6-ketoprostaglandin-f1-alpha has been researched along with Dentigerous-Cyst* in 2 studies
2 other study(ies) available for 6-ketoprostaglandin-f1-alpha and Dentigerous-Cyst
| Article | Year |
|---|---|
Enhancement of human dental cyst PGI2 formation by platelet derived growth factor and its role in cyst growth and bone resorption.
Various prostaglandins, particularly PGE2 and PGI2, appear to play a major role in osteolytic processes. Radiochromatographic studies have demonstrated that 6-oxo-PGF1-alpha is a major product of exogenously added arachidonic acid in human dental cysts. As platelets may also act as inflammatory cells, platelet-derived growth factor might also have a PGI2-stimulating influence in such cysts. Eleven human dental cysts were examined by a radioimmunoassay and bioassay which can show PGI2 synthesis in human dental cysts without addition of PDGF. Incremental PDGF addition caused a highly significant increase in the rate of PGI2 synthesis. PGDF thus stimulates PGI2 synthesis in chronic inflammatory processes in vitro and may thereby elicit or accelerate osteolysis. Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Bone Resorption; Dentigerous Cyst; Epoprostenol; Female; Humans; Male; Middle Aged; Platelet-Derived Growth Factor; Radioimmunoassay | 1989 |
Prostaglandin synthesis in dental cysts.
The synthesis of prostaglandins by dental squamous cell cysts was studied. Radiothinlayer-chromatography (RTLC) showed C14-labelled arachidonic acid to be converted into the prostaglandins PGE2, 6-oxo-PGF1 alpha, PGF2 alpha and PDG2. In addition, hydroxyfatty acid synthesis in excess of total prostaglandin production was observed. The substances mentioned are thought to be causally involved in the osteolytic activity of dental cysts. Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Dentigerous Cyst; Dinoprost; Dinoprostone; Female; Humans; Jaw Diseases; Male; Middle Aged; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F | 1985 |