Page last updated: 2024-10-21

7-nitroindazole and Anoxia, Brain

7-nitroindazole has been researched along with Anoxia, Brain in 9 studies

7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure

Research Excerpts

ExcerptRelevanceReference
"Previous studies have shown that cerebral hypoxia results in increased activity of caspase-9, a key initiator of programmed cell death."1.33Effect of neuronal nitric oxide synthase inhibition on caspase-9 activity during hypoxia in the cerebral cortex of newborn piglets. ( Delivoria-Papadopoulos, M; Mishra, OP, 2006)
"Indomethacin pretreatment inhibited increases in mRNA and protein for PGHS-2 after ischemia, while 7-NI had little effect on increases in PGHS-2 immunoreactivity."1.30Effects of anoxic stress on prostaglandin H synthase isoforms in piglet brain. ( Bari, F; Beasley, TC; Busija, DW; Dégì, R; Louis, TM; Thore, C; Thrikawala, N, 1998)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's6 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mishra, OP3
Delivoria-Papadopoulos, M3
Mishra, R1
Ashraf, QM2
Zubrow, AB1
Jiang, MH1
Hada, J1
Izumi, Y1
Benz, AM1
Clifford, DB1
Zorumski, CF1
Higuchi, Y1
Hattori, H1
Kume, T1
Tsuji, M1
Akaike, A1
Furusho, K1
Dégì, R1
Bari, F1
Thrikawala, N1
Beasley, TC1
Thore, C1
Louis, TM1
Busija, DW1
Hudetz, AG1
Wood, JD1
Kampine, JP1
Muramatsu, K1
Sheldon, RA1
Black, SM1
Täuber, M1
Ferriero, DM1

Other Studies

9 other studies available for 7-nitroindazole and Anoxia, Brain

ArticleYear
Effect of neuronal nitric oxide synthase inhibition on caspase-9 activity during hypoxia in the cerebral cortex of newborn piglets.
    Neuroscience letters, 2006, Jun-19, Volume: 401, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Apoptosis; Brain; Brain Chemistry; Caspase 9; Cas

2006
Nitric oxide-mediated mechanism of neuronal nitric oxide synthase and inducible nitric oxide synthase expression during hypoxia in the cerebral cortex of newborn piglets.
    Neuroscience, 2006, Jul-07, Volume: 140, Issue:3

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cell Death; Cerebral Cortex; Cerebral Infarction;

2006
Effect of nitric oxide synthase inhibition during post-hypoxic reoxygenation on Bax and Bcl-2 protein expression and DNA fragmentation in neuronal nuclei of newborn piglets.
    Brain research, 2006, Jul-26, Volume: 1101, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; bcl-2-Associated X Protein; Blotting, Southern; Blo

2006
Early and sharp nitric oxide production and anoxic depolarization in the rat hippocampus during transient forebrain ischemia.
    European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2

    Topics: Animals; Benzoates; Blood Pressure; Hippocampus; Hypoxia, Brain; Imidazoles; Indazoles; Ischemic Att

2007
Nitric oxide inhibitors attenuate ischemic degeneration in the CA1 region of rat hippocampal slices.
    Neuroscience letters, 1996, Jun-07, Volume: 210, Issue:3

    Topics: Animals; Brain Ischemia; Enzyme Inhibitors; Glucose; Hippocampus; Hypoxia, Brain; Indazoles; N-Methy

1996
Increase in nitric oxide in the hypoxic-ischemic neonatal rat brain and suppression by 7-nitroindazole and aminoguanidine.
    European journal of pharmacology, 1998, Jan-19, Volume: 342, Issue:1

    Topics: Animals; Animals, Newborn; Brain Chemistry; Brain Ischemia; Enzyme Induction; Enzyme Inhibitors; Gua

1998
Effects of anoxic stress on prostaglandin H synthase isoforms in piglet brain.
    Brain research. Developmental brain research, 1998, May-15, Volume: 107, Issue:2

    Topics: Animals; Body Temperature; Brain; Cerebral Cortex; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fem

1998
7-Nitroindazole impedes erythrocyte flow response to isovolemic hemodilution in the cerebral capillary circulation.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:2

    Topics: Anemia; Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Cerebrovascular Circulation; Enzy

2000
Nitric oxide synthase activity and inhibition after neonatal hypoxia ischemia in the mouse brain.
    Brain research. Developmental brain research, 2000, Oct-28, Volume: 123, Issue:2

    Topics: Animals; Animals, Newborn; Blotting, Western; Brain; Brain Ischemia; Enzyme Inhibitors; Female; Hypo

2000