Page last updated: 2024-09-04

6-hydroxynorketamine and Depression, Involutional

6-hydroxynorketamine has been researched along with Depression, Involutional in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Browne, CA; Lucki, I; Wulf, HA; Zarate, CA1
Burke, AK; Choo, TH; Cooper, TB; Galfalvy, HC; Grunebaum, MF; Mann, JJ; Parris, MS; Suckow, RF1
Elmer, GI; Gould, TD; Mayo, CL; Tapocik, JD; Zanos, P1
Aguilar-Valles, A; Bermudez, S; De Gregorio, D; Eslamizade, MJ; Gobbi, G; Khlaifia, A; Lacaille, JC; Lopez-Canul, M; Matta-Camacho, E; Rurak, GM; Salmaso, N; Simard, S; Skaleka, A; Sonenberg, N; Torres-Berrio, A1

Trials

1 trial(s) available for 6-hydroxynorketamine and Depression, Involutional

ArticleYear
Ketamine metabolite pilot study in a suicidal depression trial.
    Journal of psychiatric research, 2019, Volume: 117

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Humans; Infusions, Parenteral; Ketamine; Midazolam; Outcome Assessment, Health Care; Pilot Projects; Severity of Illness Index; Suicidal Ideation

2019

Other Studies

3 other study(ies) available for 6-hydroxynorketamine and Depression, Involutional

ArticleYear
Mediation of the behavioral effects of ketamine and (2R,6R)-hydroxynorketamine in mice by kappa opioid receptors.
    Psychopharmacology, 2022, Volume: 239, Issue:7

    Topics: Animals; Behavior, Animal; Depressive Disorder, Major; Humans; Ketamine; Mice; Naltrexone; Receptors, Opioid, kappa

2022
Ketamine metabolite (2R,6R)-hydroxynorketamine reverses behavioral despair produced by adolescent trauma.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 196

    Topics: Animals; Behavior, Animal; Depressive Disorder, Major; Female; Ketamine; Male; Mice; Mice, Inbred C57BL; Predatory Behavior; Stress, Psychological

2020
Antidepressant actions of ketamine engage cell-specific translation via eIF4E.
    Nature, 2021, Volume: 590, Issue:7845

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antidepressive Agents; Cell Cycle Proteins; Depressive Disorder, Major; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factors; Excitatory Postsynaptic Potentials; Hippocampus; Inhibitory Postsynaptic Potentials; Interneurons; Ketamine; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mutation; Neural Inhibition; Neurons; Protein Biosynthesis; Pyramidal Cells; Synaptic Transmission

2021