7-hydroxy-2-n,n-dipropylaminotetralin has been researched along with Alzheimer Disease in 3 studies
7-hydroxy-2-N,N-dipropylaminotetralin: RN given refers to cpd without isomeric designation
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Consecutive cases from the Alzheimer's Disease Research Center brain bank, neuroleptic free for at least 1 month prior to death, with neuropathologic diagnoses of AD with LB (AD + LB, n = 14), AD without LB (AD, n = 13), or normal brains (n = 8)." | 1.31 | Alterations of striatal dopamine receptor binding in Alzheimer disease are associated with Lewy body pathology and antemortem psychosis. ( DeKosky, ST; Hamilton, RL; Healy, MT; Henteleff, R; Lewis, DA; Pollock, BG; Sweet, RA; Wisniewski, SR, 2001) |
| "Distinguishing Alzheimer's disease from DLB is clinically relevant in terms of prognosis and appropriate treatment." | 1.30 | Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution. ( Ballard, C; Burn, D; Court, JA; Jaros, E; Johnson, M; Lloyd, S; Marshall, EF; McKeith, IG; Perry, EK; Perry, RH; Piggott, MA; Thomas, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piggott, MA | 1 |
| Marshall, EF | 1 |
| Thomas, N | 1 |
| Lloyd, S | 1 |
| Court, JA | 1 |
| Jaros, E | 1 |
| Burn, D | 1 |
| Johnson, M | 1 |
| Perry, RH | 1 |
| McKeith, IG | 1 |
| Ballard, C | 1 |
| Perry, EK | 1 |
| Barbanti, P | 1 |
| Fabbrini, G | 1 |
| Ricci, A | 1 |
| Bruno, G | 1 |
| Cerbo, R | 1 |
| Bronzetti, E | 1 |
| Amenta, F | 1 |
| Luigi Lenzi, G | 1 |
| Sweet, RA | 1 |
| Hamilton, RL | 1 |
| Healy, MT | 1 |
| Wisniewski, SR | 1 |
| Henteleff, R | 1 |
| Pollock, BG | 1 |
| Lewis, DA | 1 |
| DeKosky, ST | 1 |
3 other studies available for 7-hydroxy-2-n,n-dipropylaminotetralin and Alzheimer Disease
| Article | Year |
|---|---|
Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Corpus Striatum; Dementia; Dopamine; Fe | 1999 |
Reduced density of dopamine D2-like receptors on peripheral blood lymphocytes in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Benzazepines; Case-Control Studies; Dopamine Agonists; D | 2000 |
Alterations of striatal dopamine receptor binding in Alzheimer disease are associated with Lewy body pathology and antemortem psychosis.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Benzazepines; Case-Control Studies; Corpus Striatum; Dop | 2001 |