Compounds > 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
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7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Carcinoma, Squamous Cell

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with Carcinoma, Squamous Cell in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's10 (66.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baumeister, P; Harréus, U; Reiter, M; Schwenk-Zieger, S; Welz, C1
Baumeister, P; Harréus, U; Heinrich, K; Märte, M; Reiter, M; Schwenk-Zieger, S1
Hong, WK; Spitz, MR; Wu, X; Zheng, YL; Zhu, Y1
Albert, PS; Dawsey, SM; Divi, RL; Dong, ZW; Kleiner, DE; Olivero, OA; Poirier, MC; Qiao, YL; Roth, MJ; Schrager, JA; Taylor, PR; van Gijssel, HE; Wang, GQ1
Lazo, JS; Nemoto, K; Oguri, T; Singh, SV1
Chen, JK; He, M; Ji, WD; Jiang, YG; Lü, JC; Shi, LY; Wu, ZL; Zeng, BH1
Alexandrov, K; Cascorbi, I; Grosdidier, G; Marie, B; Martinet, N; Rojas, M; Siat, J; Vignaud, JM1
An, SJ; Chang, W; Chen, HJ; Chen, JK; Chen, XM; Jiang, YG; Wei, QY1
Cao, L; Jiang, Y; Liang, ZD; Wu, TT; Xu, XC; Zhang, H1
El-Naggar, AK; Hu, Z; Li, C; Sturgis, EM; Wang, LE; Wei, Q; Xiong, P1
Cheng, L; Eicher, SA; Guo, Z; Hong, WK; Spitz, MR; Wei, Q1
Herzog, C; Hu, X; Singh, SV; Zimniak, P1
Nersesyan, AK1
Chang, P; Eicher, SA; Firozi, PF; Hong, WK; Li, D; Spitz, MR; Sturgis, EM; Wang, LE; Wei, Q; Xiong, P1
Chang, P; El-Naggar, AK; Li, D; Sturgis, EM; Wang, LE; Wei, Q1

Trials

1 trial(s) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Carcinoma, Squamous Cell

ArticleYear
In vitro benzo[a]pyrene diol epoxide-induced DNA adducts and risk of squamous cell carcinoma of head and neck.
    Cancer research, 2007, Jun-15, Volume: 67, Issue:12

    Topics: Aged; Alcohol Drinking; Benzopyrenes; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; DNA Adducts; Female; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Head and Neck Neoplasms; Humans; In Vitro Techniques; Male; Middle Aged; Risk Factors; Smoking

2007

Other Studies

14 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Carcinoma, Squamous Cell

ArticleYear
Mutagen sensitivity and DNA repair of the EGFR gene in oropharyngeal cancer.
    Oral oncology, 2010, Volume: 46, Issue:7

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Carcinoma, Squamous Cell; Comet Assay; DNA Damage; DNA Repair; Female; Genes, erbB-1; Humans; Immunohistochemistry; Male; Middle Aged; Mutagens; Oropharyngeal Neoplasms

2010
The impact of EGFR stimulation and inhibition on BPDE induced DNA fragmentation in oral/oropharyngeal mucosa in vitro.
    Oral oncology, 2011, Volume: 47, Issue:12

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Case-Control Studies; Cetuximab; Cisplatin; DNA Damage; Down-Regulation; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Male; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Oropharyngeal Neoplasms; Protein Kinase Inhibitors; Quinazolines; Tumor Necrosis Factor-alpha; Up-Regulation; Young Adult

2011
BPDE-induced lymphocytic 3p21.3 aberrations may predict head and neck carcinoma risk.
    Cancer, 2002, Aug-01, Volume: 95, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aged; Carcinogens; Carcinoma, Squamous Cell; Chromosome Aberrations; Chromosomes, Human, Pair 3; Female; Genetic Predisposition to Disease; Genetic Testing; Head and Neck Neoplasms; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Middle Aged; Predictive Value of Tests

2002
Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:12

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Automation; Carcinoma, Squamous Cell; China; Culture Media; Culture Techniques; Diagnostic Imaging; DNA Adducts; Esophageal Neoplasms; Esophagectomy; Humans; Immunohistochemistry; Keratinocytes; Polycyclic Aromatic Hydrocarbons; Rabbits; Reference Values; Reproducibility of Results; Sampling Studies; Sensitivity and Specificity

2002
The carcinogen (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene induces Cdc25B expression in human bronchial and lung cancer cells.
    Cancer research, 2003, Feb-15, Volume: 63, Issue:4

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma, Bronchiolo-Alveolar; Bronchi; Carcinogens; Carcinoma, Squamous Cell; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Epithelial Cells; Gene Expression; Humans; Lung Neoplasms; RNA, Messenger; Tumor Cells, Cultured

2003
[Study on lung carcinogenesis associated genes in human lung squamous cell carcinoma and malignant transformation of human bronchial epithelial cells induced by carcinogen].
    Zhonghua yi xue za zhi, 2003, Dec-25, Volume: 83, Issue:24

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bronchi; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Lung Neoplasms; Nickel; Oligonucleotide Array Sequence Analysis

2003
High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma.
    Cancer letters, 2004, Apr-30, Volume: 207, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Bronchi; Carcinogens; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Deoxyguanosine; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Epithelial Cells; Female; Humans; Lung Neoplasms; Male; Middle Aged

2004
Characterization of 67 kD laminin receptor, a protein whose gene is overexpressed on treatment of cells with anti-benzo[a]pyrene-7,8-diol-9,10-epoxide.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 90, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Base Sequence; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Molecular Sequence Data; Receptors, Laminin; RNA; Sequence Analysis, RNA; Transfection

2006
Ataxia-telangiectasia mutated expression is associated with tobacco smoke exposure in esophageal cancer tissues and benzo[a]pyrene diol epoxide in cell lines.
    International journal of cancer, 2007, Jan-01, Volume: 120, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Ataxia Telangiectasia Mutated Proteins; Biomarkers, Tumor; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Cell Cycle Proteins; DNA-Binding Proteins; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Precancerous Conditions; Protein Serine-Threonine Kinases; RNA, Messenger; Smoking; Tumor Cells, Cultured; Tumor Suppressor Proteins

2007
In vitro benzo[a]pyrene diol epoxide-induced DNA damage and chromosomal aberrations in primary lymphocytes, smoking, and risk of squamous cell carcinoma of the head and neck.
    International journal of cancer, 2007, Dec-15, Volume: 121, Issue:12

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Chromosome Aberrations; Comet Assay; DNA Damage; DNA Repair; Female; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Lymphocytes; Male; Middle Aged; Mutagens; Odds Ratio; Risk Assessment; Risk Factors; Smoking; Texas

2007
Reduced DNA repair capacity in head and neck cancer patients.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; DNA Repair; Dose-Response Relationship, Drug; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Odds Ratio; Pilot Projects; Risk Factors; Smoking

1998
Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase.
    Cancer research, 1999, May-15, Volume: 59, Issue:10

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Air Pollutants; Alleles; Amino Acid Substitution; Carcinogens, Environmental; Carcinoma, Squamous Cell; DNA Adducts; DNA Damage; Genetic Predisposition to Disease; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Laryngeal Neoplasms; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured

1999
Re: Benzo[a]pyrene diol epoxide and bleomycin sensitivity and susceptibility to cancer of upper aerodigestive tract.
    Journal of the National Cancer Institute, 1999, Aug-04, Volume: 91, Issue:15

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bleomycin; Carcinogens; Carcinoma, Squamous Cell; Chromosomes; DNA Damage; Head and Neck Neoplasms; Heterozygote; Homozygote; Humans; Lymphocytes; Mutagens

1999
In vitro BPDE-induced DNA adducts in peripheral lymphocytes as a risk factor for squamous cell carcinoma of the head and neck.
    International journal of cancer, 2001, Aug-01, Volume: 93, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Case-Control Studies; Cells, Cultured; Disease Susceptibility; DNA Adducts; DNA Repair; DNA, Neoplasm; Female; Head and Neck Neoplasms; Humans; Lymphocytes; Male; Middle Aged; Risk Factors; Smoking

2001