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6-methylthiopurine and Liver Cirrhosis

6-methylthiopurine has been researched along with Liver Cirrhosis in 1 studies

6-methylthiopurine : A thiopurine that is 9H-purine substituted by a methylsulfanyl group at position 6.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Azathioprine is a key drug in the management of autoimmune hepatitis (AIH), with effects mediated via conversion to 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-MMP), the latter controlled by thiopurine methyltransferase (TPMT)."1.33Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis. ( Allan, ML; Bornstein, JD; Heneghan, MA; Muir, AJ; Tendler, DA, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heneghan, MA1
Allan, ML1
Bornstein, JD1
Muir, AJ1
Tendler, DA1

Other Studies

1 other study available for 6-methylthiopurine and Liver Cirrhosis

ArticleYear
Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis.
    Journal of hepatology, 2006, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Drug Monitoring; Female; Genotype;

2006