7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with Cell Transformation, Neoplastic in 64 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 19 (29.69) | 18.7374 |
1990's | 8 (12.50) | 18.2507 |
2000's | 21 (32.81) | 29.6817 |
2010's | 15 (23.44) | 24.3611 |
2020's | 1 (1.56) | 2.80 |
Authors | Studies |
---|---|
Chen, K; Chen, X; Jiang, Y; Li, M; Li, W; Ling, Y; Lu, X; Xiao, Z; Xu, M; Yang, Z | 1 |
Jiang, Y; Liu, H; Peng, B; Wu, J; Xu, E; Yang, Q; Zhang, S | 1 |
Chen, G; Chen, L; Fu, K; Gao, J; Huang, C; Huang, H; Jin, H; Li, J; Li, Y; Liu, P; Liu, Y; Pan, X; Yang, C; Zeng, X; Zhang, L; Zhu, J | 1 |
Amin, S; Chen, W; Desai, D; Krzeminski, J; Lin, Y; Padilla, MT; Xu, X | 1 |
Greenlee, AR; Jiang, Y; Liu, L; Shen, Y; Tan, A; Yang, Q; Zhou, L | 1 |
Jiang, Y; Shen, Y; Tan, A; Zhou, L | 1 |
Chu, M; Deng, L; Fu, J; Huang, H; Liu, S; Wang, Y; Xu, L; Zhang, L; Zhang, X; Zhou, Z; Zhu, Y | 1 |
Chen, L; Chen, W; Ji, W; Lai, Y; Li, D; Li, W; Lin, Y; Ma, R; Pang, Y; Tang, S; Wang, Q; Wei, Q; Xiao, Y; Yang, P; Zheng, Y; Zhuang, Z | 1 |
Fukasawa, K; Igarashi, H; Iwaizumi, M; Nagura, K; Shinmura, K; Sugimura, H; Suzuki, M; Yamada, H | 1 |
Chen, X; Duan, H; Fu, J; Greenlee, AR; Jiang, Y; Shen, Y | 1 |
Chen, LP; Chen, W; Lai, YD; Li, DC; Li, WX; Lin, YC; Lin, ZN; Ma, RL; Pang, YQ; Tang, SF; Wang, Q; Wei, Q; Xiao, YM; Yang, P | 1 |
Greenlee, AR; Jiang, YG; Liu, LH; Shen, YL; Zhou, LL | 1 |
Cao, G; Ding, J; Gong, W; Han, T; He, G; Huang, L; Huang, S; Liang, J; Ning, B; Sun, W; Wang, H; Wen, W; Wu, K; Wu, M; Xie, W | 1 |
Duan, H; Jiang, Y; Wu, Y; Zhang, H | 1 |
Greenlee, AR; Han, Z; Jiang, Y; Liu, L; Zhang, H | 1 |
Kumar, S; Mukherjee, JJ | 1 |
Cai, S; Du, J; Jiang, J; Liu, L; Liu, Q; Sung, KL; Yan, X; Yang, L; Yang, Y; Yu, S; Zhang, H | 1 |
Drouin, R; Lacoste, S; Rochette, PJ | 1 |
Fu, J; Huang, H; Wang, Y; Yao, B; Ying, X; Yuan, Z; Zhang, L; Zhao, P; Zhong, W; Zhou, Z | 1 |
Amin, S; Blake, DC; Gallagher, CJ; Herzog, CR; Jones, NR; Lazarus, P; Mikse, OR; Sun, YW; Weisz, J | 1 |
Greenlee, AR; Han, Z; Jiang, Y; Li, X; Wu, J; Wu, Y; Zhao, Y | 1 |
Gocinski, R; Kumar, S; Mukherjee, JJ; Williams, J | 1 |
Greenlee, AR; Jiang, Y; Li, Y; Liu, H; Wu, J; Yang, C; Zhao, Y | 1 |
Jiang, YG; Li, YQ; Liu, HY; Zhao, Y | 1 |
Bai, L; Belinsky, SA; Chen, W; Gott, KM; Leng, S; Lin, Y; Padilla, MT; Scott, BR; Tellez, CS; Wilder, JA; Xu, X | 1 |
Chen, J; Chen, X; Jiang, Y | 1 |
Feng, SM; Ji, WD; Jiang, YG; Wang, M | 1 |
Chen, JK; He, M; Ji, WD; Jiang, YG; Lü, JC; Shi, LY; Wu, ZL; Zeng, BH | 1 |
An, S; Chen, J; Chen, X; Liu, L; Zhao, Y | 1 |
Burke, TJ; Campian, JL; Clark, DR; Eaton, JW; Gao, X; McGregor, WG; Qian, M | 1 |
An, SJ; Chen, JK; Chen, XM; Liu, LL; Zhao, YF | 1 |
An, SJ; Chang, W; Chen, HJ; Chen, JK; Chen, XM; Jiang, YG; Wei, QY | 1 |
Bin, XN; Chen, XM; Fu, J; Jiang, YG | 1 |
Amin, S; Desai, D; Ding, M; Hu, Y; Huang, C; Li, J; Lu, Y; Ouyang, W; Qu, Q; Song, L; Yan, Y; Zhang, D | 1 |
Bansal, P; Lazo, JS; Oguri, T; Singh, SV; Srivastava, SK | 1 |
Cao, H; Fu, J; Jiang, YG; Shen, YL; Zhou, LL | 1 |
Callaham, MF; Huberman, E; Jones, CA | 1 |
Kakunaga, T; Lo, K | 1 |
Chang, GT; Harvey, RG; Weiss, SB | 1 |
Lockhart, ML; Rosenberg, BH | 1 |
Cerutti, P; Zimmerman, R | 1 |
Connell, JR | 1 |
Engelhardt, U; Moeroey, T; Schaefer-Ridder, M | 1 |
Jeffrey, AM; Milo, GE; Tejwani, R | 1 |
Backer, JM; Boerzig, M; Weinstein, IB | 1 |
Bauer, B; Caamano, J; Harris, CC; Iizasa, T; Klein-Szanto, AJ; Lechner, J; Metcalf, R; Momiki, S | 1 |
Doehmer, J; Doss, AJ; Fields, WR; Haynes, RL; Li, Y; Morrow, CS; Townsend, AJ | 1 |
Anderson, LM; Khan, QA | 1 |
Kohler, SK; Louden, C; Maher, VM; McCormick, JJ; Reinhold, DS; Yang, D | 1 |
Wong, JL; Yuan, B | 1 |
Boyer, JC; Cordeiro-Stone, M; Kaufmann, WK | 1 |
Collins, JL; Vanderslice, WE | 1 |
Krolewski, B; Little, JB; Reynolds, RJ | 1 |
Kurian, P; Milo, GE; Ribovich, ML | 1 |
Krolewski, B; Little, JB; Nagasawa, H | 1 |
Ernst, SM; Hixson, DC; Nairn, RS; Patskan, G; Pelling, JC; Rhode, SL; Slaga, TJ | 1 |
He, MC; Zhang, L | 1 |
Shay, JW; Werbin, H | 1 |
Fahl, WE; Manoharan, TH; Stevens, CW | 1 |
Krolewski, B; Little, JB | 1 |
Jeffrey, AM; Kurian, P; Milo, GE | 1 |
Kaufmann, WK | 1 |
Bell, WN; Grisham, JW; Smith, GJ | 1 |
Kumari, HL; Kurian, P; Milo, GE | 1 |
2 review(s) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Cell Transformation, Neoplastic
Article | Year |
---|---|
[Mapping DNA damage to understand somatic mutagenesis].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aflatoxin B1; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Codon; DNA; DNA Damage; DNA Methylation; DNA Repair; Genes, p53; Humans; Liver Neoplasms; Lung Neoplasms; Mutagenesis; Neoplasms, Radiation-Induced; Polymerase Chain Reaction; Skin Neoplasms; Sunlight; Ultraviolet Rays | 2010 |
Cell cycle checkpoints and DNA repair preserve the stability of the human genome.
Topics: Animals; Ataxia Telangiectasia; Benzopyrenes; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA Repair; Gene Expression Regulation; Genes, p53; Genome, Human; Humans; Neoplasms; Neoplasms, Radiation-Induced; Rats; Replicon; Tumor Suppressor Protein p53 | 1995 |
62 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Cell Transformation, Neoplastic
Article | Year |
---|---|
The Circ_CARM1 controls cell migration by regulating CTNNBIP1 in anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide-transformed 16HBE cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adaptor Proteins, Signal Transducing; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; RNA, Circular | 2021 |
Oncogenic role of long noncoding RNA AF118081 in anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide-transformed 16HBE cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Apoptosis; Bronchi; Carcinogens; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene Knockdown Techniques; Humans; Lung Neoplasms; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Oncogenes; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; RNA Interference; RNA, Long Noncoding | 2014 |
PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE Exposure.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Carcinogenesis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Lung Neoplasms; Mice; MicroRNAs; Phosphoprotein Phosphatases | 2015 |
Quercetin inhibits multiple pathways involved in interleukin 6 secretion from human lung fibroblasts and activity in bronchial epithelial cell transformation induced by benzo[a]pyrene diol epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cell Line; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Epithelial Cells; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Lung; MAP Kinase Signaling System; Quercetin; Signal Transduction; STAT3 Transcription Factor | 2016 |
Silencing of N-Ras gene expression using shRNA decreases transformation efficiency and tumor growth in transformed cells induced by anti-BPDE.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Blotting, Western; Carcinogens; Cell Cycle; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection; Tumor Stem Cell Assay; Up-Regulation | 2008 |
[Study on expression of Ras family gene in transformed cells induced by BPDE].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bronchi; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Genes, ras; Humans; ras Proteins; RNA, Messenger | 2008 |
TPX2 in malignantly transformed human bronchial epithelial cells by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Apoptosis; Blotting, Western; Bronchi; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Databases, Protein; Electrophoresis, Gel, Two-Dimensional; Epithelial Cells; Gene Expression; Humans; Immunohistochemistry; Immunoprecipitation; Isoelectric Focusing; Microtubule-Associated Proteins; Mutagens; Nuclear Proteins; Phosphorylation; RNA Interference; RNA, Small Interfering; Sister Chromatid Exchange; Tyrosine | 2008 |
Development of human cell models for assessing the carcinogenic potential of chemicals.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aflatoxin B1; Animals; Benzo(a)pyrene; Bronchi; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytochrome P-450 CYP1A1; Genes, myc; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Nickel | 2008 |
Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE).
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aged; Cell Cycle; Cell Transformation, Neoplastic; Centrosome; Chi-Square Distribution; Chromosomal Instability; DNA Adducts; DNA-Directed DNA Polymerase; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Gene Expression Profiling; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Lung Neoplasms; Male; Middle Aged; Mutagens; Oligonucleotide Array Sequence Analysis; Tumor Suppressor Protein p53 | 2008 |
Effects of silencing of HER2/neu gene in anti-BPDE-transformed cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bronchi; Cell Cycle; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Epithelial Cells; Genes, erbB-2; Humans; Mutagens; Receptor, ErbB-2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stem Cells; Transfection | 2009 |
[Establishment and application of oncogene over expressed human epithelial cell transformation model].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression; Gene Expression Regulation; Genes, myc; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Mice, Nude | 2008 |
MicroRNA expression profiles and miR-10a target in anti-benzo[a] pyrene-7, 8-diol-9, 10-epoxide-transformed human 16HBE cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Profiling; Homeodomain Proteins; Humans; MicroRNAs; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2009 |
Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antibiotics, Antineoplastic; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Cyclin D1; Epithelial Cells; Gene Expression; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Nude; Models, Biological; Mutation; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Signal Transduction; Sirolimus | 2009 |
MiR-320 and miR-494 affect cell cycles of primary murine bronchial epithelial cells exposed to benzo[a]pyrene.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Bronchi; Carcinogens; Cell Cycle; Cell Separation; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase 6; Environmental Pollutants; Epithelial Cells; Female; Flow Cytometry; Male; Mice; MicroRNAs; Rats; Reverse Transcriptase Polymerase Chain Reaction; Transfection | 2010 |
Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Apoptosis; Blotting, Western; Carcinogens; Cell Line, Transformed; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2010 |
Phenolic fraction of tobacco smoke condensate potentiates benzo[a]pyerene diol epoxide-induced cell transformation: role of protein kinase C.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Drug Synergism; Humans; NF-kappa B; Protein Kinase C; Tobacco Smoke Pollution; Transcription Factor AP-1 | 2010 |
Targeting eradication of malignant cells derived from human bone marrow mesenchymal stromal cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; Antigens, CD; Antimetabolites; Aspartic Acid; Bone Marrow Cells; Cell Differentiation; Cell Survival; Cell Transformation, Neoplastic; Cytosine Deaminase; Escherichia coli Proteins; Flucytosine; Gene Expression; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Kruppel-Like Transcription Factors; Lentivirus; Luciferases; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Phosphonoacetic Acid; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Response Elements; Stromal Cells; Telomerase; Transduction, Genetic; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays; Young Adult | 2010 |
Antigen-subtracted 2-DE/MS strategy, a novel proteomic analysis platform.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antigens; Bronchi; Cell Line, Transformed; Cell Transformation, Neoplastic; Electrophoresis, Gel, Two-Dimensional; Epithelial Cells; Humans; Immunoprecipitation; Mass Spectrometry; Proteomics; Rabbits | 2011 |
FOXO3 encodes a carcinogen-activated transcription factor frequently deleted in early-stage lung adenocarcinoma.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Deletion; Genes, Tumor Suppressor; Humans; Lung Neoplasms; RNA, Messenger; Transcriptional Activation | 2010 |
miR-106a-mediated malignant transformation of cells induced by anti-benzo[a]pyrene-trans-7,8-diol-9,10-epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Down-Regulation; Flow Cytometry; Humans; Mice; Mice, Nude; MicroRNAs; Neoplasm Transplantation; Neoplasms, Experimental; Oligonucleotides, Antisense; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Up-Regulation | 2011 |
Phenolic fraction of tobacco smoke inhibits BPDE-induced apoptosis response and potentiates cell transformation: role of attenuation of p53 response.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Carcinogens; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Mice; NF-kappa B; Nicotiana; Phenols; Smoke; Tumor Suppressor Protein p53 | 2011 |
The role of miR-506 in transformed 16HBE cells induced by anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Bronchi; Carcinogens; Cell Adhesion; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Neoplasm Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Respiratory Mucosa; Resting Phase, Cell Cycle; Tumor Burden; Xenograft Model Antitumor Assays | 2011 |
[Effect of miR-542-3p on carcinogenesis induced by anti-benzo(a) pyrene-7,8-diol-9,10-epoxide].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bronchi; Cell Transformation, Neoplastic; Epithelial Cells; Humans; MicroRNAs; Transfection | 2011 |
Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarette-smoke carcinogen.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bronchi; Carcinogens; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; Epithelial Cells; Fibroblasts; Gamma Rays; Humans; Interleukin-6; Lung; MAP Kinase Signaling System; NF-kappa B; Nicotiana; Smoke | 2012 |
[Malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene metabolite dihydroxyepoxy benzo pyrene].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Bronchi; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Humans | 2001 |
[Antitransforming activity of chlorophyllin against trans-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Chlorophyllides; Mice; Mice, Inbred BALB C; Neoplasms, Experimental | 2003 |
[Study on lung carcinogenesis associated genes in human lung squamous cell carcinoma and malignant transformation of human bronchial epithelial cells induced by carcinogen].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bronchi; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Lung Neoplasms; Nickel; Oligonucleotide Array Sequence Analysis | 2003 |
[Gene expression differences between the anti-BPDE-transformed and normal cells by suppression subtractive hybridization].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Carcinogens; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Nucleic Acid Hybridization; Polymerase Chain Reaction | 2004 |
Cytotoxic and mutagenic effects of tobacco-borne free fatty acids.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; Fatty Acids, Nonesterified; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransferase; Iron; Lung; Mice; Mutagens; Mutation; Nicotiana; NIH 3T3 Cells; Phenotype | 2006 |
Over-expressed genes detected by suppression subtractive hybridization in carcinoma derived from transformed 16HBE cells induced by BPDE.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Carcinogens; Carcinoma; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Nucleic Acid Hybridization; Polymerase Chain Reaction; RNA, Messenger | 2005 |
Characterization of 67 kD laminin receptor, a protein whose gene is overexpressed on treatment of cells with anti-benzo[a]pyrene-7,8-diol-9,10-epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Base Sequence; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Molecular Sequence Data; Receptors, Laminin; RNA; Sequence Analysis, RNA; Transfection | 2006 |
[Study on E-cadherin, Cyclin D1 and Cyclin E expression in anti-malignant transformation by chlorophyllin].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Antimutagenic Agents; Cadherins; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chlorophyllides; Cyclin D1; Cyclin E; Epithelial Cells; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Direct evidence for the critical role of NFAT3 in benzo[a]pyrene diol-epoxide-induced cell transformation through mediation of inflammatory cytokine TNF induction in mouse epidermal Cl41 cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epidermis; Female; Genes, Reporter; Genetic Vectors; Mice; Mice, Nude; NFATC Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2007 |
Cell division cycle 25B phosphatase is essential for benzo(a)pyrene-7,8-Diol-9,10-epoxide induced neoplastic transformation.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Carcinogens; cdc25 Phosphatases; Cell Cycle Proteins; Cell Transformation, Neoplastic; Checkpoint Kinase 1; DNA Damage; Enzyme Induction; Female; Fibroblasts; Humans; Lung; Male; Mice; Mice, Inbred A; Mice, Nude; Protein Kinases | 2007 |
[MicroRNA profiles of malignantly transformed cells induced by anti-benzo-a-pyrene-trans-7, 8-dihydrodiol-9, 10-epoxide].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bronchi; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Gene Expression Profiling; Humans; MicroRNAs | 2008 |
Enhancement of chemical-carcinogen-induced cell transformation in hamster embryo cells by 1 alpha,25-dihydroxycholecalciferol, the biologically active metabolite of vitamin D3.
Topics: 24,25-Dihydroxyvitamin D 3; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Calcitriol; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cholecalciferol; Cricetinae; Dihydroxycholecalciferols; Embryo, Mammalian; Female; Mesocricetus; Methylnitronitrosoguanidine; Pregnancy | 1984 |
Only one type of benzo(a) pyrene-DNA adduct is detected in transformable mouse cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Repair; Humans | 1981 |
The fate of SV40 DNA in infected cells after treatment with benzo(a)pyrene diol epoxide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Chlorocebus aethiops; DNA Replication; DNA, Viral; Kidney; Male; Mutagens; Simian virus 40; Thymidine; Virus Replication | 1981 |
Inhibition of DNA synthesis, independent of DNA adduct formation, by benzo[a]pyrene diol epoxide in mammalian cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chlorocebus aethiops; DNA; DNA Replication; DNA, Viral; Kidney; Kinetics; Simian virus 40; Virus Replication | 1983 |
Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Gamma Rays; Mice; Mice, Inbred C3H; Oxygen; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1984 |
Karyotype analysis of carcinogen-treated Chinese hamster cells in vitro evolving from a normal to a malignant phenotype.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Agar; Animals; Benzopyrenes; Carcinogens; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Cricetinae; Cricetulus; Dihydroxydihydrobenzopyrenes; Fetus; Karyotyping; Lung; Sarcoma, Experimental | 1984 |
Inactivation of the thymidine kinase gene after in vitro modification with benzo(a)pyrene-diol-epoxide and transfer to LTK- cells as a eukaryotic test for carcinogens.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; DNA, Recombinant; Genes; L Cells; Mice; Nucleic Acid Hybridization; Plasmids; Thymidine Kinase | 1984 |
Benzo[a]pyrene diol epoxide DNA adduct formation in transformable and non-transformable human foreskin fibroblast cells in vitro.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Fibroblasts; Humans; Infant, Newborn; Male; Skin | 1982 |
When do carcinogen-treated 10T1/2 cells acquire the commitment to form transformed foci?
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Drug Resistance; Mice; Ouabain; Time Factors | 1982 |
Invasive tumors derived from xenotransplanted, immortalized human cells after in vivo exposure to chemical carcinogens.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Animals; Bronchi; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Epithelium; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Pyrenes; Rats; Rats, Inbred F344; Tracheal Neoplasms; Transplantation, Heterologous | 1993 |
Chemoprotective functions of glutathione S-transferases in cell lines induced to express specific isozymes by stable transfection.
Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylation; Animals; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Gene Expression; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoenzymes; Mice; Neoplasms; Rats; Transfection | 1998 |
Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Antineoplastic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chrysenes; Dactinomycin; DNA Damage; Epithelial Cells; Flow Cytometry; G1 Phase; Genes, p53; Humans; Lung; Lung Neoplasms; Mice; Mutagens; Mutation; Nocodazole; Nucleic Acid Synthesis Inhibitors; Tumor Cells, Cultured | 2001 |
Malignant transformation of human fibroblast cell strain MSU-1.1 by (+-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo [a]pyrene.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Calcium; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Fibroblasts; Growth Substances; Humans | 1992 |
Inactivity of acrylonitrile epoxide to modify a Ha-ras DNA in a non-focus transfection-transformation assay.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Blotting, Southern; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA; Ethylene Oxide; Genes, ras; Humans; Methylnitrosourea; Plasmids; Proto-Oncogene Mas; Transfection; Transformation, Genetic | 1991 |
Role of postreplication repair in transformation of human fibroblasts to anchorage independence.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cell Adhesion; Cell Transformation, Neoplastic; DNA Repair; DNA Replication; Humans; Xeroderma Pigmentosum | 1991 |
Anti-tumor surveillance of non-contact-inhibited transformed cell lines.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Transformed; Cell Transformation, Neoplastic; Histocompatibility Antigens; Immunity, Cellular; Immunologic Surveillance; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phenotype | 1988 |
Effect of duration of exposure to benzo(a)pyrene diol-epoxide on neoplastic transformation, mutagenesis, cytotoxicity, and total covalent binding to DNA of rodent cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Kinetics; Mice; Mice, Inbred C3H; Mutagens; Mutation; Time Factors | 1988 |
Specific BPDE I modification of replicating and parental DNA from early S phase human foreskin fibroblasts.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Adducts; DNA Replication; Fibroblasts; Humans; Interphase; Male; Methylation; Nucleotides | 1986 |
Effect of aliphatic amides on oncogenic transformation, sister chromatid exchanges, and mutations induced by cyclopenta[cd]-pyrene and benzo[a]pyrene.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetamides; Allylisopropylacetamide; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; Mutation; Pyrenes; Sister Chromatid Exchange | 1986 |
Altered expression of oncogenes in mouse epidermis following exposure to benzo(a)pyrene diol epoxides.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Transformation, Neoplastic; Dihydroxydihydrobenzopyrenes; DNA, Neoplasm; Female; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Oncogenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
[In vitro studies on the cocarcinogenic activity of CSC-NF to the tracheal epithelium of hamsters].
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cricetinae; Epithelium; Mesocricetus; Organ Culture Techniques; Smoking; Trachea | 1987 |
Cytoplasmic suppression of tumorigenicity in reconstructed mouse cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Culture Techniques; Dihydroxydihydrobenzopyrenes; Hybrid Cells; Mice | 1988 |
Characterization of mutagen-activated cellular oncogenes that confer anchorage independence to human fibroblasts and tumorigenicity to NIH 3T3 cells: sequence analysis of an enzymatically amplified mutant HRAS allele.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Base Sequence; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA, Neoplasm; Genes, ras; Humans; Mice; Molecular Sequence Data; Mutagens | 1988 |
Influence of isopropylvaleramide and allylisopropylacetamide on transformation of C3H/10T1/2 cells induced by benzo[a]pyrene derivatives.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetamides; Allylisopropylacetamide; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplastic; Dihydroxydihydrobenzopyrenes; Mice; Mice, Inbred C3H | 1985 |
Preferential binding of benzo[a]pyrene diol epoxide to the linker DNA of human foreskin fibroblasts in S phase in the presence of benzamide.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzamides; Benzopyrenes; Binding Sites; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Fibroblasts; Humans; Interphase; Skin | 1985 |
Clonal analysis of the expression of multiple transformation phenotypes and tumorigenicity by morphologically transformed 10T1/2 cells.
Topics: Animals; Bayes Theorem; Benzopyrenes; Cell Division; Cell Separation; Cell Transformation, Neoplastic; Clone Cells; DNA, Neoplasm; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Mice, Nude; Phenotype | 1993 |
Selective inhibition of the BPDE-I-induced modification of the replicating DNA of S-phase cells, by benzamide and 3-aminobenzamide.
Topics: Benzamides; Benzopyrenes; Cell Transformation, Neoplastic; DNA; Fibroblasts; Humans; S Phase | 1992 |