6-methylsulfinylhexyl-isothiocyanate and Cognition-Disorders

6-methylsulfinylhexyl-isothiocyanate has been researched along with Cognition-Disorders* in 1 studies

Other Studies

1 other study(ies) available for 6-methylsulfinylhexyl-isothiocyanate and Cognition-Disorders

ArticleYear
Protective Effects of 6-(Methylsulfinyl)hexyl Isothiocyanate on Aβ
    International journal of molecular sciences, 2018, Jul-18, Volume: 19, Issue:7

    Alzheimer's disease (AD) is the most common form of dementia among older people. Although soluble amyloid species are recognized triggers of the disease, no therapeutic approach is able to stop it. 6-(Methylsulfinyl)hexyl isothiocyanate (6-MSITC) is a major bioactive compound in Wasabia japonica, which is a typical Japanese pungent spice. Recently, in vivo and in vitro studies demonstrated that 6-MSITC has several biological properties. The aim of the present study was to investigate the neuroprotective activity of 6-MSITC in a murine AD model, induced by intracerebroventricular injection of β-amyloid oligomers (Aβ

    Topics: Amyloid beta-Peptides; Animals; Apoptosis; Caspases; Cell Death; Cognition Disorders; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinase 3 beta; Hippocampus; Inflammation; Isothiocyanates; Mice; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Phosphorylation

2018