6-methylthiopurine has been researched along with Liver Cirrhosis in 1 studies
6-methylthiopurine : A thiopurine that is 9H-purine substituted by a methylsulfanyl group at position 6.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine is a key drug in the management of autoimmune hepatitis (AIH), with effects mediated via conversion to 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-MMP), the latter controlled by thiopurine methyltransferase (TPMT)." | 1.33 | Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis. ( Allan, ML; Bornstein, JD; Heneghan, MA; Muir, AJ; Tendler, DA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heneghan, MA | 1 |
| Allan, ML | 1 |
| Bornstein, JD | 1 |
| Muir, AJ | 1 |
| Tendler, DA | 1 |
1 other study available for 6-methylthiopurine and Liver Cirrhosis
| Article | Year |
|---|---|
Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Drug Monitoring; Female; Genotype; | 2006 |