7-chlorokynurenic acid has been researched along with Cognition Disorders in 1 studies
7-chlorokynurenic acid: selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex; structure given in first source
7-chlorokynurenic acid : A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramakers, GM | 1 |
| Urban, IJ | 1 |
| De Graan, PN | 1 |
| Di Luca, M | 1 |
| Cattabeni, F | 1 |
| Gispen, WH | 1 |
1 other study available for 7-chlorokynurenic acid and Cognition Disorders
| Article | Year |
|---|---|
The impaired long-term potentiation in the CA1 field of the hippocampus of cognitive deficient microencephalic rats is restored by D-serine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cognition Disorders; Electric Stimulation; Electrophysi | 1993 |