7-hydroxystaurosporine has been researched along with Cancer of Pancreas in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, P; Gronda, M; Hedley, DW; Jacobberger, JW; Pham, NA; Schimmer, AD | 1 |
| Akinaga, S; Akiyama, T; Fuse, E; Kobayashi, H; Kobayashi, S; Kurata, N; Kuwabara, T; Tanii, H; Yamaguchi, K | 1 |
| Abe, S; Kitajima, M; Kubota, T; Kumai, K; Otani, Y; Watanabe, A | 1 |
| Abe, S; Furukawa, T; Kitajima, M; Kubota, T; Kumai, K; Otani, Y; Watanabe, M | 1 |
| Abe, S; Akinaga, S; Akiyama, T; Furukawa, T; Kitajima, M; Kubota, T; Kumai, K; Otani, Y; Watanabe, M | 1 |
5 other study(ies) available for 7-hydroxystaurosporine and Cancer of Pancreas
| Article | Year |
|---|---|
The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice.
Topics: Animals; Anticarcinogenic Agents; Antigens; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspases; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Glutathione; Humans; Isothiocyanates; Male; Membrane Potentials; Mice; Mice, SCID; Microscopy, Fluorescence; Mitochondria; Mitosis; Neoplasm Transplantation; Neoplasms; Oxidative Stress; Pancreatic Neoplasms; Reactive Oxygen Species; Staurosporine; Sulfoxides; Thiocyanates; Time Factors; Tyrosine | 2004 |
Pharmacokinetics and pharmacodynamics of a novel protein kinase inhibitor, UCN-01.
Topics: Alkaloids; Animals; Antineoplastic Agents; Dogs; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Pancreatic Neoplasms; Rats; Rats, Sprague-Dawley; Staurosporine; Tissue Distribution; Transplantation, Heterologous | 1999 |
[Antineoplastic effect of novel agents, UCN-01 on human tumor cells transplanted in nude mice].
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Cycle; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Staurosporine; Stomach Neoplasms | 1999 |
UCN-01 (7-hydroxystaurosporine) enhances 5-fluorouracil cytotoxicity through down-regulation of thymidylate synthetase messenger RNA.
Topics: Alkaloids; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Staurosporine; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery.
Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Division; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA, Neoplasm; Drug Resistance, Neoplasm; G1 Phase; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Retinoblastoma Protein; Staurosporine; Transplantation, Heterologous | 2001 |