6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with Necrosis in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alcázar, A; Ayuso, I; Chioua, M; González, MP; Hadjipavlou-Litina, D; Marco-Contelles, J; Monjas, L; Oset-Gasque, MJ; Rodríguez-Franco, MI; Samadi, A; Soriano, E; Sucunza, D | 1 |
| Imai, H; Koumura, T; Matsuoka, M; Miyajima, A; Nakano, H; Nakasone, M; Okochi, H; Sakamoto, T; Tanaka, M; Tsuchiya, Y; Tsurusaki, S; Yuet-Yin Kok, C | 1 |
| Deng, S; Guo, C; He, Z; Lu, Y; Wei, Q; Wen, L; Yang, Y; Yuan, H; Zhu, L | 1 |
| Chu, HW; Kosmider, B; Mason, RJ; Messier, EM | 1 |
| Farrell, GC; Jones, BE; Tapner, MJ; Wu, WM | 1 |
| Chen, K; Liu, Z; Martin, LJ | 1 |
| Farhood, A; Fisher, MA; Jaeschke, H; Liu, P; McGuire, GM; Smith, CW | 1 |
| Gwag, BJ; Noh, JS | 1 |
| Chan, PH; Copin, JC; Li, Y; Reola, L | 1 |
| Gwag, BJ; Jou, I; Park, EC | 1 |
| Gwag, BJ; Joe, E; Kim, EY; Kim, YH; Koh, JY; Sohn, S | 1 |
| Gwag, BJ; Kim, EY; Kim, YH; Koh, JY; Sohn, S | 1 |
| Cantoni, O; Sestili, P; Tommasini, I | 1 |
| Gwag, BJ; Han, KS; Kang, HJ; Kim, EY; Kwon, HJ; Sohn, S; Yoon, WJ | 1 |
| Au, JX; Carey, D; Pristupa, ZB; Sugiyama, H; Wu, J; Wu, TW; Zeng, LH | 1 |
| Birnbaum, PL; Burton, GW; Ingold, KU; Jackowski, G; Li, RK; Madonik, MM; Mickle, DA; Weisel, RD; Wu, TW | 1 |
| Casini, AF; Comporti, M; Pompella, A | 1 |
17 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Necrosis
| Article | Year |
|---|---|
Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood-Brain Barrier; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Edema; Female; Free Radical Scavengers; Hydroxyl Radical; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Necrosis; Neurons; Neuroprotective Agents; Nitric Oxide Donors; Nitrogen Oxides; Oximes; Permeability; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Stereoisomerism; Stroke; Structure-Activity Relationship; Superoxides | 2012 |
Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Chromans; Cytokines; Diet; Ethionine; Ferroptosis; Hepatitis; Hepatocytes; Iron Chelating Agents; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necroptosis; Necrosis; Non-alcoholic Fatty Liver Disease | 2019 |
Zearalenone induces apoptosis and necrosis in porcine granulosa cells via a caspase-3- and caspase-9-dependent mitochondrial signaling pathway.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Caspase 9; Cell Proliferation; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Female; Granulosa Cells; In Situ Nick-End Labeling; Mitochondria; Necrosis; Reactive Oxygen Species; Signal Transduction; Swine; Zearalenone | 2012 |
Human alveolar epithelial cell injury induced by cigarette smoke.
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Apoptosis; Benzimidazoles; Chromans; Epithelial Cells; Humans; In Situ Nick-End Labeling; Lung Diseases; Microscopy, Fluorescence; Necrosis; NF-E2-Related Factor 2; Oxidative Stress; Phenotype; Propidium; Pulmonary Alveoli; Smoking | 2011 |
Toxicity of low dose azathioprine and 6-mercaptopurine in rat hepatocytes. Roles of xanthine oxidase and mitochondrial injury.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Antioxidants; Azathioprine; Cell Differentiation; Cell Survival; Cells, Cultured; Chromans; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; Hepatocytes; Male; Mercaptopurine; Microscopy, Electron; Mitochondria, Liver; Necrosis; Oxidative Stress; Rats; Rats, Wistar; Time Factors; Xanthine Oxidase | 2004 |
Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.
Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Antioxidants; Apoptosis; Caspase 8; Caspases; Chromans; Disease Models, Animal; DNA Damage; DNA Glycosylases; DNA Repair; Enzyme Induction; Fas Ligand Protein; fas Receptor; Humans; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Dehydrogenase; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Point Mutation; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Sciatic Nerve; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Tumor Necrosis Factors; Tumor Suppressor Protein p53 | 2005 |
Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia.
Topics: Animals; Antibodies, Monoclonal; CD11 Antigens; Chromans; Deferoxamine; Gadolinium; Ischemia; Kupffer Cells; Lipopolysaccharides; Liver; Male; Microcirculation; Multiple Organ Failure; Necrosis; Neutrophils; Rats; Rats, Inbred F344; Reactive Oxygen Species; Reperfusion Injury; Respiratory Burst; Shock, Septic; Superoxides; Time Factors | 1995 |
Attenuation of oxidative neuronal necrosis by a dopamine D1 agonist in mouse cortical cell cultures.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antioxidants; Apoptosis; Cells, Cultured; Cerebral Cortex; Chromans; Culture Media, Serum-Free; Dopamine Agonists; Dopamine Antagonists; Mice; Necrosis; Neurons; Neuroprotective Agents; Oxidation-Reduction; Receptors, Dopamine D1; Vitamin E | 1997 |
Trolox and 6,7-dinitroquinoxaline-2,3-dione prevent necrosis but not apoptosis in cultured neurons subjected to oxygen deprivation.
Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Chromans; DNA; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flow Cytometry; Hypoxia, Brain; Lipid Peroxidation; Mice; Necrosis; Neurons; Oxidative Stress; Phosphopyruvate Hydratase; Quinoxalines | 1998 |
Nerve growth factor potentiates the oxidative necrosis of striatal cholinergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholinesterase; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Buthionine Sulfoximine; Cells, Cultured; Chromans; Corpus Striatum; Cycloheximide; Dizocilpine Maleate; Drug Synergism; Fetus; Free Radicals; Iron; Necrosis; Nerve Degeneration; Nerve Growth Factors; Neuroglia; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley | 1998 |
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Chromans; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Dopamine Agonists; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Free Radicals; Hypoglycemic Agents; Insulin; Kainic Acid; Lipid Peroxidation; Mice; Microscopy, Electron; Mitochondrial Swelling; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Oligopeptides; Oxidative Stress; Pregnancy; Zinc | 1999 |
Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals.
Topics: Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Chromans; Cycloheximide; DNA Fragmentation; Free Radicals; In Situ Nick-End Labeling; Iron; L-Lactate Dehydrogenase; Mice; Mice, Inbred ICR; Microscopy, Electron; Necrosis; Neurons; Potassium; Protein Synthesis Inhibitors; Zinc | 1999 |
Peroxynitrite promotes mitochondrial permeability transition-dependent rapid U937 cell necrosis: survivors proliferate with kinetics superimposable on those of untreated cells.
Topics: Antioxidants; Cell Division; Cell Survival; Chromans; Cyclosporine; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Kinetics; Methionine; Mitochondria; Necrosis; Nitrates; Permeability; U937 Cells | 2001 |
1,2-bis(2-Aminophenoxy)ethane-N,N,N',N'-tetraacetic acid induces caspase-mediated apoptosis and reactive oxygen species-mediated necrosis in cultured cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Chelating Agents; Chromans; Cycloheximide; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Egtazic Acid; Fetus; Kinetics; Mice; Mice, Inbred ICR; Necrosis; Neocortex; Neuroglia; Neurons; Neuroprotective Agents; Reactive Oxygen Species; Time Factors | 2001 |
Enhancement in antioxidant-based hepatoprotective activity of Trolox by its conjugation to lactosylphenylpyranoside.
Topics: Animals; Antioxidants; Chromans; Drug Stability; Free Radicals; Glycosides; Liver; Male; Necrosis; Oxygen; Rats; Rats, Inbred Strains; Solubility; Xanthine Oxidase | 1992 |
Myocardial salvage with trolox and ascorbic acid for an acute evolving infarction.
Topics: Animals; Antioxidants; Ascorbic Acid; Benzopyrans; Cells, Cultured; Chromans; Disease Models, Animal; Dogs; Free Radicals; Heart; Hemodynamics; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis | 1989 |
Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chromans; Glutathione; Iodobenzenes; Lipid Peroxides; Liver; Liver Diseases; Male; Maleates; Mice; Necrosis; Proteins; Rats; Rats, Inbred Strains | 1985 |