Compounds > 6-ketoprostaglandin-f1-alpha

6-ketoprostaglandin-f1-alpha and Pituitary-Neoplasms

6-ketoprostaglandin-f1-alpha has been researched along with Pituitary-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 6-ketoprostaglandin-f1-alpha and Pituitary-Neoplasms

Article	Year
Effect of indomethacin treatment on prostaglandin excretion and tissue phospholipid fatty acid composition in rats bearing mammotropic pituitary tumor, MtT-F4. Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3 The hypothesis that hormonal changes induced by the mammotropic pituitary tumor, MtT-F4, might accelerate the conversion of n-6 fatty acids to prostaglandins, resulting in a partial depletion of n-6 fatty acids was examined. In tumor-bearing rats, the administration of indomethacin induced a 50% reduction of the urinary prostaglandin levels, but exerted no significant effect on the fatty acid composition of the tissue phospholipids. It is concluded that the observed depletion of n-6 fatty acids in tumor-bearing rats is not caused by an increased production of prostaglandins. Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Fatty Acids; Indomethacin; Kidney; Liver; Male; Mammary Neoplasms, Experimental; Phospholipids; Pituitary Neoplasms; Prostaglandins; Rats; Rats, Inbred F344; Tissue Distribution	1986

Article

Year

Effect of indomethacin treatment on prostaglandin excretion and tissue phospholipid fatty acid composition in rats bearing mammotropic pituitary tumor, MtT-F4.

Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3

The hypothesis that hormonal changes induced by the mammotropic pituitary tumor, MtT-F4, might accelerate the conversion of n-6 fatty acids to prostaglandins, resulting in a partial depletion of n-6 fatty acids was examined. In tumor-bearing rats, the administration of indomethacin induced a 50% reduction of the urinary prostaglandin levels, but exerted no significant effect on the fatty acid composition of the tissue phospholipids. It is concluded that the observed depletion of n-6 fatty acids in tumor-bearing rats is not caused by an increased production of prostaglandins.

Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Fatty Acids; Indomethacin; Kidney; Liver; Male; Mammary Neoplasms, Experimental; Phospholipids; Pituitary Neoplasms; Prostaglandins; Rats; Rats, Inbred F344; Tissue Distribution

1986