7-chlorokynurenic acid has been researched along with Convulsions, Grand Mal in 1 studies
7-chlorokynurenic acid: selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex; structure given in first source
7-chlorokynurenic acid : A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Battaglia, G | 1 |
| La Russa, M | 1 |
| Bruno, V | 1 |
| Arenare, L | 1 |
| Ippolito, R | 1 |
| Copani, A | 1 |
| Bonina, F | 1 |
| Nicoletti, F | 1 |
1 other study available for 7-chlorokynurenic acid and Convulsions, Grand Mal
| Article | Year |
|---|---|
Systemically administered D-glucose conjugates of 7-chlorokynurenic acid are centrally available and exert anticonvulsant activity in rodents.
Topics: Animals; Anticonvulsants; Astrocytes; Biotransformation; Blood-Brain Barrier; Cells, Cultured; Cereb | 2000 |