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6-phenylhexyl isothiocyanate and Multiple Myeloma

6-phenylhexyl isothiocyanate has been researched along with Multiple Myeloma in 3 studies

*Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. [MeSH]

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiao, JW; Feng, J; Gallagher, R; Lee, MY; Lin, X; Liu, D; Lu, Q; Zhao, X1
Hong, XL; Lu, QY; Zhang, ZC; Zhao, JN1
Liu, DL; Lu, QY; Wang, Z1

Other Studies

3 other study(ies) available for 6-phenylhexyl isothiocyanate and Multiple Myeloma

ArticleYear
Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways.
    Journal of hematology & oncology, 2008, Jun-09, Volume: 1

    Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Histone Deacetylase Inhibitors; Histones; Humans; Isothiocyanates; Membrane Potential, Mitochondrial; Multiple Myeloma; ras Proteins; Receptors, Interleukin-6; Vascular Endothelial Growth Factor A

2008
[Inhibitory effect of phenylhexyl isothiocyanate on notch signaling of multiple myeloma cells in vitro].
    Zhongguo shi yan xue ye xue za zhi, 2011, Volume: 19, Issue:4

    Topics: Cell Line, Tumor; Humans; Intercellular Signaling Peptides and Proteins; Isothiocyanates; Jagged-2 Protein; Membrane Proteins; Multiple Myeloma; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptor, Notch1; Signal Transduction

2011
[Effect of phenylhexyl isothiocyanate on inducing apoptosis of multiple myeloma cells in vitro].
    Zhongguo shi yan xue ye xue za zhi, 2008, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; Isothiocyanates; Multiple Myeloma; Vascular Endothelial Growth Factor A

2008