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7-nitroindazole and Acute Post-Traumatic Stress Disorder

7-nitroindazole has been researched along with Acute Post-Traumatic Stress Disorder in 3 studies

7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure

Research Excerpts

ExcerptRelevanceReference
" Therefore, in this study, we combined subchronic fluoxetine (Flx) with 7-nitroindazole (NI), a selective nNOS inhibitor, and evaluated their efficacy against anxiety-related behavior in an animal model of PTSD."4.31Neuronal nitric oxide synthase inhibition accelerated the removal of fluoxetine's anxiogenic activity in an animal model of PTSD. ( Chamanara, M; Dehpour, AR; Fekrvand, S; Foroutani, L; Hemmati, S; Hosseini, Y; Nassireslami, E; Sadeghi, MA; Yousefi Zoshk, M; Yousefi-Manesh, H, 2023)
"Post-traumatic stress disorder (PTSD) may be associated with shrinkage of the hippocampus, with glutamate release causally related to these events."1.33Involvement of the NMDA receptor, NO-cyclic GMP and nuclear factor K-beta in an animal model of repeated trauma. ( Bothma, T; Harvey, BH; Nel, A; Stein, DJ; Wegener, G, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Sadeghi, MA1
Hemmati, S1
Yousefi-Manesh, H1
Fekrvand, S1
Foroutani, L1
Nassireslami, E1
Yousefi Zoshk, M1
Hosseini, Y1
Dehpour, AR1
Chamanara, M1
Harvey, BH2
Oosthuizen, F1
Brand, L1
Wegener, G2
Stein, DJ2
Bothma, T1
Nel, A1

Other Studies

3 other studies available for 7-nitroindazole and Acute Post-Traumatic Stress Disorder

ArticleYear
Neuronal nitric oxide synthase inhibition accelerated the removal of fluoxetine's anxiogenic activity in an animal model of PTSD.
    Behavioural brain research, 2023, 02-02, Volume: 437

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inh

2023
Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus.
    Psychopharmacology, 2004, Volume: 175, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Corticosterone; Electrochemistry; Enzyme Inhibitors;

2004
Involvement of the NMDA receptor, NO-cyclic GMP and nuclear factor K-beta in an animal model of repeated trauma.
    Human psychopharmacology, 2005, Volume: 20, Issue:5

    Topics: Animals; Cyclic GMP; Disease Models, Animal; Hippocampus; Indazoles; Male; NF-kappa B; Nitric Oxide;

2005