Page last updated: 2024-08-23

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Pregnancy

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with Pregnancy in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19906 (19.35)18.7374
1990's7 (22.58)18.2507
2000's3 (9.68)29.6817
2010's2 (6.45)24.3611
2020's13 (41.94)2.80

Authors

AuthorsStudies
Chen, W; Dai, M; Huang, W; Liang, T; Mi, C; Tian, P; Xie, J; Xu, Z; Zhang, H; Zhang, S1
Han, M; Ji, J; Liu, S; Wei, J; Wu, Y; Zhang, J1
Dai, M; Deng, Y; Huang, W; Huang, X; Ma, C; Xu, X; Yang, J; Yang, Y; Zhang, H1
He, YL; Meng, YQ; Nie, JS; Ren, ZP; Tang, DL; Wang, HM; Wang, HW; Wang, LJ1
Chen, X; Ding, Y; Gao, R; Geng, Y; He, J; Li, F; Liu, T; Liu, X; Mu, X; Wang, Y; Xu, H; Yang, J; Zhou, M1
Ao, L; Chen, W; Cheng, L; Liang, T; Liu, Q; Wang, R; Xie, J; Zhang, H; Zhao, J1
Chen, W; Huang, W; Wang, M; Wang, R; Xu, X; Yang, J; Yang, Y; Zhang, H; Zhang, Y; Zhao, J1
Chen, W; Mi, C; Shen, Y; Wan, S; Wang, X; Xu, X; Xu, Z; Yang, Y; Zhang, H; Zhang, Y; Zhao, J; Zheng, Z1
Huang, X; Ma, C; Wang, R; Zhang, H1
Dai, M; Huang, W; Liang, T; Mi, C; Tian, P; Xie, J; Xu, Z; Zhang, H; Zhang, S; Zhao, J1
Chen, W; Dai, M; Guo, J; Huang, W; Liang, T; Mi, C; Tian, P; Xie, J; Xu, Z; Zhang, H1
Chen, W; Huang, W; Liang, T; Mi, C; Tian, P; Wang, R; Xie, J; Xu, Z; Zhang, H; Zhao, J1
Chen, W; Dai, M; Huang, W; Liang, T; Mi, C; Qiu, T; Tian, P; Xie, J; Zhang, H; Zhang, S; Zhao, J1
Guo, L; Jiang, X; Li, BY; Sun, X; Tian, HY; Yao, SJ; Zhang, RJ; Zhang, SS1
Ciardelli, R; Decordier, I; Haumont, D; Kirsch-Volders, M; Plas, G; Vande Loock, K1
Balascak, I; Libalova, H; Milcova, A; Novakova, Z; Rossner, P; Sram, RJ; Topinka, J1
King, LC; Kirlin, WG; Kohan, MJ; Rodriguez, JW1
Larrañnaga, C; Patiñno-García, A; Sierrasesumaga, L; Zalacain, M1
Callaham, MF; Huberman, E; Jones, CA1
Etkin, S; Lavi, S1
Amin, S; Dai, W; Desai, D; Harvey, RG; Hecht, SS1
Fujita, I; Kikkawa, Y; Rasmussen, RE; Sindhu, RK; Yamamoto, R1
Lee, X; Lewtas, J; Mumford, JL; Santella, RM; Young, TL1
Kikkawa, Y; Rasmussen, RE; Sindhu, RK1
Israels, ED; Israels, LG1
Bielecki, R; Puy, LA; Reed, TE; Zenzes, MT1
Bowman, ED; Harris, CC; Manchester, DK; Weston, A1
Gelboin, HV; Park, SS; Pasanen, M; Pelkonen, O; Raunio, H; Sivonen, P; Vähäkangas, K1
Choi, JS; Farmer, PB; Fennessey, PV; Harris, CC; Manchester, DK; Mann, DL; Quintana, E; Trivers, GE; Weston, A1
Disher, RM; Lu, LJ; Randerath, K; Reddy, MV1
Matsunami, R; Shugart, L1

Reviews

1 review(s) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Pregnancy

ArticleYear
Observations on vitamin K deficiency in the fetus and newborn: has nature made a mistake?
    Seminars in thrombosis and hemostasis, 1995, Volume: 21, Issue:4

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; Biotransformation; Carcinogens; Chick Embryo; Cocarcinogenesis; DNA Adducts; Female; Fetal Diseases; Fetus; Humans; Infant, Newborn; Liver; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms; Neoplasms, Experimental; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Smoking; Vitamin K; Vitamin K 1; Vitamin K Deficiency; Warfarin; Xenobiotics

1995

Other Studies

30 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Pregnancy

ArticleYear
Lnc-HZ05 regulates BPDE-inhibited human trophoblast cell proliferation and affects the occurrence of miscarriage by directly binding with miR-hz05.
    Cell biology and toxicology, 2022, Volume: 38, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Spontaneous; Benzo(a)pyrene; Cell Line; Cell Movement; Cell Proliferation; Female; Humans; MicroRNAs; Pregnancy; RNA, Long Noncoding; Trophoblasts

2022
Interactions between Benzo(a)pyrene exposure and genetic polymorphisms of AhR signaling pathway on missed abortion.
    International journal of environmental health research, 2023, Volume: 33, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Missed; Benzo(a)pyrene; DNA Adducts; Female; Humans; Polymorphism, Genetic; Pregnancy; Signal Transduction

2023
Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop.
    Ecotoxicology and environmental safety, 2022, Jun-01, Volume: 237

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Habitual; Apoptosis; Caspase 3; Feedback; Female; Humans; Pregnancy; RNA, Long Noncoding; Trophoblasts; Tumor Suppressor Protein p53

2022
[Association between cord blood BPDE-DNA and neurodevelopment of children aged 0 and 2 years: A birth cohort study].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2022, Jun-20, Volume: 40, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Birth Cohort; Child, Preschool; Cohort Studies; DNA Adducts; Female; Fetal Blood; Humans; Infant; Infant, Newborn; Polycyclic Aromatic Hydrocarbons; Pregnancy

2022
Exposure to Benzo(a)pyrene damages mitochondrial function via suppressing mitochondrial melatonin receptors in ovarian corpus luteum during early pregnancy.
    Chemico-biological interactions, 2022, Sep-25, Volume: 365

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenosine Triphosphate; Animals; Benzo(a)pyrene; Corpus Luteum; Environmental Pollutants; Female; Mammals; Mice; Mitochondria; Pregnancy; Progesterone; Rats; Receptors, Melatonin; Sirtuin 3

2022
Lnc-HZ03 promotes TRBP-mediated splicing of pre-miR-hz03 to generate miR-hz03 in human trophoblast cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2023, 02-17, Volume: 191, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Habitual; Female; Humans; MicroRNAs; Pregnancy; RNA, Long Noncoding; Transcription Factor TFIID; Trophoblasts

2023
BPDE exposure promotes trophoblast cell pyroptosis and induces miscarriage by up-regulating lnc-HZ14/ZBP1/NLRP3 axis.
    Journal of hazardous materials, 2023, 08-05, Volume: 455

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Spontaneous; Animals; Benzo(a)pyrene; Female; Humans; Methyltransferases; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Placenta; Pregnancy; Pyroptosis; RNA-Binding Proteins; Trophoblasts

2023
BaP/BPDE suppressed endothelial cell angiogenesis to induce miscarriage by promoting MARCHF1/GPX4-mediated ferroptosis.
    Environment international, 2023, Volume: 180

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Spontaneous; Animals; Benzo(a)pyrene; Endothelial Cells; Female; Ferroptosis; Humans; Mice; Placenta; Pregnancy; Proteins

2023
Toxicological Effects of BPDE on Dysfunctions of Female Trophoblast Cells.
    Advances in experimental medicine and biology, 2021, Volume: 1300

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Carcinogens; DNA Adducts; Female; Humans; Pregnancy; Trophoblasts

2021
Novel lnc-HZ03 and miR-hz03 promote BPDE-induced human trophoblastic cell apoptosis and induce miscarriage by upregulating p53/SAT1 pathway.
    Cell biology and toxicology, 2021, Volume: 37, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Spontaneous; Apoptosis; Female; Humans; MicroRNAs; Pregnancy; Tumor Suppressor Protein p53

2021
Lnc-HZ01 with m6A RNA methylation inhibits human trophoblast cell proliferation and induces miscarriage by up-regulating BPDE-activated lnc-HZ01/MXD1 positive feedback loop.
    The Science of the total environment, 2021, Jul-01, Volume: 776

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Spontaneous; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Proliferation; Feedback; Female; Humans; Methylation; Pregnancy; Repressor Proteins; RNA, Long Noncoding; Trophoblasts

2021
Lnc-HZ08 regulates BPDE-induced trophoblast cell dysfunctions by promoting PI3K ubiquitin degradation and is associated with miscarriage.
    Cell biology and toxicology, 2022, Volume: 38, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Spontaneous; Cell Movement; Estrogen Receptor alpha; Female; Humans; Ligases; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; RNA, Long Noncoding; Trophoblasts; Ubiquitin

2022
Novel lncRNA-HZ04 promotes BPDE-induced human trophoblast cell apoptosis and miscarriage by upregulating IP
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Abortion, Habitual; Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line; Down-Regulation; Female; Humans; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Inbred C57BL; MicroRNAs; Pregnancy; RNA, Long Noncoding; Sarcoglycans; Signal Transduction; Trophoblasts; Up-Regulation

2021
Detection of BPDE-DNA adducts in human umbilical cord blood by LC-MS/MS analysis.
    Journal of food and drug analysis, 2019, Volume: 27, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Chromatography, Liquid; DNA Adducts; Female; Fetal Blood; Humans; Molecular Conformation; Pregnancy; Tandem Mass Spectrometry

2019
Lower nucleotide excision repair capacity in newborns compared to their mothers: a pilot study.
    Reproductive toxicology (Elmsford, N.Y.), 2014, Volume: 43

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aphidicolin; Cells, Cultured; Comet Assay; DNA Adducts; DNA Polymerase II; DNA Polymerase III; DNA Repair; Enzyme Inhibitors; Female; Humans; Infant, Newborn; Leukocytes, Mononuclear; Mothers; Nuclear Family; Pilot Projects; Pregnancy

2014
Biomarkers of exposure to tobacco smoke and environmental pollutants in mothers and their transplacental transfer to the foetus. Part I: bulky DNA adducts.
    Mutation research, 2009, Oct-02, Volume: 669, Issue:1-2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Air Pollutants; Biomarkers; Cotinine; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Fetus; Humans; Infant, Newborn; Lymphocytes; Maternal Exposure; Maternal-Fetal Exchange; Placenta; Polycyclic Aromatic Hydrocarbons; Pregnancy; Smoking; Young Adult

2009
Detection of DNA adducts in developing CD4+ CD8+ thymocytes and splenocytes following in utero exposure to benzo[a]pyrene.
    Immunopharmacology and immunotoxicology, 2002, Volume: 24, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Carcinogens, Environmental; CD4 Antigens; CD8 Antigens; DNA Adducts; Female; Fetus; Humans; Immune Tolerance; Male; Mice; Mice, Inbred C3H; Neoplasms; Pregnancy; Smoking; Spleen; T-Lymphocytes

2002
Effects of benzopyrene-7,8-diol-9,10-epoxide (BPDE) in vitro and of maternal smoking in vivo on micronuclei frequencies in fetal cord blood.
    Pediatric research, 2006, Volume: 60, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Apoptosis; Female; Fetal Blood; Humans; Infant, Newborn; Lymphocytes; Maternal Exposure; Maternal-Fetal Exchange; Micronuclei, Chromosome-Defective; Micronucleus Tests; Pregnancy; Smoking

2006
Enhancement of chemical-carcinogen-induced cell transformation in hamster embryo cells by 1 alpha,25-dihydroxycholecalciferol, the biologically active metabolite of vitamin D3.
    Carcinogenesis, 1984, Volume: 5, Issue:9

    Topics: 24,25-Dihydroxyvitamin D 3; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Calcitriol; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cholecalciferol; Cricetinae; Dihydroxycholecalciferols; Embryo, Mammalian; Female; Mesocricetus; Methylnitronitrosoguanidine; Pregnancy

1984
Carcinogen-mediated induction of SV40 DNA synthesis in SV40 transformed Chinese hamster embryo cells.
    Carcinogenesis, 1981, Volume: 2, Issue:5

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Viral; Clone Cells; Cricetinae; Cricetulus; DNA, Viral; Embryo, Mammalian; Female; Pregnancy; Simian virus 40

1981
Tumorigenicity in newborn mice of fjord region and other sterically hindered diol epoxides of benzo[g]chrysene, dibenzo[a,l]pyrene (dibenzo[def,p]chrysene), 4H-cyclopenta[def]chrysene and fluoranthene.
    Carcinogenesis, 1995, Volume: 16, Issue:11

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Animals, Newborn; Benzopyrenes; Carcinogens; Chrysenes; Female; Fluorenes; Male; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Pregnancy

1995
Depression of hepatic cytochrome P450 monooxygenases after chronic environmental tobacco smoke exposure of young ferrets.
    Toxicology letters, 1995, Volume: 76, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Analysis of Variance; Animals; Benzo(a)pyrene; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Dose-Response Relationship, Drug; Down-Regulation; Environmental Exposure; Female; Ferrets; Immunoblotting; Liver; Male; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Pregnancy; Tobacco Smoke Pollution

1995
DNA adducts as biomarkers for assessing exposure to polycyclic aromatic hydrocarbons in tissues from Xuan Wei women with high exposure to coal combustion emissions and high lung cancer mortality.
    Environmental health perspectives, 1993, Volume: 99

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Air Pollutants; Benzo(a)pyrene; Biomarkers; China; Coal; DNA; DNA Damage; Environmental Exposure; Environmental Monitoring; Female; Humans; Lung Neoplasms; Male; Polycyclic Compounds; Pregnancy

1993
Exposure to environmental tobacco smoke results in an increased production of (+)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide in juvenile ferret lung homogenates.
    Journal of toxicology and environmental health, 1996, Apr-19, Volume: 47, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Carcinogens; DNA; Environmental Exposure; Female; Ferrets; Lung; Male; Pregnancy; Sex Characteristics; Stereoisomerism; Tobacco Smoke Pollution

1996
Detection of benzo[a]pyrene diol epoxide-DNA adducts in embryos from smoking couples: evidence for transmission by spermatozoa.
    Molecular human reproduction, 1999, Volume: 5, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; Blastocyst; Blastomeres; Cattle; Cotinine; Cytoplasm; DNA Adducts; Embryo, Mammalian; Embryonic Development; Female; Fertilization in Vitro; Humans; Immunohistochemistry; Male; Pregnancy; Smoking; Spermatozoa

1999
Fluorescence detection of lesions in DNA.
    Basic life sciences, 1990, Volume: 53

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Chromatography, High Pressure Liquid; DNA; DNA Adducts; DNA Damage; Female; Humans; Lymphocytes; Placenta; Polycyclic Compounds; Pregnancy; Smoking; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1990
Comparison of the formation of benzo[a]pyrene diolepoxide-DNA adducts in vitro by rat and human microsomes: evidence for the involvement of P-450IA1 and P-450IA2.
    Journal of biochemical toxicology, 1989,Summer, Volume: 4, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Enzyme Induction; Female; Humans; In Vitro Techniques; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Species Specificity; Spectrometry, Fluorescence

1989
Detection of benzo[a]pyrene diol epoxide-DNA adducts in human placenta.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:23

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Chromatography, Affinity; Chromatography, High Pressure Liquid; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Female; Gas Chromatography-Mass Spectrometry; Humans; Placenta; Pregnancy; Spectrometry, Fluorescence

1988
32P-postlabeling assay in mice of transplacental DNA damage induced by the environmental carcinogens safrole, 4-aminobiphenyl, and benzo(a)pyrene.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aminobiphenyl Compounds; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens, Environmental; Dioxoles; DNA; DNA Adducts; Female; Fetus; Kidney; Liver; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Phosphorus Radioisotopes; Placenta; Pregnancy; Safrole

1986
Adduct formation in hemoglobin of the newborn mouse exposed in utero to benzo[a]pyrene.
    Toxicology, 1985, Volume: 37, Issue:3-4

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Administration, Topical; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Body Burden; Female; Hemoglobins; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Pregnancy

1985