Page last updated: 2024-09-04

6-hydroxynorketamine and Depression, Endogenous

6-hydroxynorketamine has been researched along with Depression, Endogenous in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaki, S; Hashimoto, K; Koike, H; Mizuno-Yasuhira, A; Qu, Y; Toki, H; Yamaguchi, JI; Yang, C1
Chen, GD; Chou, D; Ho, YC; Hsieh, MC; Lai, CY; Lee, AS; Lin, TB; Peng, HY; Wang, HH; Wen, YC; Yang, PS1
Chang, L; Chen, J; Fujita, Y; Hashimoto, K; Ma, M; Pu, Y; Xiong, Z; Zhang, K1
Abe, M; Chaki, S; Hashimoto, K; Nozawa, D; Qu, Y; Yang, C1

Other Studies

4 other study(ies) available for 6-hydroxynorketamine and Depression, Endogenous

ArticleYear
(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:9

    Topics: Animals; Antidepressive Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Depressive Disorder; Inflammation; Ketamine; Lipopolysaccharides; Male; Mice, Inbred C57BL; Mice, Inbred ICR

2018
(2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
    Neuropharmacology, 2018, 09-01, Volume: 139

    Topics: Animals; Antidepressive Agents; Cell Membrane; Cytosol; Depressive Disorder; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Helplessness, Learned; Ketamine; Male; Miniature Postsynaptic Potentials; Neurons; Periaqueductal Gray; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Synapses; Tissue Culture Techniques

2018
Beneficial effects of (R)-ketamine, but not its metabolite (2R,6R)-hydroxynorketamine, in the depression-like phenotype, inflammatory bone markers, and bone mineral density in a chronic social defeat stress model.
    Behavioural brain research, 2019, 08-05, Volume: 368

    Topics: Animals; Antidepressive Agents; Biomarkers; Bone Density; Depression; Depressive Disorder; Disease Models, Animal; Inflammation; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Osteopontin; Osteoprotegerin; RANK Ligand; Stress, Psychological

2019
(R)-Ketamine Shows Greater Potency and Longer Lasting Antidepressant Effects Than Its Metabolite (2R,6R)-Hydroxynorketamine.
    Biological psychiatry, 2017, 09-01, Volume: 82, Issue:5

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dominance-Subordination; Inflammation; Ketamine; Lipopolysaccharides; Male; Mice, Inbred C57BL; Stereoisomerism; Stress, Psychological; Time Factors

2017