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7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Breast Cancer

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with Breast Cancer in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's11 (84.62)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faraglia, B; Motykiewicz, G; Santella, RM; Senie, RT; Terry, MB; Wang, LW1
Bondy, ML; Brewster, A; Shi, Q; Singletary, SE; Wang, LE; Wei, Q1
Berwick, M; Vineis, P1
Agrawal, M; Kennedy, DO; Motykiewicz, G; Santella, RM; Senie, RT; Shen, J; Terry, MB; Zhang, FF1
Burchiel, SW; Burdick, AD; Ivnitski-Steele, ID; Lauer, FT1
Gallagher, EP; Magee, P; Peters, WH; Pool-Zobel, BL; Rowland, I; Steiner, C1
Botlagunta, M; Chen, JH; Farabaugh, P; Lisok, A; Mironchik, Y; Mukadam, S; Patel, AH; Raman, A; Raman, V; Van Diest, P; Vesuna, F; Winnard, P1
Bowden, GT; Gudas, JM; Jeffy, BD; Romagnolo, D; Schultz, EU; Selmin, O1
Dipple, A; Khan, QA1
Bondy, ML; Li, D; Shen, H; Singletary, SE; Spitz, MR; Wang, LE; Wei, Q; Xiong, P1
Chen, EJ; Chirnomas, RB; Gudas, JM; Jeffy, BD; Romagnolo, DF1
Chirnomas, RB; Jeffy, BD; Romagnolo, DF1
Baird, WM; Merrick, BA; Nikbakht, A; Pruess-Schwartz, D; Selkirk, JK1

Other Studies

13 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Breast Cancer

ArticleYear
Removal of benzo(a)pyrene diol epoxide (BPDE)-DNA adducts as a measure of DNA repair capacity in lymphoblastoid cell lines from sisters discordant for breast cancer.
    Environmental and molecular mutagenesis, 2002, Volume: 40, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Age of Onset; Breast Neoplasms; Cell Line; Culture Media, Serum-Free; DNA Adducts; DNA Repair; Female; Humans; Lymphocytes; Middle Aged; Mutagens; Nuclear Family

2002
Reduced DNA repair of benzo[a]pyrene diol epoxide-induced adducts and common XPD polymorphisms in breast cancer patients.
    Carcinogenesis, 2004, Volume: 25, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Breast Neoplasms; Carcinogens; Case-Control Studies; DNA Adducts; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Genotype; Humans; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proteins; Risk Factors; Transcription Factors; Xeroderma Pigmentosum Group D Protein

2004
Measuring DNA repair capacity: small steps.
    Journal of the National Cancer Institute, 2005, Jan-19, Volume: 97, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Body Weight; Breast Neoplasms; Carcinogens; Confounding Factors, Epidemiologic; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Female; Genes, BRCA1; Genes, BRCA2; Humans; Obesity; Research Design

2005
DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer.
    Journal of the National Cancer Institute, 2005, Jan-19, Volume: 97, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Analysis of Variance; Breast Neoplasms; Carcinogens; Case-Control Studies; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Female; Fluorescent Antibody Technique, Direct; Genetic Predisposition to Disease; Humans; Logistic Models; Lymphocytes; Mutagens; Odds Ratio; Siblings

2005
PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells.
    Carcinogenesis, 2006, Volume: 27, Issue:11

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Apoptosis; Breast Neoplasms; Calcium; Carcinogens; Cell Line, Tumor; Focal Adhesion Kinase 2; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

2006
Genistein protects human mammary epithelial cells from benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide and 4-hydroxy-2-nonenal genotoxicity by modulating the glutathione/glutathione S-transferase system.
    Carcinogenesis, 2007, Volume: 28, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aldehydes; Anticarcinogenic Agents; Breast; Breast Neoplasms; Carcinogens; Cell Line; Cell Line, Tumor; DNA Primers; Epithelial Cells; Female; Genistein; Glutathione S-Transferase pi; Glutathione Transferase; Humans; RNA, Messenger

2007
Oncogenic role of DDX3 in breast cancer biogenesis.
    Oncogene, 2008, Jun-26, Volume: 27, Issue:28

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Breast Neoplasms; Cadherins; Carcinogens; Cell Line, Tumor; Cell Movement; DEAD-box RNA Helicases; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Neoplasm Metastasis; Phenotype; Promoter Regions, Genetic; Smoking; Wound Healing

2008
Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide.
    Molecular carcinogenesis, 1999, Volume: 26, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Blotting, Western; Breast Neoplasms; Carcinogens; Dose-Response Relationship, Drug; Down-Regulation; Exons; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Ovarian Neoplasms; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Ribosomal; Time Factors; Tumor Cells, Cultured; Up-Regulation

1999
Diverse chemical carcinogens fail to induce G(1) arrest in MCF-7 cells.
    Carcinogenesis, 2000, Volume: 21, Issue:8

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetoxyacetylaminofluorene; Alkylating Agents; Breast Neoplasms; Carcinogens; Cell Cycle; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; G1 Phase; Humans; Methylnitronitrosoguanidine; Nocodazole; Stereoisomerism; Tumor Cells, Cultured

2000
Sensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study.
    Cancer research, 2001, Dec-01, Volume: 61, Issue:23

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Breast Neoplasms; Carcinogens; Case-Control Studies; Chromosome Aberrations; Cocarcinogenesis; Female; Genetic Predisposition to Disease; Glutathione Transferase; Humans; Middle Aged; Pilot Projects; Polymorphism, Genetic

2001
Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
    Cancer research, 2002, Jan-01, Volume: 62, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Biotransformation; BRCA1 Protein; Breast Neoplasms; Carcinogens; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors.
    Environmental and molecular mutagenesis, 2002, Volume: 39, Issue:2-3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzoflavones; Blotting, Western; BRCA1 Protein; Breast Neoplasms; Carcinogens; DNA Damage; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
Benzo(a)pyrene:DNA adduct formation in normal human mammary epithelial cell cultures and the human mammary carcinoma T47D cell line.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzopyrenes; Breast; Breast Neoplasms; Carcinoma; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA, Neoplasm; Epithelium; Female; Humans; Hydrolysis; Tritium

1986