7-hydroxystaurosporine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunleavy, K; Figg, WD; Grant, ND; Jaffe, ES; Janik, JE; Marti, GE; Steinberg, SM; Stetler-Stevenson, M; Tohnya, T; White, T; Wilson, WH | 1 |
| Cheson, BD | 1 |
| Keating, MJ; Plunkett, W; Yamauchi, T | 1 |
| Byrd, JC; Grever, MR; Rai, KR; Sausville, EA | 1 |
| Byrd, JC; Flinn, IW; Grever, MR; Lehman, T; Lucas, D; Sausville, E; Shinn, C; Willis, CR | 1 |
2 review(s) available for 7-hydroxystaurosporine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Hematologic malignancies: new developments and future treatments.
Topics: Adenine Nucleotides; Alemtuzumab; Alkaloids; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Cell Cycle; Cell Survival; Clofarabine; Cytosine; Dioxolanes; Flavonoids; Hematologic Neoplasms; Humans; Immunoconjugates; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; NF-kappa B; Nitrogen Mustard Compounds; Oligonucleotides, Antisense; Peptide Hydrolases; Piperidines; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Remission Induction; Rituximab; Staurosporine; Thionucleotides | 2002 |
Old and new therapies in chronic lymphocytic leukemia: now is the time for a reassessment of therapeutic goals.
Topics: Alkaloids; Antineoplastic Agents, Alkylating; Bryostatins; Flavonoids; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Piperidines; Staurosporine; Topoisomerase I Inhibitors | 1998 |
1 trial(s) available for 7-hydroxystaurosporine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Phase I trial of 7-hydroxystaurosporine and fludararbine phosphate: in vivo evidence of 7-hydroxystaurosporine induced apoptosis in chronic lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytosis; Male; Middle Aged; Staurosporine; Treatment Outcome; Vidarabine Phosphate | 2011 |
2 other study(ies) available for 7-hydroxystaurosporine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
UCN-01 (7-hydroxystaurosporine) inhibits DNA repair and increases cytotoxicity in normal lymphocytes and chronic lymphocytic leukemia lymphocytes.
Topics: Alkaloids; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cells, Cultured; Cyclophosphamide; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Combinations; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Staurosporine; Ultraviolet Rays | 2002 |
UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism.
Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Cells, Cultured; Chlorambucil; Drug Resistance, Multiple; Genes, bcl-2; Humans; Interleukin-4; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Mice, Inbred C57BL; Mice, Knockout; Prednisone; Proto-Oncogene Proteins c-bcl-2; Spleen; Staurosporine; Thymus Gland; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vidarabine | 2001 |