7-nitroindazole has been researched along with Chronic Disease in 6 studies
7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the effects of chronic treatment with the preferential nNOS inhibitor 7-nitroindazole (7-NI) with those evoked by the conventional antidepressant fluoxetine on alterations that are considered as markers of depression (immobility in the forced swimming test, FST, decreased body weight gain and increased plasma corticosterone concentration) and cardiovascular changes caused by CVS." | 7.81 | Effects of nitric oxide synthesis inhibitor or fluoxetine treatment on depression-like state and cardiovascular changes induced by chronic variable stress in rats. ( Almeida, J; Crestani, CC; Duarte, JO; Oliveira, LA, 2015) |
| "Treatment with methionine (0." | 5.35 | Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid. ( Bonaventura, D; de Oliveira, AM; Tirapelli, CR, 2009) |
| " We compared the effects of chronic treatment with the preferential nNOS inhibitor 7-nitroindazole (7-NI) with those evoked by the conventional antidepressant fluoxetine on alterations that are considered as markers of depression (immobility in the forced swimming test, FST, decreased body weight gain and increased plasma corticosterone concentration) and cardiovascular changes caused by CVS." | 3.81 | Effects of nitric oxide synthesis inhibitor or fluoxetine treatment on depression-like state and cardiovascular changes induced by chronic variable stress in rats. ( Almeida, J; Crestani, CC; Duarte, JO; Oliveira, LA, 2015) |
| "Treatment with methionine (0." | 1.35 | Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid. ( Bonaventura, D; de Oliveira, AM; Tirapelli, CR, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almeida, J | 1 |
| Duarte, JO | 1 |
| Oliveira, LA | 1 |
| Crestani, CC | 1 |
| El-faramawy, YA | 1 |
| El-banouby, MH | 1 |
| Sergeev, P | 1 |
| Mortagy, AK | 1 |
| Amer, MS | 1 |
| Abdel-tawab, AM | 1 |
| Bonaventura, D | 1 |
| Tirapelli, CR | 1 |
| de Oliveira, AM | 1 |
| Tesser-Viscaíno, SA | 1 |
| Denadai-Souza, A | 1 |
| Teixeira, SA | 1 |
| Ervolino, E | 1 |
| Cruz-Rizzolo, RJ | 1 |
| Costa, SK | 1 |
| Muscará, MN | 1 |
| Casatti, CA | 1 |
| Fike, CD | 1 |
| Aschner, JL | 1 |
| Zhang, Y | 1 |
| Kaplowitz, MR | 1 |
| Hao, JX | 1 |
| Xu, XJ | 1 |
6 other studies available for 7-nitroindazole and Chronic Disease
| Article | Year |
|---|---|
Effects of nitric oxide synthesis inhibitor or fluoxetine treatment on depression-like state and cardiovascular changes induced by chronic variable stress in rats.
Topics: Animals; Antidepressive Agents; Autonomic Nervous System; Baroreflex; Behavior, Animal; Cardiovascul | 2015 |
Changes in glutamate decarboxylase enzyme activity and tau-protein phosphorylation in the hippocampus of old rats exposed to chronic mild stress: reversal with the neuronal nitric oxide synthase inhibitor 7-nitroindazole.
Topics: Aging; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Chronic Disease; Enzyme Inh | 2009 |
Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid.
Topics: Animals; Bradykinin; Cardiovascular Agents; Carotid Arteries; Chronic Disease; Enzyme Inhibitors; Hy | 2009 |
Putative antinociceptive action of nitric oxide in the caudal part of the spinal trigeminal nucleus during chronic carrageenan-induced arthritis in the rat temporomandibular joint.
Topics: Animals; Arthralgia; Arthritis, Experimental; Carrageenan; Chronic Disease; Disease Models, Animal; | 2009 |
Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets.
Topics: Animals; Animals, Newborn; Caveolin 1; Caveolins; Chronic Disease; Enzyme Inhibitors; Guanidines; HS | 2004 |
Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered nitric oxide synthase inhibitors.
Topics: Adrenergic Agonists; Analgesics; Animals; Arousal; Blood Pressure; Chronic Disease; Dose-Response Re | 1996 |