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6-hydroxychlorzoxazone and Cystic Fibrosis of Pancreas

6-hydroxychlorzoxazone has been researched along with Cystic Fibrosis of Pancreas in 1 studies

6-hydroxychlorzoxazone: chlorzoxazone metabolite in humans

Research Excerpts

ExcerptRelevanceReference
" In our pursuit to identify potent modulators of Cl(-) secretion that may be useful to overcome the Cl(-) secretory defect in cystic fibrosis (CF), we have identified chlorzoxazone [5-chloro-2(3H)-benzoxazolone], a clinically used centrally acting muscle relaxant, as a stimulator of Cl(-) secretion in several epithelial cell types, including T84, Calu-3, and human bronchial epithelium."3.70Stimulation of Cl(-) secretion by chlorzoxazone. ( Bridges, RJ; Devor, DC; Gerlach, AC; Gondor, M; Pilewski, JM; Singh, AK, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singh, AK1
Devor, DC1
Gerlach, AC1
Gondor, M1
Pilewski, JM1
Bridges, RJ1

Other Studies

1 other study available for 6-hydroxychlorzoxazone and Cystic Fibrosis of Pancreas

ArticleYear
Stimulation of Cl(-) secretion by chlorzoxazone.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: Amiloride; Anions; Bronchi; Bumetanide; Cell Membrane; Cells, Cultured; Charybdotoxin; Chlorine; Chl

2000