7-ketocholesterol has been researched along with Inflammation in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 15 (60.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Chen, B; Chen, X; Liu, Z; Pan, N; Wu, J; Zhang, J | 1 |
| Akita, H; Baba, I; Hashimoto, Y; Ichi, I; Katsuki, S; Kawahara, T; Koga, JI; Matoba, T; Tsutsui, H; Uchikawa, T; Yamasaki, R | 1 |
| Larráyoz, IM; Pariente, A; Peláez, R; Pérez-Sala, Á | 1 |
| Gu, Q; Qiu, Q; Wu, X; Xie, L; Yang, C; Yin, L | 1 |
| Calle, P; Hotter, G; Muñoz, A; Sola, A | 1 |
| Arumugam, M; Duraisamy, P; Krishnan, M; Manikandan, B; Martin, LC; Raman, T; Ramar, M; Ravi, S; Sundaram, J | 1 |
| Badreddine, I; Boulekbache-Makhlouf, L; Brahmi, F; Lizard, G; Madani, K; Meddeb, W; Namsi, A; Nasser, B; Nury, T; Rezig, L; Sassi, K; Sghaier, R; Vejux, A; Vervandier-Fasseur, D; Yammine, A; Zarrouk, A | 1 |
| Amaral, J; Campos, MM; Chou, J; Lee, JW; Rodríguez, IR | 1 |
| Alegría, A; Alemany, L; Barberá, R; Laparra, JM | 1 |
| Businaro, R; Buttari, B; D'Arcangelo, D; Facchiano, F; Iuliano, L; Profumo, E; Riganò, R; Rossi, S; Segoni, L | 1 |
| Businaro, R; Buttari, B; D'Arcangelo, D; Facchiano, F; Iuliano, L; Profumo, E; Riganò, R; Rossi, S; Saso, L; Segoni, L | 1 |
| Amaral, J; Huang, JD; Lee, JW; Rodriguez, IR | 1 |
| Biasi, F; Cabboi, B; Calfapietra, S; Deiana, M; Gamba, P; Gargiulo, S; Guina, T; Leonarduzzi, G; Maina, M; Poli, G; Testa, G; Tuberoso, CI | 1 |
| Caccia, C; Debbabi, M; Fromont, A; Leoni, V; Lizard, G; Moreau, T; Nury, T; Sghaier, R; Vejux, A; Zarrouk, A | 1 |
| Hitsumoto, T; Iizuka, T; Shirai, K; Takahashi, M | 1 |
| Larrayoz, IM; Rodríguez, IR | 1 |
| Amaral, J; Huang, JD; Larrayoz, IM; Lee, JW; Rodriguez, IR | 1 |
| Olkkonen, VM | 1 |
| Katada, K; Kuroda, M; Manabe, H; Naito, Y; Nakabe, N; Shimozawa, M; Uchiyama, K; Yoshida, N; Yoshikawa, T | 1 |
| Biro, A; Boaz, M; Friedman, V; Gafter, U; Gvirtz, G; Himmelfarb, J; Iuliano, L; Matas, Z; McMonagle, E; Micheletta, F; Natoli, S; Sabo, G; Smetana, S; Weinstein, T | 1 |
| Ichikawa, H; Katada, K; Kokura, S; Kon, T; Manabe, H; Naito, Y; Nakabe, N; Shimozawa, M; Yoshida, N; Yoshikawa, T | 1 |
| Acar, N; Bretillon, L; Bron, A; Buteau, B; Cabaret, S; Creuzot-Garcher, C; Joffre, C; Leclère, L; Lizard, G; Malvitte, L; Martine, L | 1 |
| Dushkin, MI; Grebenshchikov, AIu; Safina, AF; Shvarts, IaSh; Vereshchagin, EI | 1 |
| Gaspari, AA; Rietschel, RL | 1 |
5 review(s) available for 7-ketocholesterol and Inflammation
| Article | Year |
|---|---|
Inflammatory and cell death mechanisms induced by 7-ketocholesterol in the retina. Implications for age-related macular degeneration.
Topics: Animals; Cell Death; Enzyme Inhibitors; Humans; Inflammation; Ketocholesterols; Macular Degeneration; Oxidation-Reduction; Retina; Retinal Pigment Epithelium; Retinitis | 2019 |
An insight on 7- ketocholesterol mediated inflammation in atherosclerosis and potential therapeutics.
Topics: Animals; Atherosclerosis; Enzyme Inhibitors; Humans; Inflammation; Ketocholesterols | 2021 |
Prevention of 7-ketocholesterol-induced side effects by natural compounds.
Topics: Antioxidants; Fatty Acids; Humans; Inflammation; Ketocholesterols; Noncommunicable Diseases; Oxidation-Reduction; Oxidative Stress; Polyphenols; Tocopherols | 2019 |
Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration.
Topics: Animals; Cell Death; Cholesterol; Humans; Inflammation; Ketocholesterols; Macular Degeneration; Oxidation-Reduction; Retina | 2010 |
Macrophage oxysterols and their binding proteins: roles in atherosclerosis.
Topics: Animals; Apoptosis; Atherosclerosis; Cell Survival; Cytoplasm; Humans; Hydroxycholesterols; Inflammation; Ketocholesterols; Lipid Metabolism; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; Plaque, Atherosclerotic; Receptors, Steroid; Signal Transduction | 2012 |
1 trial(s) available for 7-ketocholesterol and Inflammation
| Article | Year |
|---|---|
Baseline oxysterols and other markers of oxidative stress, inflammation and malnutrition in the vitamin e and intima media thickness progression in end-stage renal disease (VIPER) cohort.
Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Hydroxycholesterols; Inflammation; Ketocholesterols; Kidney Failure, Chronic; Male; Malnutrition; Middle Aged; Oxidative Stress; Renal Dialysis; Tunica Media; Vitamin E | 2005 |
19 other study(ies) available for 7-ketocholesterol and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
3β-Hydroxycholest-5-en-7-one from seahorse alleviates lipopolysaccharide-induced inflammatory responses by downregulating miR-98-5p.
Topics: 3' Untranslated Regions; Animals; Cholestenones; Down-Regulation; Genes, Reporter; Inflammation; Lentivirus; Lipopolysaccharides; Luciferases; Male; Mice; Mice, Inbred BALB C; MicroRNAs; RAW 264.7 Cells; Reproducibility of Results; Smegmamorpha | 2020 |
Dietary 7-ketocholesterol exacerbates myocardial ischemia-reperfusion injury in mice through monocyte/macrophage-mediated inflammation.
Topics: Animals; Diet; Endoplasmic Reticulum Stress; Inflammation; Ketocholesterols; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Myocardial Reperfusion Injury; Reperfusion Injury | 2022 |
7-Ketocholesterol disturbs RPE cells phagocytosis of the outer segment of photoreceptor and induces inflammation through ERK signaling pathway.
Topics: Animals; Blotting, Western; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Inflammation; Ketocholesterols; Macular Degeneration; Male; Microscopy, Electron, Transmission; Phagocytosis; Rats; Rats, Sprague-Dawley; Retinal Photoreceptor Cell Outer Segment; Retinal Pigment Epithelium; RNA; Signal Transduction | 2019 |
CPT1a gene expression reverses the inflammatory and anti-phagocytic effect of 7-ketocholesterol in RAW264.7 macrophages.
Topics: Animals; Carnitine O-Palmitoyltransferase; Down-Regulation; Gene Expression; Gene Knockdown Techniques; Inflammation; Ketocholesterols; Macrophage Activation; Macrophages; Mice; Phagocytosis; RAW 264.7 Cells; Transfection | 2019 |
7-Ketocholesterol induces inflammation and angiogenesis in vivo: a novel rat model.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aqueous Humor; Corneal Neovascularization; Disease Models, Animal; Dose-Response Relationship, Drug; Immunohistochemistry; Inflammation; Ketocholesterols; Macrophages; Male; Prostheses and Implants; Protein Transport; Rats; Vascular Endothelial Growth Factor A | 2013 |
Relative expression of cholesterol transport-related proteins and inflammation markers through the induction of 7-ketosterol-mediated stress in Caco-2 cells.
Topics: Acetyl-CoA C-Acetyltransferase; Acyl Coenzyme A; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP-Binding Cassette Transporters; Biological Transport; Biomarkers; Bradykinin; Caco-2 Cells; Down-Regulation; Humans; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-8; Ketocholesterols; Lipoproteins; Membrane Proteins; Membrane Transport Proteins; RNA, Messenger; Stigmasterol; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
7-Oxo-cholesterol potentiates pro-inflammatory signaling in human M1 and M2 macrophages.
Topics: Cell Hypoxia; Cell Polarity; Cell Survival; Cytokines; Endocytosis; Granulocyte Colony-Stimulating Factor; Humans; Inflammation; Ketocholesterols; Macrophages; Matrix Metalloproteinase 9; Vascular Endothelial Growth Factor A | 2013 |
Resveratrol counteracts inflammation in human M1 and M2 macrophages upon challenge with 7-oxo-cholesterol: potential therapeutic implications in atherosclerosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Cells, Cultured; Chemokines; Cytokines; Down-Regulation; Endocytosis; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Ketocholesterols; Lipopolysaccharide Receptors; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocytes; NF-kappa B; Receptors, IgG; Resveratrol; Stilbenes; Up-Regulation | 2014 |
7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo.
Topics: Animals; Cell Death; Cell Line; Chromones; Cyclopropanes; Endoplasmic Reticulum Stress; Enzyme Activation; Extracellular Space; Fatty Acids, Monounsaturated; Humans; Inflammasomes; Inflammation; Ketocholesterols; Morpholines; NF-kappa B; Phosphorylation; Protein Kinases; Rats; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Toll-Like Receptor 4 | 2014 |
The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics.
Topics: Caco-2 Cells; Caffeic Acids; Cell Survival; Cholesterol; Epithelial Cells; Humans; Hydroxycholesterols; Inflammation; Interleukin-8; Intestinal Mucosa; Intestines; Ketocholesterols; NADPH Oxidase 1; NADPH Oxidases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Reactive Oxygen Species; Signal Transduction; Up-Regulation; Vitis; Wine | 2015 |
Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, chole
Topics: Adenosine Triphosphate; alpha-Tocopherol; Animals; Cell Nucleus; Cholesterol; Citric Acid Cycle; Fatty Acids, Unsaturated; Flow Cytometry; Inflammation; Ketocholesterols; L-Lactate Dehydrogenase; Lipid Peroxidation; Lipids; Mass Spectrometry; Membrane Potential, Mitochondrial; Mice; Mitochondria; Multiple Sclerosis; NAD; Oligodendroglia; Oxidation-Reduction; Oxidative Stress; Oxysterols; Reactive Oxygen Species | 2017 |
Clinical significance of serum 7-ketocholesterol concentrations in the progression of coronary atherosclerosis.
Topics: Aged; Angina Pectoris; C-Reactive Protein; Case-Control Studies; Coronary Artery Disease; Disease Progression; Female; Humans; Inflammation; Ketocholesterols; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction | 2009 |
Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization.
Topics: Animals; Cells, Cultured; Choroidal Neovascularization; Cyclopropanes; Cytokines; Dose-Response Relationship, Drug; Drug Antagonism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Fatty Acids; Fatty Acids, Monounsaturated; Gene Expression; Heat-Shock Proteins; Humans; Immunoblotting; Inflammation; Inflammation Mediators; Ketocholesterols; Lasers; Male; Rats; Rats, Inbred BN; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor CHOP; Vascular Endothelial Growth Factor A | 2012 |
The inhibitory effect of alacepril, an angiotensin-converting enzyme inhibitor, on endothelial inflammatory response induced by oxysterol and TNF-alpha.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cell Adhesion; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Inflammation; Intercellular Adhesion Molecule-1; Ketocholesterols; Monocytes; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2004 |
Azelnidipine, a new calcium channel blocker, inhibits endothelial inflammatory response by reducing intracellular levels of reactive oxygen species.
Topics: Aorta; Azetidinecarboxylic Acid; Biphenyl Compounds; Calcium Channel Blockers; Cell Adhesion; Cell Membrane; Cyclic N-Oxides; Dihydropyridines; Dose-Response Relationship, Drug; Endothelial Cells; Fluoresceins; Free Radical Scavengers; Gene Expression Regulation; Humans; Hydrazines; Indicators and Reagents; Inflammation; Ketocholesterols; Monocytes; NF-kappa B p50 Subunit; Nifedipine; Picrates; Protein Transport; Reactive Oxygen Species; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha; U937 Cells; Vascular Cell Adhesion Molecule-1 | 2006 |
Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.
Topics: Animals; Chromatography, Gas; Enzyme-Linked Immunosorbent Assay; Fluoresceins; Fluorescent Dyes; Hydroxycholesterols; Inflammation; Interleukin-8; Ketocholesterols; Mitochondria; Oxidative Stress; Pigment Epithelium of Eye; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine | 2007 |
[Effects of hydroxysterols on expression of inflammatory cytokine genes and their level in macrophages tolerant to endotoxin].
Topics: Animals; Cells, Cultured; Gene Expression; Hydroxycholesterols; Inflammation; Interleukin-1; Ketocholesterols; Lipopolysaccharides; Macrophages, Peritoneal; Male; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha | 1999 |
Anti-inflammatory properties of an oxidized sterol.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cantharidin; Cholesterol; Croton Oil; Dose-Response Relationship, Drug; Female; Hydrocortisone; Inflammation; Ketocholesterols; Mice | 1985 |