Page last updated: 2024-08-26

7-ketocholesterol and Atherosclerosis

7-ketocholesterol has been researched along with Atherosclerosis in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (29.17)29.6817
2010's15 (62.50)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Buttari, B; Profumo, E; Riganò, R; Saha, S; Saso, L; Togna, AR1
Arumugam, M; Duraisamy, P; Krishnan, M; Manikandan, B; Martin, LC; Raman, T; Ramar, M; Ravi, S; Sundaram, J1
Tabas, I; Tall, AR; Wang, N; Wang, W; Wang, Y1
He, C; Le, YZ; Li, H; Okon, I; Wang, Q; Xie, Z; Zhang, W; Zhu, H1
Chen, W; Fu, X; Huang, X; Li, P; Xia, M1
Businaro, R; Buttari, B; D'Arcangelo, D; Facchiano, F; Iuliano, L; Profumo, E; Riganò, R; Rossi, S; Saso, L; Segoni, L1
Klusonova, P; Odermatt, A1
Chen, LC; Gopalakrishnan, B; Harkema, JR; Maiseyeu, A; Rajagopalan, S; Rao, X; Sun, Q; Villamena, FA; Zhong, J1
Ahn, YT; An, WG; Chun, W; Kim, JM; Kim, K; Lee, C; Lee, CW; Son, Y1
Geng, YJ; Rosales, C; Tang, D1
Li, PL; Li, XX; Wang, L; Wang, M; Xu, M; Zhang, Y1
Deleanu, M; Sanda, GM; Sima, AV; Simionescu, M; Stancu, CS; Toma, L1
Alkazemi, D; Egeland, G; Kubow, S; Meltzer, S; Vaya, J1
Augé, N; Bando, Y; Marachet, MA; Muller, C; Nègre-Salvayre, A; Salvayre, R; Sanson, M; Sawa, Y; Thiers, JC; Vindis, C; Zarkovic, K1
Chang, BH; Goo, YH; Paul, A; Son, SH1
Jang, H; Kim, K; Kim, S; Lee, SA; Rhim, BY; Son, Y1
Olkkonen, VM1
Allegra, M; Attanzio, A; Gentile, C; Livrea, MA; Tesoriere, L1
Carson, NL; Chen, J; García, RA; Gargalovic, PS; Gordon, DA; Guan, B; Harrity, TW; He, A; Hellings, SE; Langish, RA; Lupisella, JA; Ostrowski, J; Psaltis, GC; Robl, JA; Ryan, CS; Search, DJ; Shipkova, PA; Taylor, JR; Truong, A; Watson, LM; Yan, M; Yang, R; Yang, WP; Zhang, R1
Miyashita, Y; Ohtsuka, M; Shirai, K1
Rittmann, BE; Schloendorn, J1
Guo, Z; Ran, Q; Richardson, A; Roberts, LJ; Sharan, C; Wu, D; Yang, H; Zhou, L1
Kazlauskas, A; Romeo, GR1
Boulares, AH; Catling, A; Hans, CP; Naura, AS; Zerfaoui, M1

Reviews

4 review(s) available for 7-ketocholesterol and Atherosclerosis

ArticleYear
An insight on 7- ketocholesterol mediated inflammation in atherosclerosis and potential therapeutics.
    Steroids, 2021, Volume: 172

    Topics: Animals; Atherosclerosis; Enzyme Inhibitors; Humans; Inflammation; Ketocholesterols

2021
11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 151

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Atherosclerosis; Bile Acids and Salts; Glucocorticoids; Humans; Ketocholesterols

2015
Macrophage oxysterols and their binding proteins: roles in atherosclerosis.
    Current opinion in lipidology, 2012, Volume: 23, Issue:5

    Topics: Animals; Apoptosis; Atherosclerosis; Cell Survival; Cytoplasm; Humans; Hydroxycholesterols; Inflammation; Ketocholesterols; Lipid Metabolism; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; Plaque, Atherosclerotic; Receptors, Steroid; Signal Transduction

2012
Engineering away lysosomal junk: medical bioremediation.
    Rejuvenation research, 2007, Volume: 10, Issue:3

    Topics: Atherosclerosis; Biodegradation, Environmental; Foam Cells; Genetic Engineering; Hydrocarbons; Ketocholesterols; Linoleic Acid; Longevity; Lysosomes; Metabolism; Models, Chemical; Nocardia; Petroleum

2007

Other Studies

20 other study(ies) available for 7-ketocholesterol and Atherosclerosis

ArticleYear
Lupeol Counteracts the Proinflammatory Signalling Triggered in Macrophages by 7-Keto-Cholesterol: New Perspectives in the Therapy of Atherosclerosis.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Anti-Inflammatory Agents; Atherosclerosis; Autophagy; CD36 Antigens; Endocytosis; HLA-DR Antigens; Humans; Interleukin-12; Interleukin-1beta; Ketocholesterols; Lipid Metabolism; Macrophages; Microtubule-Associated Proteins; Pentacyclic Triterpenes; Reactive Oxygen Species; Sequestosome-1 Protein; Signal Transduction; Up-Regulation

2020
Mitochondrial Oxidative Stress Promotes Atherosclerosis and Neutrophil Extracellular Traps in Aged Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:8

    Topics: Age Factors; Aging; Animals; Atherosclerosis; Bone Marrow Transplantation; Catalase; Cells, Cultured; Diet, Western; Disease Models, Animal; Extracellular Traps; Genetic Predisposition to Disease; Humans; Ketocholesterols; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Neutrophils; Oxidative Stress; Phenotype; Plaque, Atherosclerotic; Receptors, LDL

2017
7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B.
    The American journal of pathology, 2013, Volume: 183, Issue:2

    Topics: Animals; Aorta; Apoptosis; Atherosclerosis; Autophagy; Autophagy-Related Proteins; Cardiovascular Agents; Cell Death; Cells, Cultured; Cysteine Endopeptidases; Enzyme Inhibitors; Free Radical Scavengers; Humans; Hydrogen Peroxide; Ketocholesterols; Male; Mice; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Sirolimus; Up-Regulation

2013
7-Ketocholesterol inhibits isocitrate dehydrogenase 2 expression and impairs endothelial function via microRNA-144.
    Free radical biology & medicine, 2014, Volume: 71

    Topics: 3' Untranslated Regions; Animals; Aorta; Argonaute Proteins; Atherosclerosis; Cattle; Endothelial Cells; Eukaryotic Initiation Factors; Gene Expression Regulation; Glutathione; Humans; Isocitrate Dehydrogenase; Ketocholesterols; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Mitochondria; NADP; Oxidation-Reduction; RNA, Messenger; Signal Transduction

2014
Resveratrol counteracts inflammation in human M1 and M2 macrophages upon challenge with 7-oxo-cholesterol: potential therapeutic implications in atherosclerosis.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Cells, Cultured; Chemokines; Cytokines; Down-Regulation; Endocytosis; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Ketocholesterols; Lipopolysaccharide Receptors; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocytes; NF-kappa B; Receptors, IgG; Resveratrol; Stilbenes; Up-Regulation

2014
CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure.
    Circulation research, 2014, Oct-10, Volume: 115, Issue:9

    Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Biological Transport; CD36 Antigens; Disease Models, Animal; Disease Progression; Foam Cells; Human Umbilical Vein Endothelial Cells; Humans; Inhalation Exposure; Ketocholesterols; Macrophages; Male; Mice; Mice, Knockout; Oxidation-Reduction; Particle Size; Particulate Matter; Plaque, Atherosclerotic; Receptors, LDL; Time Factors

2014
7-Ketocholesterol induces the reduction of KCNMB1 in atherosclerotic blood vessels.
    Biochemical and biophysical research communications, 2015, Feb-13, Volume: 457, Issue:3

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Down-Regulation; Humans; Hypertension; Ketocholesterols; Large-Conductance Calcium-Activated Potassium Channel beta Subunits; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Receptors, Aryl Hydrocarbon; Signal Transduction

2015
CD1d serves as a surface receptor for oxidized cholesterol induction of peroxisome proliferator-activated receptor-γ.
    Atherosclerosis, 2015, Volume: 239, Issue:1

    Topics: Animals; Antigens, CD1d; Atherosclerosis; Cell Membrane; Cholesterol; DNA Primers; HEK293 Cells; Humans; Hydroxycholesterols; Immunoglobulin G; Ketocholesterols; Lipids; Macrophages; Mice; Mice, Knockout; Microscopy, Fluorescence; Oxygen; PPAR gamma; Protein Binding; Sterols

2015
Contribution of Nrf2 to Atherogenic Phenotype Switching of Coronary Arterial Smooth Muscle Cells Lacking CD38 Gene.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 37, Issue:2

    Topics: ADP-ribosyl Cyclase 1; Animals; Atherosclerosis; Calcium; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Coronary Vessels; Female; Gene Expression Regulation; Ketocholesterols; Male; Membrane Glycoproteins; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Oxidative Stress

2015
Oxidized LDL-Exposed Human Macrophages Display Increased MMP-9 Expression and Secretion Mediated by Endoplasmic Reticulum Stress.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:4

    Topics: Acetophenones; Atherosclerosis; Cell Line; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Gene Expression; Humans; Ketocholesterols; Lipoproteins, LDL; Macrophages; Matrix Metalloproteinase 9; NADPH Oxidases; Reactive Oxygen Species; RNA, Messenger; Toll-Like Receptor 4; Tunicamycin

2017
Oxysterol as a marker of atherogenic dyslipidemia in adolescence.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:11

    Topics: Adolescent; Apolipoproteins B; Atherosclerosis; Body Mass Index; Cross-Sectional Studies; Diabetes, Gestational; Dyslipidemias; Female; Humans; Hydroxycholesterols; Insulin; Ketocholesterols; Pregnancy

2008
Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression.
    Circulation research, 2009, Feb-13, Volume: 104, Issue:3

    Topics: Acetylcysteine; Aldehydes; Apoptosis; Atherosclerosis; Biomarkers; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endothelial Cells; Enzyme Inhibitors; Free Radical Scavengers; HSP70 Heat-Shock Proteins; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Ketocholesterols; Lipoproteins, LDL; Oxygen; Proteins; Stress, Physiological

2009
Perilipin 2 (PLIN2)-deficiency does not increase cholesterol-induced toxicity in macrophages.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Analysis of Variance; Animals; Apoptosis; Atherosclerosis; Azo Compounds; Blotting, Western; Cell Culture Techniques; Cholesterol, LDL; DNA Primers; Endoplasmic Reticulum Stress; Foam Cells; In Situ Nick-End Labeling; Interleukin-6; Ketocholesterols; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Perilipin-2; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2012
Roles of 7-ketocholesterol on the homeostasis of intracellular cholesterol level.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:2

    Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Cholesterol; Disease Models, Animal; Homeostasis; Humans; Imidazoles; Ketocholesterols; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Plaque, Atherosclerotic; Protein Kinase Inhibitors; Pyridines; Squalene Monooxygenase; Time Factors; Up-Regulation

2012
Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca(2+) increase and oxidative stress.
    The British journal of nutrition, 2013, Jul-28, Volume: 110, Issue:2

    Topics: Apoptosis; Atherosclerosis; Betaxanthins; Calcium; Cell Line; Cytosol; Dietary Supplements; Fruit; Humans; Ketocholesterols; Macrophages; Mitochondria; Monocytes; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Opuntia; Oxidative Stress; Phytotherapy; Plant Extracts; Plaque, Atherosclerotic; Pyridines; Reactive Oxygen Species; Sulfhydryl Compounds

2013
11β-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoE⁻/⁻ mice.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Analysis of Variance; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Bone Marrow Transplantation; Cholesterol; Diet, Atherogenic; Foam Cells; Glucocorticoids; Ketocholesterols; Lipids; Male; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptors

2013
Lipids deposited in human atheromatous lesions induce apoptosis of human vascular smooth muscle cells.
    Journal of atherosclerosis and thrombosis, 2006, Volume: 13, Issue:5

    Topics: Aorta; Apoptosis; Atherosclerosis; Cells, Cultured; Coronary Vessels; Humans; In Situ Nick-End Labeling; Ketocholesterols; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Tunica Intima

2006
Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice.
    Free radical biology & medicine, 2008, Feb-01, Volume: 44, Issue:3

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Endothelium, Vascular; Glutathione Peroxidase; Humans; Ketocholesterols; Lipid Peroxidation; Lipids; Lysophosphatidylcholines; Mice; Mice, Transgenic; Monocytes; Phospholipid Hydroperoxide Glutathione Peroxidase

2008
Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1.
    The Journal of biological chemistry, 2008, Apr-11, Volume: 283, Issue:15

    Topics: Animals; Aorta; Atherosclerosis; Diabetes Mellitus, Experimental; Endothelial Cells; Janus Kinase 2; Ketocholesterols; Male; Profilins; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Steroid; STAT3 Transcription Factor; Up-Regulation

2008
Differential effects of PARP inhibition on vascular cell survival and ACAT-1 expression favouring atherosclerotic plaque stability.
    Cardiovascular research, 2008, Jun-01, Volume: 78, Issue:3

    Topics: Acetyl-CoA C-Acetyltransferase; Actins; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Caspase 3; Cells, Cultured; Disease Models, Animal; DNA Damage; Endothelial Cells; Enzyme Inhibitors; Foam Cells; Hydrogen Peroxide; Isoquinolines; Ketocholesterols; MAP Kinase Kinase 4; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Necrosis; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thiophenes; Time Factors; Tumor Necrosis Factor-alpha

2008