7-hydroxystaurosporine has been researched along with Leukemia, Myeloid, Acute in 7 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 6 (85.71) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cavelier, C; Demur, C; Didier, C; Ducommun, B; Manenti, S; Mansat-De Mas, V; Prade, N; Recher, C | 1 |
Azuma, A; Chubb, S; Guo, Y; Hittelman, W; Huang, P; Jiang, Y; Li, Y; Liu, X; Matsuda, A; Plunkett, W | 1 |
Andreeff, M; Cortes, J; Du, M; Estrov, Z; Gandhi, V; Plunkett, W; Sampath, D; Shi, Z | 1 |
Guo, L; Liu, X; Nishikawa, K; Plunkett, W | 1 |
Cavelier, C; Demur, C; Didier, C; Ducommun, B; Galcera, MO; Laurent, G; Manenti, S; Quaranta, M | 1 |
Pommier, Y; Shao, RG; Shimizu, T | 1 |
Azuma, A; Huang, P; Li, YX; Plunkett, W; Sampath, D; Shi, Z | 1 |
1 trial(s) available for 7-hydroxystaurosporine and Leukemia, Myeloid, Acute
Article | Year |
---|---|
Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blast Crisis; Cell Cycle; Checkpoint Kinase 1; Cyclin-Dependent Kinase 2; Cytarabine; DNA Damage; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid, Acute; Middle Aged; Oncogene Protein v-akt; Pharmacokinetics; Phosphorylation; Pilot Projects; Protein Kinases; Salvage Therapy; Staurosporine; Tumor Cells, Cultured | 2006 |
6 other study(ies) available for 7-hydroxystaurosporine and Leukemia, Myeloid, Acute
Article | Year |
---|---|
Constitutive activation of the DNA damage signaling pathway in acute myeloid leukemia with complex karyotype: potential importance for checkpoint targeting therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Checkpoint Kinase 1; Child; Chromosome Aberrations; DNA Damage; Flow Cytometry; Fluorescent Antibody Technique; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Middle Aged; Protein Kinases; RNA Interference; Signal Transduction; Staurosporine | 2009 |
Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Checkpoint Kinase 1; Chromosome Aberrations; Cytarabine; DNA Damage; Drug Interactions; G2 Phase; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Mitosis; Protein Kinases; Signal Transduction; Staurosporine | 2005 |
Inhibition of topoisomerase IIalpha and G2 cell cycle arrest by NK314, a novel benzo[c]phenanthridine currently in clinical trials.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Chromosome Aberrations; Clinical Trials as Topic; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; G2 Phase; Histones; Humans; Leukemia, Myeloid, Acute; Phenanthrenes; Phenanthridines; Phosphorylation; Staurosporine; Topoisomerase II Inhibitors | 2007 |
G2/M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress.
Topics: Antigens, CD; Antigens, CD34; Antineoplastic Agents; cdc25 Phosphatases; Cell Division; Cell Line, Tumor; Colony-Forming Units Assay; G2 Phase; Humans; Leukemia, Myeloid, Acute; Mitosis; Nocodazole; Staurosporine; U937 Cells | 2008 |
7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53.
Topics: Adenocarcinoma; Alkaloids; Apoptosis; Caspase 3; Caspases; CDC2 Protein Kinase; Colonic Neoplasms; Cyclin B; Cyclin B1; Cyclins; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; HT29 Cells; Humans; Lamin Type B; Lamins; Leukemia, Myeloid, Acute; Nuclear Proteins; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Synthesis Inhibitors; Serine Proteinase Inhibitors; Staurosporine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1997 |
S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine.
Topics: Alkaloids; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Leukemia, Myeloid, Acute; S Phase; Staurosporine; Tumor Cells, Cultured | 2001 |