6-hydroxychlorzoxazone has been researched along with Alcoholism in 4 studies
6-hydroxychlorzoxazone: chlorzoxazone metabolite in humans
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lucas, D | 3 |
| Ménez, C | 2 |
| Girre, C | 3 |
| Bodénez, P | 1 |
| Hispard, E | 2 |
| Ménez, JF | 3 |
| Dally, S | 1 |
| Berthou, F | 1 |
| Poitrenaud, F | 1 |
| Nakanishi, S | 1 |
| Yamazaki, H | 1 |
1 review available for 6-hydroxychlorzoxazone and Alcoholism
| Article | Year |
|---|---|
[Induction of cytochrome P-450 IIE1 after chronic ethanol administration in man and in animals].
Topics: Alcoholism; Animals; Biomarkers; Chlorzoxazone; Cytochrome P-450 CYP2E1; Enzyme Induction; Ethanol; | 1997 |
3 other studies available for 6-hydroxychlorzoxazone and Alcoholism
| Article | Year |
|---|---|
Decrease in cytochrome P4502E1 as assessed by the rate of chlorzoxazone hydroxylation in alcoholics during the withdrawal phase.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P | 1995 |
Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics.
Topics: Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Chlorzoxazone; Cytochrome P-45 | 1994 |
High-performance liquid chromatographic determination of chlorzoxazone and 6-hydroxychlorzoxazone in serum: a tool for indirect evaluation of cytochrome P4502E1 activity in humans.
Topics: Administration, Oral; Adult; Alcoholism; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytoch | 1993 |