European journal of pharmacology, 2012, May-15, Volume: 683, Issue:1-3

    Topics: Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Dopamine and cAMP-Regulated Phosphoprotein 32

2012
Nitric oxide synthase inhibitors cause motor deficits in mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2001, Volume: 11, Issue:2

    Topics: Animals; Brain Chemistry; Catalepsy; Dopamine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Enzym

2001