7-deazaguanine and Flavivirus-Infections

7-deazaguanine has been researched along with Flavivirus-Infections* in 1 studies

Other Studies

1 other study(ies) available for 7-deazaguanine and Flavivirus-Infections

Article	Year
Synthesis of 5-aza-7-deazaguanine nucleoside derivatives as potential anti-flavivirus agents. Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7 Coupling suitable sugars (D- or L-ribofuranose, 2' or 3-deoxysugar, branched sugars) with 2-aminoimidazo[1,2-a]-s-triazin-4-one was carried out using the different reaction conditions: 1) condensation in the presence of sodium hydride; or 2) condensation using Vorbrüggen's methods. The 5-aza- 7-deazaguanine nucleoside analogues obtained were evaluated in cell culture experiments for the inhibition of the replication of a number of RNA viruses, including BVDV, YFV, and WNV. Topics: Antiviral Agents; Chemistry, Pharmaceutical; Drug Design; Flavivirus; Flavivirus Infections; Guanine; Guanosine; Humans; Models, Chemical; Nucleosides; Pyrimidine Nucleosides; Ribonucleosides	2005

Article

Year

Synthesis of 5-aza-7-deazaguanine nucleoside derivatives as potential anti-flavivirus agents.

Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

Coupling suitable sugars (D- or L-ribofuranose, 2' or 3-deoxysugar, branched sugars) with 2-aminoimidazo[1,2-a]-s-triazin-4-one was carried out using the different reaction conditions: 1) condensation in the presence of sodium hydride; or 2) condensation using Vorbrüggen's methods. The 5-aza- 7-deazaguanine nucleoside analogues obtained were evaluated in cell culture experiments for the inhibition of the replication of a number of RNA viruses, including BVDV, YFV, and WNV.

Topics: Antiviral Agents; Chemistry, Pharmaceutical; Drug Design; Flavivirus; Flavivirus Infections; Guanine; Guanosine; Humans; Models, Chemical; Nucleosides; Pyrimidine Nucleosides; Ribonucleosides

2005