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7-chlorokynurenic acid and Astrocytosis

7-chlorokynurenic acid has been researched along with Astrocytosis in 1 studies

7-chlorokynurenic acid: selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex; structure given in first source
7-chlorokynurenic acid : A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.

Research Excerpts

ExcerptRelevanceReference
"Neuronal loss and gliosis in these animals were examined immunohistochemically."1.33Kynurenate and 7-chlorokynurenate formation in chronically epileptic rats. ( Bertram, EH; Goodman, JH; Rassoulpour, A; Scharfman, HE; Schwarcz, R; Wu, HQ, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, HQ1
Rassoulpour, A1
Goodman, JH1
Scharfman, HE1
Bertram, EH1
Schwarcz, R1

Other Studies

1 other study available for 7-chlorokynurenic acid and Astrocytosis

ArticleYear
Kynurenate and 7-chlorokynurenate formation in chronically epileptic rats.
    Epilepsia, 2005, Volume: 46, Issue:7

    Topics: Animals; Astrocytes; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Epilepsy, Temporal Lobe; E

2005