Compounds > 7-hydroxy-4-trifluoromethylcoumarin

7-hydroxy-4-trifluoromethylcoumarin and Prostatic-Neoplasms

7-hydroxy-4-trifluoromethylcoumarin has been researched along with Prostatic-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 7-hydroxy-4-trifluoromethylcoumarin and Prostatic-Neoplasms

Article	Year
Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 The synthesis and SAR studies of 3- and 4-substituted 7-hydroxycoumarins as novel 17beta-HSD3 inhibitors are discussed. The most potent compounds from this series exhibited low nanomolar inhibitory activity with acceptable selectivity versus other 17beta-HSD isoenzymes and nuclear receptors. Topics: 17-Hydroxysteroid Dehydrogenases; Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Humans; Male; Molecular Conformation; Prostatic Neoplasms; Pyridines; Umbelliferones	2010

Article

Year

Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer.

Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

The synthesis and SAR studies of 3- and 4-substituted 7-hydroxycoumarins as novel 17beta-HSD3 inhibitors are discussed. The most potent compounds from this series exhibited low nanomolar inhibitory activity with acceptable selectivity versus other 17beta-HSD isoenzymes and nuclear receptors.

Topics: 17-Hydroxysteroid Dehydrogenases; Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Humans; Male; Molecular Conformation; Prostatic Neoplasms; Pyridines; Umbelliferones

2010