Compounds > 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

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7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Genetic Predisposition

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with Genetic Predisposition in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (21.05)	18.2507
2000's	11 (57.89)	29.6817
2010's	4 (21.05)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cai, Y; Cui, S; Jin, C; Lu, X; Wu, S; Xiao, M; Xue, P; Yang, J; Yu, T; Zhang, G; Zhang, L; Zhang, Q; Zheng, X	1
Hsu, TC; Wu, X; Zheng, YL	1
Li, C; Wang, LE; Wei, Q	1
Cheng, YW; Chiang, CC; Chou, MC; Lee, H; Tsai, YY; Tung, JN; Wu, HH	1
Hussain, T; Kotnis, A; Mulherkar, R; Sarin, R	1
Hong, WK; Spitz, MR; Wu, X; Zheng, YL; Zhu, Y	1
Bondy, ML; Brewster, A; Shi, Q; Singletary, SE; Wang, LE; Wei, Q	1
Chen, SY; Chen, YM; Darbha, R; Lin, JR; Lin, P; Liu, TY	1
Grossman, HB; Hazra, A; Luo, S; Spitz, MR; Wu, X; Zhu, Y	1
Agrawal, M; Kennedy, DO; Motykiewicz, G; Santella, RM; Senie, RT; Shen, J; Terry, MB; Zhang, FF	1
El-Naggar, AK; Hu, Z; Li, C; Sturgis, EM; Wang, LE; Wei, Q; Xiong, P	1
Bondy, ML; Gu, J; Hsu, TC; Sigurdson, A; Spitz, MR; Wu, X	1
Amos, CI; Spitz, MR; Xu, W	1
Herzog, C; Hu, X; Singh, SV; Zimniak, P	1
Alexandrov, K; Bartsch, H; Nair, J; Nair, U; Rojas, M	1
Coles, B; Kadlubar, FF; Lang, NP; Yang, M	1
Bosken, CH; Firozi, PF; Hong, WK; Li, D; Spitz, MR; Wang, LE; Wei, Q	1
Bondy, ML; Li, D; Shen, H; Singletary, SE; Spitz, MR; Wang, LE; Wei, Q; Xiong, P	1
Hong, WK; Lee, JJ; Lippman, SM; Spitz, MR; Thomas, M; Wei, QV; Wu, X; Zhu, Y	1

Reviews

2 review(s) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Genetic Predisposition

Article	Year
DNA repair phenotype and cancer susceptibility--a mini review. International journal of cancer, 2009, Mar-01, Volume: 124, Issue:5 Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; DNA Adducts; DNA Repair; Genetic Predisposition to Disease; Humans; Mutagens; Neoplasms; Phenotype; Protein Array Analysis; Ultraviolet Rays	2009
Is there a genetic basis for lung cancer susceptibility? Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1999, Volume: 151 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bleomycin; DNA Adducts; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Molecular Epidemiology; Risk Factors	1999

Other Studies

17 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Genetic Predisposition

Article	Year
Rs3212986 polymorphism, a possible biomarker to predict smoking-related lung cancer, alters DNA repair capacity via regulating ERCC1 expression. Cancer medicine, 2018, Volume: 7, Issue:12 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Aged, 80 and over; Biomarkers; Carcinogens; Cell Line; DNA Repair; DNA-Binding Proteins; Endonucleases; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Smoking	2018
Mutagen sensitivity as measured by induced chromatid breakage as a marker of cancer risk. Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1105 Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bleomycin; Cells, Cultured; Chromatids; DNA Breaks, Double-Stranded; Genetic Markers; Genetic Predisposition to Disease; Humans; Lymphocytes; Mutagens; Neoplasms; Quinolones; Radiation Injuries; Risk	2014
An association between BPDE-like DNA adduct levels and CYP1A1 and GSTM1 polymorphisma in pterygium. Molecular vision, 2010, Apr-08, Volume: 16 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aged; Aged, 80 and over; Cytochrome P-450 CYP1A1; DNA Adducts; Epithelial Cells; Female; Genetic Predisposition to Disease; Glutathione Transferase; Humans; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pterygium; Risk Factors; Sex Characteristics	2010
Genetic susceptibility to multiple primary neoplasms in the upper aero-digestive tract: genotype score and phenotype correlation. Cancer letters, 2013, May-10, Volume: 332, Issue:1 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Apoptosis; Carcinogens; Case-Control Studies; Cell Cycle Checkpoints; Cell Line, Transformed; Cell Line, Tumor; DNA Damage; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene-Environment Interaction; Genetic Association Studies; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Logistic Models; Lymphocytes; Male; Middle Aged; Models, Genetic; Mutagenicity Tests; Neoplasms, Multiple Primary; Phenotype; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors	2013
BPDE-induced lymphocytic 3p21.3 aberrations may predict head and neck carcinoma risk. Cancer, 2002, Aug-01, Volume: 95, Issue:3 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aged; Carcinogens; Carcinoma, Squamous Cell; Chromosome Aberrations; Chromosomes, Human, Pair 3; Female; Genetic Predisposition to Disease; Genetic Testing; Head and Neck Neoplasms; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Middle Aged; Predictive Value of Tests	2002
Reduced DNA repair of benzo[a]pyrene diol epoxide-induced adducts and common XPD polymorphisms in breast cancer patients. Carcinogenesis, 2004, Volume: 25, Issue:9 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Breast Neoplasms; Carcinogens; Case-Control Studies; DNA Adducts; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Genotype; Humans; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proteins; Risk Factors; Transcription Factors; Xeroderma Pigmentosum Group D Protein	2004
Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway. Cancer research, 2004, May-15, Volume: 64, Issue:10 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Active Transport, Cell Nucleus; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cytochrome P-450 CYP1A1; DNA Adducts; Enzyme Induction; Genetic Predisposition to Disease; Glycine N-Methyltransferase; Humans; Inactivation, Metabolic; Liver Neoplasms; Methyltransferases; Models, Molecular; Transfection	2004
Benzo[a]pyrene diol epoxide-induced 9p21 aberrations associated with genetic predisposition to bladder cancer. Genes, chromosomes & cancer, 2004, Volume: 41, Issue:4 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aged; Chromosome Aberrations; Chromosomes, Human, Pair 9; Female; Genetic Predisposition to Disease; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Middle Aged; Mutagens; Pilot Projects; Smoking; Urinary Bladder Neoplasms	2004
DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer. Journal of the National Cancer Institute, 2005, Jan-19, Volume: 97, Issue:2 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Analysis of Variance; Breast Neoplasms; Carcinogens; Case-Control Studies; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Female; Fluorescent Antibody Technique, Direct; Genetic Predisposition to Disease; Humans; Logistic Models; Lymphocytes; Mutagens; Odds Ratio; Siblings	2005
In vitro benzo[a]pyrene diol epoxide-induced DNA damage and chromosomal aberrations in primary lymphocytes, smoking, and risk of squamous cell carcinoma of the head and neck. International journal of cancer, 2007, Dec-15, Volume: 121, Issue:12 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Chromosome Aberrations; Comet Assay; DNA Damage; DNA Repair; Female; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Lymphocytes; Male; Middle Aged; Mutagens; Odds Ratio; Risk Assessment; Risk Factors; Smoking; Texas	2007
Three measures of mutagen sensitivity in a cancer-free population. Cancer genetics and cytogenetics, 1999, Volume: 110, Issue:1 Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Bleomycin; DNA Damage; Female; Genetic Predisposition to Disease; Humans; Lymphocytes; Male; Middle Aged; Mutagens; Neoplasms	1999
Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. Cancer research, 1999, May-15, Volume: 59, Issue:10 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Air Pollutants; Alleles; Amino Acid Substitution; Carcinogens, Environmental; Carcinoma, Squamous Cell; DNA Adducts; DNA Damage; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Laryngeal Neoplasms; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured	1999
Genetic cancer susceptibility and DNA adducts: studies in smokers, tobacco chewers, and coke oven workers. Cancer detection and prevention, 1999, Volume: 23, Issue:6 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Biomarkers, Tumor; Cytochrome P-450 CYP1A1; DNA Adducts; DNA, Neoplasm; Genetic Predisposition to Disease; Glutathione Transferase; Humans; Leukocytes; Leukoplakia; Lung Neoplasms; Male; Occupational Exposure; Plants, Toxic; Polycyclic Aromatic Hydrocarbons; Polymerase Chain Reaction; Retrospective Studies; Smoking; Tobacco, Smokeless	1999
Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide. Cancer letters, 2000, Aug-11, Volume: 156, Issue:2 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alleles; Carcinogens; Catalysis; Dinitrochlorobenzene; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Inactivation, Metabolic; Individuality; Isoenzymes; Kinetics; Lung; Pyridines; Recombinant Proteins; Substrate Specificity	2000
Sensitivity to DNA damage induced by benzo(a)pyrene diol epoxide and risk of lung cancer: a case-control analysis. Cancer research, 2001, Feb-15, Volume: 61, Issue:4 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Carcinogens; Case-Control Studies; DNA Adducts; DNA Damage; DNA Repair; Female; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Middle Aged	2001
Sensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study. Cancer research, 2001, Dec-01, Volume: 61, Issue:23 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Breast Neoplasms; Carcinogens; Case-Control Studies; Chromosome Aberrations; Cocarcinogenesis; Female; Genetic Predisposition to Disease; Glutathione Transferase; Humans; Middle Aged; Pilot Projects; Polymorphism, Genetic	2001
Chromosome instability in lymphocytes: a potential indicator of predisposition to oral premalignant lesions. Cancer research, 2002, May-15, Volume: 62, Issue:10 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bleomycin; Case-Control Studies; Chromosome Aberrations; Chromosomes, Human, Pair 3; Erythroplasia; Female; Genetic Predisposition to Disease; Humans; In Situ Hybridization, Fluorescence; Leukoplakia, Oral; Lymphocytes; Male; Middle Aged; Mutagens; Smoking	2002