Compounds > 7-hydroxystaurosporine
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7-hydroxystaurosporine and Colorectal Neoplasms

7-hydroxystaurosporine has been researched along with Colorectal Neoplasms in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jain, A; Jain, R; Jain, S; Kohli, DV1
Biffoni, M; Buccarelli, M; Cappellari, M; De Luca, G; Fanciulli, M; Goeman, F; Melucci, E; Pilozzi, E; Ricci-Vitiani, L; Signore, M1
Kwak, S; Theurkauf, WE; Varmark, H1
Hicks, DJ; Paraskeva, C; Playle, LC; Qualtrough, D1
Desai, AB; Jacobberger, JW; Kinsella, TJ; Loh, T; Sramkoski, RM; Yan, T1

Other Studies

5 other study(ies) available for 7-hydroxystaurosporine and Colorectal Neoplasms

ArticleYear
Coated chitosan nanoparticles encapsulating caspase 3 activator for effective treatment of colorectral cancer.
    Drug delivery and translational research, 2015, Volume: 5, Issue:6

    Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Caspase 3; Chitosan; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Enzyme Activation; Formazans; Humans; Nanoparticles; Particle Size; Polymethacrylic Acids; Rabbits; Staurosporine; Tetrazolium Salts

2015
UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; DNA Damage; Drug Synergism; HCT116 Cells; Humans; Irinotecan; Mice; Neoplastic Stem Cells; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Xenograft Model Antitumor Assays

2016
A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells.
    Cell cycle (Georgetown, Tex.), 2010, Jan-15, Volume: 9, Issue:2

    Topics: Animals; Caffeine; Checkpoint Kinase 1; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Breaks, Double-Stranded; DNA Damage; Drosophila; G2 Phase; Gene Knockout Techniques; HCT116 Cells; Humans; Mitosis; Protein Kinases; Protein Serine-Threonine Kinases; Signal Transduction; Staurosporine

2010
Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines.
    British journal of cancer, 2002, Jul-29, Volume: 87, Issue:3

    Topics: Alkaloids; Antineoplastic Agents; Colorectal Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; G2 Phase; Humans; Radiation-Sensitizing Agents; Staurosporine; Tumor Cells, Cultured; Tumor Stem Cell Assay

2002
CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:9

    Topics: Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Base Pair Mismatch; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Repair; DNA-Binding Proteins; Humans; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Staurosporine; Thioguanine; Tumor Suppressor Proteins

2004