7-chlorokynurenic acid has been researched along with Anterior Circulation Transient Ischemic Attack in 2 studies
7-chlorokynurenic acid: selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex; structure given in first source
7-chlorokynurenic acid : A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wood, ER | 2 |
| Bussey, TJ | 2 |
| Phillips, AG | 2 |
2 other studies available for 7-chlorokynurenic acid and Anterior Circulation Transient Ischemic Attack
| Article | Year |
|---|---|
A glycine antagonist 7-chlorokynurenic acid attenuates ischemia-induced learning deficits.
Topics: Analysis of Variance; Animals; Cerebral Ventricles; Discrimination, Psychological; Glycine; Hippocam | 1993 |
A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo.
Topics: Animals; Glycine; Hippocampus; Injections, Intraventricular; Ischemic Attack, Transient; Kynurenic A | 1992 |