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7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Experimental Neoplasms

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with Experimental Neoplasms in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's5 (41.67)18.2507
2000's3 (25.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greenlee, AR; Jiang, Y; Liu, L; Shen, Y; Tan, A; Yang, Q; Zhou, L1
Cao, G; Ding, J; Gong, W; Han, T; He, G; Huang, L; Huang, S; Liang, J; Ning, B; Sun, W; Wang, H; Wen, W; Wu, K; Wu, M; Xie, W1
Greenlee, AR; Han, Z; Jiang, Y; Li, X; Wu, J; Wu, Y; Zhao, Y1
Feng, SM; Ji, WD; Jiang, YG; Wang, M1
Pelling, JC; Slaga, TJ1
Amin, S; Dai, W; Desai, D; Harvey, RG; Hecht, SS1
Israels, ED; Israels, LG1
Boucher, DM; Iannaccone, PM1
Balansky, RM; Coscia, N; D'Agostini, F; De Flora, S; Izzotti, A; Scatolini, L1
Ji, C; Marnett, LJ; Pruess-Schwartz, D; Reddy, A1
Collins, JL; Vanderslice, WE1
Chang, RL; Conney, AH; Huang, MT; Jerina, DM; Sayer, JM; Wood, AW; Yagi, H1

Reviews

1 review(s) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Experimental Neoplasms

ArticleYear
Observations on vitamin K deficiency in the fetus and newborn: has nature made a mistake?
    Seminars in thrombosis and hemostasis, 1995, Volume: 21, Issue:4

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; Biotransformation; Carcinogens; Chick Embryo; Cocarcinogenesis; DNA Adducts; Female; Fetal Diseases; Fetus; Humans; Infant, Newborn; Liver; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms; Neoplasms, Experimental; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Smoking; Vitamin K; Vitamin K 1; Vitamin K Deficiency; Warfarin; Xenobiotics

1995

Other Studies

11 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Experimental Neoplasms

ArticleYear
Silencing of N-Ras gene expression using shRNA decreases transformation efficiency and tumor growth in transformed cells induced by anti-BPDE.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 105, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Blotting, Western; Carcinogens; Cell Cycle; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection; Tumor Stem Cell Assay; Up-Regulation

2008
Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
    The Journal of biological chemistry, 2009, Nov-27, Volume: 284, Issue:48

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antibiotics, Antineoplastic; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Cyclin D1; Epithelial Cells; Gene Expression; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Nude; Models, Biological; Mutation; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Signal Transduction; Sirolimus

2009
miR-106a-mediated malignant transformation of cells induced by anti-benzo[a]pyrene-trans-7,8-diol-9,10-epoxide.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 119, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Down-Regulation; Flow Cytometry; Humans; Mice; Mice, Nude; MicroRNAs; Neoplasm Transplantation; Neoplasms, Experimental; Oligonucleotides, Antisense; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Up-Regulation

2011
[Antitransforming activity of chlorophyllin against trans-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2003, Volume: 37, Issue:5

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Chlorophyllides; Mice; Mice, Inbred BALB C; Neoplasms, Experimental

2003
Comparison of levels of benzo[a]pyrene diol epoxide diastereomers covalently bound in vivo to macromolecular components of the whole epidermis versus the basal cell layer.
    Carcinogenesis, 1982, Volume: 3, Issue:10

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Carcinogens; DNA; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship

1982
Tumorigenicity in newborn mice of fjord region and other sterically hindered diol epoxides of benzo[g]chrysene, dibenzo[a,l]pyrene (dibenzo[def,p]chrysene), 4H-cyclopenta[def]chrysene and fluoranthene.
    Carcinogenesis, 1995, Volume: 16, Issue:11

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Animals, Newborn; Benzopyrenes; Carcinogens; Chrysenes; Female; Fluorenes; Male; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Pregnancy

1995
Overexpression of human glutathione S-transferase pi protects NIH 3T3 cells against (+/-)anti BPDE cytotoxicity but not tumor formation.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1995, Volume: 63, Issue:4

    Topics: 3T3 Cells; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Carcinogens; Glutathione Transferase; Humans; Isoenzymes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Stereoisomerism; Transfection

1995
Chemoprevention of smoke-related DNA adduct formation in rat lung and heart.
    Carcinogenesis, 1992, Volume: 13, Issue:11

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetylcysteine; Animals; Carcinogens; DNA; Heart; Lung; Male; Neoplasms, Experimental; Nicotiana; Plants, Toxic; Rats; Rats, Sprague-Dawley; Smoke

1992
Oxidation of polycyclic hydrocarbons by oxygen radicals.
    Princess Takamatsu symposia, 1990, Volume: 21

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Female; Free Radicals; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oxidation-Reduction; Polycyclic Compounds; Skin Neoplasms; Tetradecanoylphorbol Acetate

1990
Anti-tumor surveillance of non-contact-inhibited transformed cell lines.
    International journal of cancer, 1988, Sep-15, Volume: 42, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Transformed; Cell Transformation, Neoplastic; Histocompatibility Antigens; Immunity, Cellular; Immunologic Surveillance; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phenotype

1988
Inhibitory effect of 3-hydroxybenzo(a)pyrene on the mutagenicity and tumorigenicity of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Biotransformation; Cricetinae; Kinetics; Mice; Mutagenicity Tests; Mutation; Neoplasms, Experimental; Polycyclic Compounds; Salmonella typhimurium; Skin Neoplasms; Structure-Activity Relationship

1986