Page last updated: 2024-08-23

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Parkinson Disease

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with Parkinson Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Amar, M; Brunelle, A; Debortoli, L; Ferrié, L; Figadère, B; Kadar, H; Latini, A; Le Douaron, G; Michel, PP; Raisman-Vozari, R; Schmidt, F; Séon-Méniel, B; Touboul, D1
Aktumsek, A; Alcaro, S; Bagetta, D; Carradori, S; De Monte, C; De Vita, D; Guglielmi, P; Ortuso, F; Petzer, A; Petzer, JP; Secci, D; Zengin, G1
Ahmad, R; Ali, J; Atiq, A; Choe, K; Kang, MH; Khan, A; Kim, MO; Lee, HJ; Park, JS; Rehman, IU; Tahir, M1
Beyrath, J; Boschian, C; Ferraiuolo, L; Lopes, FM; Mortiboys, H; Myszczynska, MA; New, EJ; Schwartzentruber, A; Smeitink, J1
Ehrhart, J; Zeevalk, GD2

Other Studies

6 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Parkinson Disease

ArticleYear
Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Animals; Brain; Cell Culture Techniques; Cells, Cultured; Dopaminergic Neurons; Male; Mice, Inbred C57BL; Molecular Structure; Neuroprotective Agents; Parkinson Disease; Quantitative Structure-Activity Relationship; Quinoxalines; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution

2015
Design, synthesis and biochemical evaluation of novel multi-target inhibitors as potential anti-Parkinson agents.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Acetylcholinesterase; Animals; Antioxidants; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Electrophorus; Horses; Humans; Hydrazones; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Structure-Activity Relationship

2018
Vitamin E Analog Trolox Attenuates MPTP-Induced Parkinson's Disease in Mice, Mitigating Oxidative Stress, Neuroinflammation, and Motor Impairment.
    International journal of molecular sciences, 2023, Jun-09, Volume: 24, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Motor Disorders; Neuroinflammatory Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase; Vitamin E

2023
Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons.
    Scientific reports, 2020, 09-23, Volume: 10, Issue:1

    Topics: Adult; Cell Death; Chromans; Dopaminergic Neurons; Female; Humans; Male; Middle Aged; Mitochondria; Mitophagy; Optical Imaging; Oxidation-Reduction; Parkinson Disease; Ubiquitin-Protein Ligases

2020
Cooperative interaction between ascorbate and glutathione during mitochondrial impairment in mesencephalic cultures.
    Journal of neurochemistry, 2003, Volume: 86, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Chromans; Disulfides; Fluorescent Dyes; Glutathione; Glutathione Disulfide; Malonates; Mesencephalon; Mitochondria; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley

2003
Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures.
    Journal of neurochemistry, 2001, Volume: 77, Issue:6

    Topics: Amitrole; Animals; Antioxidants; Ascorbic Acid; Catalase; Cells, Cultured; Chromans; Energy Metabolism; Enzyme Inhibitors; Glutathione Disulfide; Hydrogen Peroxide; Malonates; Mesencephalon; Neurons; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2001