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6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Reperfusion Injury

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with Reperfusion Injury in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (33.33)18.2507
2000's8 (33.33)29.6817
2010's5 (20.83)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Arrault, A; Bouskela, E; Cordi, A; Dubuisson, M; Gharbi, S; Marchand, C; Marchand-Brynaert, J; Rees, JF; Rupin, A; Verbeuren, T1
Akkus, M; Aktas, A; Nergiz, Y; Ozmen, MF; Seker, U; Soker, S; Uyar, E1
Seker, U1
Bozkurt, M; Degirmentepe, RB1
Alizadeh, A; Amini, N; Babahajian, A; Entezari, M; Golab, F; Haramshahi, SMA; Katebi, M; Rasoolijazi, H; Sarveazad, A; Soleimani, M; Vahabzadeh, G1
Ikemura, K; Iwamoto, T; Kurata, T; Nakagawa, E; Okuda, M1
Arab, HA; Cheung, K; Hickman, PE; Kadkhodaee, M; Potter, JM; Roberts, MS; Walker, NI1
Batinic-Haberle, I; Derrick, M; Drobyshevsky, A; Du, H; Luo, K; Prasad, PV; Tan, S; Vasquez-Vivar, J; Yu, L1
Ikemura, K; Inoue, K; Iwamoto, T; Mizutani, H; Oka, H; Okuda, M1
Eum, HA; Lee, SH; Lee, SM1
Eum, HA; Lee, SM2
Aguilar-Nascimento, JE; Dias, CC; Marques, NR; Percário, S; Salomão, AB; Sano, V1
Kaundal, RK; Sharma, SS1
Lumlertgul, D; Thamprasert, K; Wongmekiat, O1
Clemens, JA; Panetta, JA1
Farhood, A; Fisher, MA; Jaeschke, H; Liu, P; McGuire, GM; Smith, CW1
Fung, KP; Nakamura, H; Wu, J; Wu, TW; Zeng, LH1
Baldwin, ST; Kirk, KA; Liu, YY; Nielsen, VG; Parks, DA; Skinner, K; Tan, S1
Abadie, C; Lecour, S; Maupoil, V; Rochette, L; Vergely, C; Walker, MK1
Ametani, MS; Haworth, RA; Southard, JH; Vreugdenhil, PK1
Baker, CJ; Barr, ML; Gade, PV; Longoria, J; Starnes, VA1
Alam, J; Das, DK; Ho, YS; Maulik, N; Yoshida, T1
Au, JX; Carey, D; Hashimoto, N; Mickle, DA; Wu, J; Wu, TW1

Reviews

1 review(s) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Reperfusion Injury

ArticleYear
Neuroprotection by antioxidants in models of global and focal ischemia.
    Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain Ischemia; Chromans; Corpus Striatum; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Rats; Rats, Wistar; Reperfusion Injury; Structure-Activity Relationship

1994

Other Studies

23 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Reperfusion Injury

ArticleYear
Protective effect of imidazolopyrazinone antioxidants on ischemia/reperfusion injury.
    Bioorganic & medicinal chemistry letters, 2003, Feb-24, Volume: 13, Issue:4

    Topics: Amidines; Animals; Antioxidants; Capillary Permeability; Cricetinae; Firefly Luciferin; Imidazoles; Lipid Peroxidation; Microcirculation; Protective Agents; Pyrazines; Reperfusion Injury; Structure-Activity Relationship

2003
Trolox is more successful than allopurinol to reduce degenerative effects of testicular ischemia/reperfusion injury in rats.
    Journal of pediatric urology, 2020, Volume: 16, Issue:4

    Topics: Allopurinol; Animals; Chromans; Humans; Ischemia; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spermatic Cord Torsion; Testis

2020
Response to letter to the editor 'Trolox is more successful than allopurinol to reduce degenerative effects of testicular ischemia/reperfusion injury in rats'.
    Journal of pediatric urology, 2020, Volume: 16, Issue:6

    Topics: Allopurinol; Animals; Chromans; Ischemia; Male; Rats; Reperfusion Injury; Testis

2020
Letter to the editor: Trolox is more successful than allopurinol to reduce degenerative effects of testicular ischemia/reperfusion injury in rats.
    Journal of pediatric urology, 2020, Volume: 16, Issue:6

    Topics: Allopurinol; Animals; Chromans; Ischemia; Male; Rats; Reperfusion Injury; Testis

2020
Neuroprotective Effects of Trolox, Human Chorionic Gonadotropin, and Carnosic Acid on Hippocampal Neurodegeneration After Ischemiareperfusion Injury.
    Current stem cell research & therapy, 2019, Volume: 14, Issue:2

    Topics: Abietanes; Animals; Apoptosis; Chorionic Gonadotropin; Chromans; Disease Models, Animal; Hippocampus; Humans; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Reperfusion Injury

2019
Altered pharmacokinetics of cimetidine caused by down-regulation of renal rat organic cation transporter 2 (rOCT2) after liver ischemia-reperfusion injury.
    Drug metabolism and pharmacokinetics, 2013, Volume: 28, Issue:6

    Topics: Animals; Antiporters; Chromans; Cimetidine; Down-Regulation; Liver; Male; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Rats; Rats, Wistar; Reperfusion Injury

2013
Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2015, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Chromans; Disease Models, Animal; Female; Free Radical Scavengers; Gentisates; L-Lactate Dehydrogenase; Liver; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Superoxides

2015
Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Apr-18, Volume: 32, Issue:16

    Topics: Age Factors; Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Benzimidazoles; Blood Flow Velocity; Brain; Brain Mapping; Carbocyanines; Chromans; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Embryo, Mammalian; Female; Flow Cytometry; Hypoxia-Ischemia, Brain; Ionophores; Laser-Doppler Flowmetry; Membrane Potential, Mitochondrial; Metalloporphyrins; Microvessels; Mitochondria; Movement Disorders; Muscle Hypertonia; O Antigens; Pregnancy; Rabbits; Reperfusion Injury; Superoxides; Time Factors; Valinomycin

2012
An antioxidant Trolox restores decreased oral absorption of cyclosporine A after liver ischemia-reperfusion through distinct mechanisms between CYP3A and P-glycoprotein in the small intestine.
    European journal of pharmacology, 2012, Sep-05, Volume: 690, Issue:1-3

    Topics: Administration, Oral; Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Chromans; Cyclosporine; Cytochrome P-450 CYP3A; Gene Expression Regulation, Enzymologic; Glutathione; Intestinal Absorption; Intestine, Small; Liver; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Tissue Distribution

2012
Trolox C ameliorates hepatic drug metabolizing dysfunction after ischemia/reperfusion.
    Archives of pharmacal research, 2002, Volume: 25, Issue:6

    Topics: Animals; Chromans; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Ischemia; Lipid Peroxidation; Liver; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2002
Effect of Trolox on altered vasoregulatory gene expression in hepatic ischemia/reperfusion.
    Archives of pharmacal research, 2004, Volume: 27, Issue:2

    Topics: Alanine Transaminase; Animals; Blood Vessels; Chromans; Cyclooxygenase 2; DNA Primers; Gene Expression Regulation; Glutathione; Isoenzymes; Lipid Peroxidation; Liver; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents; Vasodilator Agents

2004
Effects of Trolox on the activity and gene expression of cytochrome P450 in hepatic ischemia/reperfusion.
    British journal of pharmacology, 2004, Volume: 142, Issue:1

    Topics: Animals; Chromans; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Liver; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2004
Intestinal intraluminal injection of glutamine increases trolox total equivalent antioxidant capacity (TEAC) in hepatic ischemia-reperfusion.
    Acta cirurgica brasileira, 2006, Volume: 21 Suppl 4

    Topics: Animals; Antioxidants; Chromans; Disease Models, Animal; Glutamine; Intestine, Small; Liver; Male; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury

2006
Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats.
    Neurological research, 2007, Volume: 29, Issue:3

    Topics: Animals; Brain Ischemia; Chromans; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Functional Laterality; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors

2007
Renoprotective effect of trolox against ischaemia-reperfusion injury in rats.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:8

    Topics: Animals; Antioxidants; Blood Pressure; Chromans; Disease Models, Animal; Glomerular Filtration Rate; Glutathione; Kidney; Kidney Tubules; Ligation; Male; Malondialdehyde; Natriuresis; Nephrectomy; Rats; Rats, Wistar; Renal Artery; Reperfusion Injury; Time Factors; Urination

2007
Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia.
    Shock (Augusta, Ga.), 1995, Volume: 3, Issue:1

    Topics: Animals; Antibodies, Monoclonal; CD11 Antigens; Chromans; Deferoxamine; Gadolinium; Ischemia; Kupffer Cells; Lipopolysaccharides; Liver; Male; Microcirculation; Multiple Organ Failure; Necrosis; Neutrophils; Rats; Rats, Inbred F344; Reactive Oxygen Species; Reperfusion Injury; Respiratory Burst; Shock, Septic; Superoxides; Time Factors

1995
Propyl gallate as a hepatoprotector in vitro and in vivo.
    Biochemical pharmacology, 1994, Jul-19, Volume: 48, Issue:2

    Topics: Animals; Antioxidants; Chromans; Liver; Male; Propyl Gallate; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1994
Maternal infusion of antioxidants (Trolox and ascorbic acid) protects the fetal heart in rabbit fetal hypoxia.
    Pediatric research, 1996, Volume: 39, Issue:3

    Topics: Animals; Antioxidants; Ascorbic Acid; Bradycardia; Chromans; Creatine Kinase; Female; Fetal Hypoxia; Heart; Pregnancy; Rabbits; Reperfusion Injury; Survival

1996
Vitamin E analogues reduce the incidence of ventricular fibrillations and scavenge free radicals.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Benzopyrans; Chromans; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Phycoerythrin; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Ventricular Fibrillation; Vitamin E

1998
Biphasic mechanism for hypothermic induced loss of protein synthesis in hepatocytes.
    Transplantation, 1999, Jun-15, Volume: 67, Issue:11

    Topics: Adenosine; Allopurinol; Animals; Antioxidants; Chromans; Cryopreservation; Cytosol; Deferoxamine; Dithiothreitol; Glutathione; Insulin; Leucine; Liver; Organ Preservation Solutions; Protein Biosynthesis; Raffinose; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tritium; Vitamin E

1999
Addition of a water-soluble alpha-tocopherol analogue to University of Wisconsin solution improves endothelial viability and decreases lung reperfusion injury.
    The Journal of surgical research, 1999, Volume: 86, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Cattle; Cells, Cultured; Child; Chromans; Endothelium, Vascular; Glutathione; Humans; In Vitro Techniques; Insulin; Ischemia; Lung; Organ Preservation Solutions; Pulmonary Circulation; Raffinose; Rats; Rats, Inbred Lew; Reperfusion Injury; Solubility; Vitamin E

1999
H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene.
    Circulation, 2001, Mar-27, Volume: 103, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Chromans; Creatine Kinase; Disease Models, Animal; Gene Targeting; Heart; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Heterozygote; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Malondialdehyde; Membrane Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardium; Reperfusion Injury; Thiourea

2001
Trolox protects rat hepatocytes against oxyradical damage and the ischemic rat liver from reperfusion injury.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:3

    Topics: Animals; Cells, Cultured; Chromans; Free Radicals; Hypoxanthine; Hypoxanthines; Ischemia; Liver; Liver Diseases; Male; Rats; Rats, Inbred Strains; Reperfusion Injury; Xanthine Oxidase

1991