68ga-dotanoc and Parotid-Neoplasms

A patient with moderately differentiated pancreatic neuroendocrine tumor with synchronous multifocal liver metastases was referred for further staging with PET/CT. The examinations were performed on 2 consecutive days and showed mild 68Ga-DOTANOC and intense 18F-FDG uptake in an incidental right parotid nodule. Differential diagnoses include primary or metastatic neuroendocrine tumor, malignant or benign primary parotid tumor, and intraparotid lymph node. Histology revealed characteristics of a Warthin tumor. While focal FDG uptake in Warthin tumor is frequently described, the somatostatin expression was rarely reported. This clinical case describes 68Ga-DOTANOC and 18F-FDG uptake in a parotid Warthin tumor histologically confirmed.

Topics: Adenolymphoma; Biological Transport; Female; Fluorodeoxyglucose F18; Humans; Incidental Findings; Male; Middle Aged; Organometallic Compounds; Parotid Neoplasms; Positron Emission Tomography Computed Tomography

Tumor-induced osteomalacia is a rare paraneoplastic syndrome, usually caused by small benign mesenchymal tumors. The tumors most arise within the extremities, whereas occurrence within the parotid gland is quite rare. A 54-year-old woman who presented with bone pain and muscle weakness for 2 years was clinically suspected of having tumor-induced osteomalacia. A Ga-DOTANOC PET/CT was performed for localization of the causative tumor. The images demonstrated intense radiotracer accumulation in a soft tissue nodule in deep lobe of the right parotid gland. Subsequent surgical resection and pathologic analysis confirmed the diagnosis of parotid basal cell adenoma.

Topics: Adenoma; Female; Humans; Middle Aged; Neoplasms, Connective Tissue; Organometallic Compounds; Osteomalacia; Paraneoplastic Syndromes; Parotid Neoplasms; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals