7-chlorokynurenic acid has been researched along with Aging in 3 studies
7-chlorokynurenic acid: selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex; structure given in first source
7-chlorokynurenic acid : A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhong, J | 1 |
| Gribkoff, VK | 1 |
| Molinoff, PB | 1 |
| Clayton, DA | 1 |
| Mesches, MH | 1 |
| Alvarez, E | 1 |
| Bickford, PC | 1 |
| Browning, MD | 1 |
| Aamodt, SM | 1 |
| Kozlowski, MR | 1 |
| Nordeen, EJ | 1 |
| Nordeen, KW | 1 |
3 other studies available for 7-chlorokynurenic acid and Aging
| Article | Year |
|---|---|
Use of subunit-specific antisense oligodeoxynucleotides to define developmental changes in the properties of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Base Sequence; Cerebral Cortex; Excit | 1996 |
A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat.
Topics: Action Potentials; Aging; Animals; Behavior, Animal; Blotting, Western; Calcium Channel Blockers; Ca | 2002 |
Distribution and developmental change in [3H]MK-801 binding within zebra finch song nuclei.
Topics: Aging; Animals; Auditory Pathways; Autoradiography; Binding, Competitive; Birds; Dizocilpine Maleate | 1992 |