6-hydroxynorketamine has been researched along with Disease Models, Animal in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Ju, L; Liu, P; Yang, J; Zhu, T | 1 |
| Herzog, DP; Lutz, B; Mellema, RM; Müller, MB; Remmers, F; Treccani, G | 1 |
| Aleksandrova, LR; Phillips, AG; Wang, YT | 1 |
| Jokinen, V; Kalso, EA; Lilius, TO; Niemi, M; Rauhala, PV; Viisanen, H | 1 |
| Chen, GD; Chou, D; Ho, YC; Hsieh, MC; Lai, CY; Lee, AS; Lin, TB; Peng, HY; Wang, HH; Wen, YC; Yang, PS | 1 |
| Chang, L; Chen, J; Fujita, Y; Hashimoto, K; Ma, M; Pu, Y; Xiong, Z; Zhang, K | 1 |
| Abe, M; Chaki, S; Hashimoto, K; Nozawa, D; Qu, Y; Yang, C | 1 |
7 other study(ies) available for 6-hydroxynorketamine and Disease Models, Animal
| Article | Year |
|---|---|
BDNF-TrkB signaling-mediated upregulation of Narp is involved in the antidepressant-like effects of (2R,6R)-hydroxynorketamine in a chronic restraint stress mouse model.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Depression; Disease Models, Animal; Female; Ketamine; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Receptor, trkB; Up-Regulation | 2022 |
Sexually Dimorphic Behavioral Profile in a Transgenic Model Enabling Targeted Recombination in Active Neurons in Response to Ketamine and (2R,6R)-Hydroxynorketamine Administration.
Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Nucleus; Disease Models, Animal; Female; Green Fluorescent Proteins; Hippocampus; Ketamine; Male; Memory, Episodic; Mice, Transgenic; Neurons; Recombination, Genetic; Sex Characteristics; Social Behavior | 2020 |
Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression.
Topics: Animals; Depression; Disease Models, Animal; Hippocampus; Immobilization; Ketamine; Long-Term Potentiation; Male; Motor Activity; Open Field Test; Rats, Inbred WKY; Spatial Memory; Stress, Psychological; Swimming; Synaptic Transmission | 2020 |
Interactions of (2S,6S;2R,6R)-Hydroxynorketamine, a Secondary Metabolite of (R,S)-Ketamine, with Morphine.
Topics: Analgesics, Opioid; Anesthetics, Dissociative; Animals; Behavior, Animal; Brain; Disease Models, Animal; Drug Interactions; Drug Tolerance; Ketamine; Male; Morphine; Motor Activity; Nociception; Nociceptive Pain; Pain Threshold; Rats, Sprague-Dawley | 2018 |
(2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
Topics: Animals; Antidepressive Agents; Cell Membrane; Cytosol; Depressive Disorder; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Helplessness, Learned; Ketamine; Male; Miniature Postsynaptic Potentials; Neurons; Periaqueductal Gray; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Synapses; Tissue Culture Techniques | 2018 |
Beneficial effects of (R)-ketamine, but not its metabolite (2R,6R)-hydroxynorketamine, in the depression-like phenotype, inflammatory bone markers, and bone mineral density in a chronic social defeat stress model.
Topics: Animals; Antidepressive Agents; Biomarkers; Bone Density; Depression; Depressive Disorder; Disease Models, Animal; Inflammation; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Osteopontin; Osteoprotegerin; RANK Ligand; Stress, Psychological | 2019 |
(R)-Ketamine Shows Greater Potency and Longer Lasting Antidepressant Effects Than Its Metabolite (2R,6R)-Hydroxynorketamine.
Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dominance-Subordination; Inflammation; Ketamine; Lipopolysaccharides; Male; Mice, Inbred C57BL; Stereoisomerism; Stress, Psychological; Time Factors | 2017 |