6-hydroxychlorzoxazone has been researched along with Body Weight in 4 studies
6-hydroxychlorzoxazone: chlorzoxazone metabolite in humans
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further, the conventional chlorzoxazone method for in vivo phenotyping was studied by adjusting the dose to body weight in 10 healthy volunteers." | 5.12 | Phenotyping of cytochrome P450 2E1 in vitro and in vivo. ( Ernstgård, L; Johanson, G; Karlsson, AS; Warholm, M, 2007) |
| " The dose-response profile for renal CYP1A1 parallels that in the liver of either species but EROD-activities are 10-20 times lower than in the liver." | 1.32 | Different mechanisms of handling ingested polycyclic aromatic hydrocarbons in mammalian species: organ-specific response patterns of CYP1A1-induction after oral intake of PAH-contaminated soils. ( Hack, A; Roos, PH; Tschirbs, S; Welge, P; Wilhelm, M, 2004) |
| "Chlormethiazole inhibited the increase in the ethanol-induced CYP2E1 activity in vivo, as measured by chlorzoxazone 6-hydroxylation, but did not affect the level of CYP2E1 apoprotein." | 1.31 | Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole. ( Donohue, TM; Fang, C; French, BA; French, SW; Fu, P; Gouillon, Z; Hagbjork, AL; Ingelman-Sundberg, M; Li, J; Lucas, D, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, XP | 1 |
| Han, XM | 1 |
| Jiang, CH | 1 |
| Huang, SL | 1 |
| Liu, ZQ | 1 |
| Zhu, B | 1 |
| Zhou, G | 1 |
| Zhou, HH | 1 |
| Roos, PH | 1 |
| Tschirbs, S | 1 |
| Hack, A | 1 |
| Welge, P | 1 |
| Wilhelm, M | 1 |
| Ernstgård, L | 1 |
| Johanson, G | 1 |
| Karlsson, AS | 1 |
| Warholm, M | 1 |
| Gouillon, Z | 1 |
| Lucas, D | 1 |
| Li, J | 1 |
| Hagbjork, AL | 1 |
| French, BA | 1 |
| Fu, P | 1 |
| Fang, C | 1 |
| Ingelman-Sundberg, M | 1 |
| Donohue, TM | 1 |
| French, SW | 1 |
1 trial available for 6-hydroxychlorzoxazone and Body Weight
| Article | Year |
|---|---|
Phenotyping of cytochrome P450 2E1 in vitro and in vivo.
Topics: Adult; Body Weight; Chlorzoxazone; Cytochrome P-450 CYP2E1; Female; Humans; Male; Middle Aged | 2007 |
3 other studies available for 6-hydroxychlorzoxazone and Body Weight
| Article | Year |
|---|---|
Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population.
Topics: Adolescent; Adult; Body Mass Index; Body Weight; Chlorzoxazone; Cytochrome P-450 CYP2E1; Female; Hum | 2002 |
Different mechanisms of handling ingested polycyclic aromatic hydrocarbons in mammalian species: organ-specific response patterns of CYP1A1-induction after oral intake of PAH-contaminated soils.
Topics: Administration, Oral; Animals; Body Weight; Chlorzoxazone; Cytochrome P-450 CYP1A1; Dose-Response Re | 2004 |
Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole.
Topics: Animals; Apoenzymes; Body Weight; Chlormethiazole; Chlorzoxazone; Chymotrypsin; Cysteine Endopeptida | 2000 |