68ga-dotanoc and Adrenocortical-Carcinoma

Multiple endocrine neoplasia 1 (MEN1) syndrome is an autosomal dominant syndrome comprising a triad of pancreatic, pituitary, and parathyroid tumors. Adrenal cortical carcinoma occurs rarely in MEN1 syndrome. Here, we have presented a case of a 62-year-old woman with adrenal mass and elevated serum parathormone levels, who underwent 68Ga-DOTANOC PET/CT. 68Ga-DOTANOC PET/CT showed intense tracer concentration in the left adrenal mass and lesions in the liver, pancreas, and peritoneum. Biopsy of the peritoneal deposit revealed metastatic adrenocortical carcinoma, and further genetic testing showed MEN1 mutation.

Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Female; Humans; Middle Aged; Multiple Endocrine Neoplasia; Multiple Endocrine Neoplasia Type 1; Organometallic Compounds; Positron Emission Tomography Computed Tomography