7-methylguanosine and Arthritis--Rheumatoid

7-methylguanosine has been researched along with Arthritis--Rheumatoid* in 1 studies

Other Studies

1 other study(ies) available for 7-methylguanosine and Arthritis--Rheumatoid

ArticleYear
Relationship between urinary excretion of modified nucleosides and rheumatoid arthritis process.
    British journal of rheumatology, 1997, Volume: 36, Issue:9

    The levels of the five methylated nucleosides pseudouridine (psi-Urd), 1-methyladenosine (1-MeAdo), 4 acetylcytidine (4-AcCyd), 1 methylinosine (1-Melno) and 7 methylguanosine (7-MeGuo) resulting from RNA degradation were examined in the urine of rheumatoid arthritis (RA) patients. Of these five, 1-MeAdo and psi-Urd were correlated with the active phase of the disease, while two others (4-AcCyd and 1-Melno), which require further evaluation, appeared to be linked to the prognosis of the disease. As RNA turnover is closely associated with cell proliferation, including that of lymphocytes in RA, there may be a hitherto unsuspected benefit in measuring 1-MeAdo and psi-Urd as biochemical markers of RA disease activity.

    Topics: Adenosine; Aged; Arthritis, Rheumatoid; Biomarkers; Cytidine; Female; Follow-Up Studies; Guanosine; Humans; Inosine; Male; Middle Aged; Nucleosides; Pseudouridine; RNA Caps; RNA, Ribosomal; RNA, Transfer

1997