7-ketocholesterol has been researched along with Age-Related Macular Degeneration in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bobadilla, M; Larráyoz, IM; Ochoa, R; Pariente, A; Peláez, R; Pérez-Sala, Á; Villanueva-Martínez, Á | 1 |
| Catchpole, T; Csaky, KG; Dey, S; Takacs, A | 1 |
| Cung, T; Hartnett, ME; Nguyen, J; Ramshekar, A; Stoddard, GJ; Wallace-Carrete, C; Wang, H; Zaugg, C | 1 |
| Larráyoz, IM; Pariente, A; Peláez, R; Pérez-Sala, Á | 1 |
| Gu, Q; Qiu, Q; Wu, X; Xie, L; Yang, C; Yin, L | 1 |
| Hartnett, ME; Kunz, E; Ramshekar, A; Wang, H | 1 |
| Dasari, B; Ghribi, O; Meiers, C; Prasanthi, JR; Singh, BB | 1 |
| Fariss, RN; Indaram, M; Ma, W; Rodriguez, IR; Wong, WT; Zhao, L | 1 |
| Javitt, JC; Javitt, NB | 1 |
| Larrayoz, IM; Rodríguez, IR | 1 |
3 review(s) available for 7-ketocholesterol and Age-Related Macular Degeneration
| Article | Year |
|---|---|
Inflammatory and cell death mechanisms induced by 7-ketocholesterol in the retina. Implications for age-related macular degeneration.
Topics: Animals; Cell Death; Enzyme Inhibitors; Humans; Inflammation; Ketocholesterols; Macular Degeneration; Oxidation-Reduction; Retina; Retinal Pigment Epithelium; Retinitis | 2019 |
The retinal oxysterol pathway: a unifying hypothesis for the cause of age-related macular degeneration.
Topics: Animals; Humans; Ketocholesterols; Macrophages; Macular Degeneration; Metalloproteases; Retina; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A | 2009 |
Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration.
Topics: Animals; Cell Death; Cholesterol; Humans; Inflammation; Ketocholesterols; Macular Degeneration; Oxidation-Reduction; Retina | 2010 |
7 other study(ies) available for 7-ketocholesterol and Age-Related Macular Degeneration
| Article | Year |
|---|---|
Identification of 7-Ketocholesterol-Modulated Pathways and Sterculic Acid Protective Effect in Retinal Pigmented Epithelium Cells by Using Genome-Wide Transcriptomic Analysis.
Topics: Epithelium; Humans; Ketocholesterols; Macular Degeneration; Retinal Pigment Epithelium; Transcriptome | 2023 |
Investigating the effects of 7-ketocholesterol on retinal pigment epithelium bioenergetics.
Topics: Adenosine Triphosphate; Energy Metabolism; Humans; Macular Degeneration; Retina; Retinal Pigment Epithelium | 2023 |
7-Ketocholesterol Promotes Retinal Pigment Epithelium Senescence and Fibrosis of Choroidal Neovascularization via IQGAP1 Phosphorylation-Dependent Signaling.
Topics: Animals; Cellular Senescence; Choroidal Neovascularization; Fibrosis; Humans; Macular Degeneration; Mammals; Mice; Phosphorylation; ras GTPase-Activating Proteins; Retinal Pigment Epithelium; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2023 |
7-Ketocholesterol disturbs RPE cells phagocytosis of the outer segment of photoreceptor and induces inflammation through ERK signaling pathway.
Topics: Animals; Blotting, Western; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Inflammation; Ketocholesterols; Macular Degeneration; Male; Microscopy, Electron, Transmission; Phagocytosis; Rats; Rats, Sprague-Dawley; Retinal Photoreceptor Cell Outer Segment; Retinal Pigment Epithelium; RNA; Signal Transduction | 2019 |
7-ketocholesterol induces endothelial-mesenchymal transition and promotes fibrosis: implications in neovascular age-related macular degeneration and treatment.
Topics: Animals; Cell Movement; Choroid; Choroidal Neovascularization; Endothelial Cells; Fibrosis; Ketocholesterols; Macular Degeneration; Mice | 2021 |
Differential effects of the estrogen receptor agonist estradiol on toxicity induced by enzymatically-derived or autoxidation-derived oxysterols in human ARPE-19 cells.
Topics: Cell Line; Chemokine CCL2; Drug Interactions; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Hydroxycholesterols; Interleukin-6; Interleukin-8; Ketocholesterols; Liver X Receptors; Macular Degeneration; Orphan Nuclear Receptors; Oxidation-Reduction; Platelet-Derived Growth Factor; Retinal Pigment Epithelium; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2013 |
7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration.
Topics: Animals; Cell Proliferation; Cell Survival; Chemotactic Factors; CX3C Chemokine Receptor 1; Disease Models, Animal; Gene Expression Regulation; Ketocholesterols; Macular Degeneration; Mice; Mice, Transgenic; Microglia; Neovascularization, Pathologic; Nerve Growth Factors; Receptors, Chemokine; Retina | 2015 |