6-hydroxychlorzoxazone has been researched along with Disorders of Excessive Somnolence in 1 studies
6-hydroxychlorzoxazone: chlorzoxazone metabolite in humans
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lasofoxifene was tested in 18 postmenopausal women with probe drugs for CYP2E1 and CYP2D6." | 2.72 | Effects of steady-state lasofoxifene on CYP2D6- and CYP2E1-mediated metabolism. ( Fisher, JM; Gardner, MJ; Kolluri, S; Moller, RA; Obach, RS; Taylor, AE; Walsky, RL, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moller, RA | 1 |
| Fisher, JM | 1 |
| Taylor, AE | 1 |
| Kolluri, S | 1 |
| Gardner, MJ | 1 |
| Obach, RS | 1 |
| Walsky, RL | 1 |
1 trial available for 6-hydroxychlorzoxazone and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Effects of steady-state lasofoxifene on CYP2D6- and CYP2E1-mediated metabolism.
Topics: Administration, Oral; Chlorzoxazone; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cy | 2006 |