6-hydroxymelatonin has been researched along with Depressive Disorder in 7 studies
6-hydroxymelatonin : A member of the class of tryptamines that is melatonin with a hydroxy group substituent at position 6.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levels of the melatonin metabolite, 6-hydroxymelatonin sulfate, were measured in overnight urine from 31 prepubertal children with major depressive disorder and 15 normal control children with very low family loading for affective disorder." | 7.68 | Nocturnal urinary excretion of 6-hydroxymelatonin sulfate in prepubertal major depressive disorder. ( Birmaher, B; Dahl, RE; Perel, JM; Puig-Antich, J; Ryan, ND; Thomas, CR; Waterman, GS; Williamson, DE, 1992) |
| "Levels of the melatonin metabolite, 6-hydroxymelatonin sulfate, were measured in overnight urine from 31 prepubertal children with major depressive disorder and 15 normal control children with very low family loading for affective disorder." | 3.68 | Nocturnal urinary excretion of 6-hydroxymelatonin sulfate in prepubertal major depressive disorder. ( Birmaher, B; Dahl, RE; Perel, JM; Puig-Antich, J; Ryan, ND; Thomas, CR; Waterman, GS; Williamson, DE, 1992) |
| " There was no change in alpha MT6s excretion, and thus the previously reported potentiation of the efficacy of tricyclic antidepressants in combination with T3 does not appear to be mediated through an alteration in noradrenergic neurotransmission." | 1.28 | A study of the effects of desipramine treatment alone and in combination with L-triiodothyronine on 6-sulphatoxymelatonin excretion in depressed patients. ( Arendt, J; Bearn, J; Checkley, SA; Franey, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Waterman, GS | 1 |
| Ryan, ND | 1 |
| Perel, JM | 1 |
| Dahl, RE | 1 |
| Birmaher, B | 1 |
| Williamson, DE | 1 |
| Thomas, CR | 1 |
| Puig-Antich, J | 1 |
| Bearn, J | 1 |
| Franey, C | 1 |
| Arendt, J | 2 |
| Checkley, SA | 1 |
| Golden, RN | 2 |
| Potter, WZ | 2 |
| Sack, RL | 1 |
| Lewy, AJ | 1 |
| Markey, SP | 1 |
| Risby, ED | 1 |
| Rudorfer, MV | 1 |
| Cowdry, RW | 1 |
| Rosenthal, NE | 1 |
| Jacobsen, FM | 1 |
| Sack, DA | 1 |
| James, SP | 1 |
| Parry, BL | 1 |
| Wehr, TA | 1 |
| Boyce, PM | 1 |
2 trials available for 6-hydroxymelatonin and Depressive Disorder
| Article | Year |
|---|---|
Antidepressants reduce whole-body norepinephrine turnover while enhancing 6-hydroxymelatonin output.
Topics: Adult; Animals; Antidepressive Agents; Bupropion; Depressive Disorder; Desipramine; Female; Humans; | 1988 |
Atenolol in seasonal affective disorder: a test of the melatonin hypothesis.
Topics: Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male | 1988 |
5 other studies available for 6-hydroxymelatonin and Depressive Disorder
| Article | Year |
|---|---|
Nocturnal urinary excretion of 6-hydroxymelatonin sulfate in prepubertal major depressive disorder.
Topics: Adolescent; Child; Circadian Rhythm; Depressive Disorder; Female; Humans; Male; Melatonin; Personali | 1992 |
A study of the effects of desipramine treatment alone and in combination with L-triiodothyronine on 6-sulphatoxymelatonin excretion in depressed patients.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Mela | 1989 |
Neurochemical and neuroendocrine dysregulation in affective disorders.
Topics: Acetylcholine; Anxiety Disorders; Arousal; Brain; Depressive Disorder; Hormones; Humans; Melatonin; | 1986 |
Desmethylimipramine treatment increases melatonin production in humans.
Topics: Adult; Animals; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Middle Aged; Pine | 1986 |
6-Sulphatoxy melatonin in melancholia.
Topics: Adult; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Male; Melatonin; Middle A | 1985 |