6-methyltetrahydropterin has been researched along with Substance-Withdrawal-Syndrome* in 1 studies
1 other study(ies) available for 6-methyltetrahydropterin and Substance-Withdrawal-Syndrome
| Article | Year |
|---|---|
Study of tetrahydrobiopterin and 6-methyltetrahydropterin on alcohol dependence in mice.
The literature establishes a potential link between the function of tetrahydroisoquinolines in the biological actions of alcohol and the reduced pterin cofactor needed for synthesis of certain neurotransmitters. The effect of the administration of 6-methyltetrahydropterin and tetrahydrobiopterin upon alcohol withdrawal in mice was tested. Dependence was produced by ip administration of alcohol, supplemented by alcohol delivered by a subcutaneously implanted silastic tube. Administration of the reduced pterins at relatively high doses did not reduce the magnitude of the alcohol withdrawal syndrome. Topics: Alcoholism; Animals; Biopterins; Ethanol; Female; Humans; Mice; Pteridines; Pterins; Substance Withdrawal Syndrome | 1983 |