Compounds > 7-hydroxystaurosporine
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7-hydroxystaurosporine and Astrocytoma, Grade IV

7-hydroxystaurosporine has been researched along with Astrocytoma, Grade IV in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biffoni, M; De Majo, M; De Maria, R; di Martino, S; Giannetti, S; Larocca, LM; Morgante, L; Pallini, R; Pelacchi, F; Petricoin, EF; Ricci-Vitiani, L; Runci, D; Signore, M; Stancato, L1
Dai, Y; Dent, P; Grant, S; Tang, Y1
Cao, JP; Fan, SJ; Luo, JL; Meng, QH; Tong, J; Zhou, LX1
Berger, MS; Hirose, Y; Pieper, RO1

Other Studies

4 other study(ies) available for 7-hydroxystaurosporine and Astrocytoma, Grade IV

ArticleYear
Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo.
    Cell death & disease, 2014, May-08, Volume: 5

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; Neoplastic Stem Cells; Protein Array Analysis; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proteomics; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Signal Transduction; Small Molecule Libraries; Staurosporine; Temozolomide; Time Factors; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2014
Enhancing CHK1 inhibitor lethality in glioblastoma.
    Cancer biology & therapy, 2012, Volume: 13, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Benzamides; Benzimidazoles; Checkpoint Kinase 1; Glioblastoma; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase 4; Medulloblastoma; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Protein Kinases; Radiation-Sensitizing Agents; src-Family Kinases; Staurosporine; Tumor Cells, Cultured

2012
Effect of 7-hydroxystaurosporine on glioblastoma cell invasion and migration.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:4

    Topics: BRCA1 Protein; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioblastoma; Humans; Protein Kinase C; RNA, Messenger; Staurosporine

2005
Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Cancer research, 2001, Aug-01, Volume: 61, Issue:15

    Topics: Alkaloids; Antineoplastic Agents, Alkylating; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Checkpoint Kinase 1; Dacarbazine; Drug Synergism; Enzyme Inhibitors; G2 Phase; Glioblastoma; Humans; Mitosis; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001