7-hydroxystaurosporine has been researched along with Experimental Neoplasms in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aslanian, AS; Lees, JA; Reinhardt, HC; Yaffe, MB | 1 |
| Akinaga, S; Gomi, K; Nomura, K; Okabe, M | 1 |
| Saijo, N | 1 |
| Akinaga, S; Akiyama, T; Fuse, E; Kobayashi, H; Kobayashi, S; Kurata, N; Kuwabara, T; Tanii, H; Yamaguchi, K | 1 |
| Abe, S; Akinaga, S; Akiyama, T; Furukawa, T; Kitajima, M; Kubota, T; Kumai, K; Otani, Y; Watanabe, M | 1 |
| Akinaga, S; Gomi, K; Morimoto, M; Okabe, M; Tamaoki, T | 1 |
1 review(s) available for 7-hydroxystaurosporine and Experimental Neoplasms
| Article | Year |
|---|---|
New chemotherapeutic agents for the treatment of non-small cell lung cancer: the Japanese experience.
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbazoles; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Docetaxel; Glucosides; Humans; Irinotecan; Japan; Lung Neoplasms; Mitomycin; Mitomycins; Neoplasms, Experimental; Paclitaxel; Purine Nucleosides; Staurosporine; Taxoids; Treatment Outcome; Vinblastine; Vinorelbine | 1998 |
5 other study(ies) available for 7-hydroxystaurosporine and Experimental Neoplasms
| Article | Year |
|---|---|
p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Bone Neoplasms; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Survival; Cells, Cultured; Cisplatin; DNA Damage; DNA Repair; DNA-Binding Proteins; Doxorubicin; G2 Phase; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Mice, Nude; Mitosis; Neoplasms, Experimental; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; S Phase; Signal Transduction; Staurosporine; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ultraviolet Rays | 2007 |
Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C.
Topics: Alkaloids; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Division; Drug Synergism; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Nude; Mitomycin; Neoplasm Transplantation; Neoplasms, Experimental; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1993 |
Pharmacokinetics and pharmacodynamics of a novel protein kinase inhibitor, UCN-01.
Topics: Alkaloids; Animals; Antineoplastic Agents; Dogs; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Pancreatic Neoplasms; Rats; Rats, Sprague-Dawley; Staurosporine; Tissue Distribution; Transplantation, Heterologous | 1999 |
UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery.
Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Division; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA, Neoplasm; Drug Resistance, Neoplasm; G1 Phase; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Retinoblastoma Protein; Staurosporine; Transplantation, Heterologous | 2001 |
Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Division; Down-Regulation; ErbB Receptors; Humans; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Oncogenes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |