Page last updated: 2024-08-23

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Innate Inflammatory Response

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with Innate Inflammatory Response in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.70)18.2507
2000's8 (29.63)29.6817
2010's15 (55.56)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Hadjipavlou-Litina, D; Krokidis, M; Magoulas, GE; Papaioannou, D1
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Carotti, A; Hadjipavlou-Litina, D; Litinas, K; Nicolotti, O; Pontiki, E1
Athanassopoulos, CM; Avgoustakis, K; Bariamis, SE; Hadjipavlou-Litina, D; Kontogiorgis, C; Marin, M; Papaioannou, D; Romeo, G; Sindona, G; Tsimali, Z1
Chen, C; Fu, J; Hu, M; Li, X; Shao, S; Shi, G; Wang, D; Wu, S; Zhang, D; Zhang, T; Zhou, Y1
Kourounakis, PN; Papagiouvannis, G; Rekka, EA; Theodosis-Nobelos, P1
Athanasekou, C; Kourounakis, PN; Pantelidou, M; Papagiouvanis, G; Rekka, EA; Theodosis-Nobelos, P1
Aguiar, HQDS; de Cordova, CAS; de Cordova, FM; Medeiros, RCN; Moraes, JO; Pereira, LM; Rodrigues, SDC; Yim Júnior, A1
Beyrath, J; Hankemeier, T; Jiang, X; Pecheritsyna, S; Pennings, B; Renkema, H; Schoeman, JC; Smeitink, J1
Kourounakis, A; Lambrinidis, G; Tzara, A1
Coitinho, AS; de Coelho, DM; Deon, M; Guerreiro, GB; Jacques, CE; Jardim, LB; Marchetti, DP; Mescka, CP; Moura, DJ; Poletto, F; Steffens, L; Vargas, CR; Viario, AG1
Demer, LL; Garcia, J; Iriana, S; Kalajzic, I; Li, X; Lu, J; Rowe, D; Tintut, Y1
Arab, HH; Maghrabi, IA; Omar, HA; Salama, SA; Snapka, RM1
Gruse, J; Hammon, HM; Jawor, P; Kanitz, E; Stefaniak, T; Tuchscherer, A; Weitzel, JM; Wolffram, S1
Engels, M; Grune, T; Horakova, L; Strosova, M; Voss, P1
Chen, TY; Chi, KH; Chien, CL; Lin, WW; Wang, JS1
Chi, CW; Huang, PL; Liu, TY1
Bell, HK; Bloomer, RJ1
Esser, PR; Lademann, J; Martin, SF; Schempp, CM; Simon-Haarhaus, B; Wölfle, U1
Chiu, CS; Deng, JS; Hou, WC; Huang, GJ; Huang, SS; Liao, JC; Lin, WC1
Filipov, NM; Lawrence, DA; Seegal, RF1
Dibarnardi, A; Dumke, CL; Henson, DA; Hosick, PA; Hudson, MH; McAnulty, LS; McAnulty, SR; Milne, GL; Morrow, JD; Nieman, DC; Quindry, JC; Still, L; Triplett, NT; Utter, AC1
Cueto, R; Freed, AN; Pryor, WA1
Arita, S; Maruyama, M; Mullen, Y; Nagai, T; Sakamoto, Y; Smith, CV1
Denno, R; Iwata, S; Kanai, M; Kawada, K; Kawai, Y; Obama, K; Takabayashi, A; Taki, Y1
Baldus, S; Brennan, ML; Castro, L; Eiserich, JP; Freeman, BA; Lusis, AJ; Ma, W; Nauseef, WM; Tousson, A; White, CR; Zhang, C1
Bulger, EM; Garcia, I; Maier, RV1

Trials

1 trial(s) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Innate Inflammatory Response

ArticleYear
Chronic quercetin ingestion and exercise-induced oxidative damage and inflammation.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2008, Volume: 33, Issue:2

    Topics: Adult; Anaerobic Threshold; Antioxidants; Bicycling; C-Reactive Protein; Chromans; Double-Blind Method; Exercise; Ferric Compounds; Heart Rate; Humans; Inflammation; Isoprostanes; Male; Nitrites; Oxidative Stress; Quercetin

2008

Other Studies

26 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Innate Inflammatory Response

ArticleYear
Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:1

    Topics: Acitretin; Amides; Animals; Antioxidants; Edema; Electrons; Esters; Female; Glycine max; Heterocyclic Compounds; Hydrophobic and Hydrophilic Interactions; Inflammation; Lipid Peroxidation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Polyenes; Rats

2010
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Acrylates; Animals; Anti-Inflammatory Agents; Antioxidants; Binding Sites; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Female; Free Radical Scavengers; Glycine max; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Models, Molecular; Protein Conformation; Rats

2011
Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Anti-Inflammatory Agents; Antioxidants; Dose-Response Relationship, Drug; Furocoumarins; Glycine max; Inflammation; Lipid Peroxidation; Lipoxygenase; Molecular Structure; Structure-Activity Relationship

2013
Design, synthesis, and evaluation of isoflavone analogs as multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Apr-15, Volume: 168

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Isoflavones; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Neuroprotective Agents; Receptors, Histamine H3; Structure-Activity Relationship

2019
Active Anti-Inflammatory and Hypolipidemic Derivatives of Lorazepam.
    Molecules (Basel, Switzerland), 2019, Sep-09, Volume: 24, Issue:18

    Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan; Chromans; Humans; Hyperlipidemias; Hypolipidemic Agents; Inflammation; Lipid Peroxidation; Lipoxygenase Inhibitors; Lorazepam; Oxidative Stress; Rats; Thioctic Acid

2019
Design, Synthesis and Study of Nitrogen Monoxide Donors as Potent Hypolipidaemic and Anti-Inflammatory Agents.
    Molecules (Basel, Switzerland), 2019, Dec-19, Volume: 25, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Chromans; Cinnamates; Disease Models, Animal; Esterification; Inflammation; Lipid Peroxidation; Lipoxygenase; Molecular Structure; Nitric Oxide Donors; Rats

2019
Thiamine Deficiency Modulates p38
    Neurochemical research, 2020, Volume: 45, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Cell Survival; Chromans; Dimethyl Sulfoxide; Eating; Heme Oxygenase-1; Inflammation; Male; Membrane Proteins; Mice; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrithiamine; Thiamine Deficiency

2020
Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE
    Scientific reports, 2021, 01-13, Volume: 11, Issue:1

    Topics: Animals; Cells, Cultured; Chromans; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Humans; Inflammation; Interleukin-1beta; Intramolecular Oxidoreductases; Lipopolysaccharides; Mice; Microsomes; Mitochondrial Diseases; Oxidation-Reduction; Prostaglandin-E Synthases; RAW 264.7 Cells

2021
Design of Multifaceted Antioxidants: Shifting towards Anti-Inflammatory and Antihyperlipidemic Activity.
    Molecules (Basel, Switzerland), 2021, Aug-14, Volume: 26, Issue:16

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Atherosclerosis; Chromans; Drug Design; Humans; Hyperlipidemias; Hypolipidemic Agents; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Docking Simulation; Nerve Degeneration; Oxidative Stress; Parabens; Structure-Activity Relationship

2021
Oxidative Imbalance, Nitrative Stress, and Inflammation in C6 Glial Cells Exposed to Hexacosanoic Acid: Protective Effect of N-acetyl-L-cysteine, Trolox, and Rosuvastatin.
    Cellular and molecular neurobiology, 2018, Volume: 38, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Survival; Chromans; Cytoplasmic Vesicles; DNA Damage; Fatty Acids; Inflammation; Interleukin-1beta; Isoprostanes; Neuroglia; Neuroprotective Agents; Nitrates; Nitrites; Nitrosative Stress; Oxidative Stress; Rats; Rosuvastatin Calcium

2018
Roles of parathyroid hormone (PTH) receptor and reactive oxygen species in hyperlipidemia-induced PTH resistance in preosteoblasts.
    Journal of cellular biochemistry, 2014, Volume: 115, Issue:1

    Topics: Animals; Cells, Cultured; Chromans; Female; Green Fluorescent Proteins; Hyperlipidemias; Inflammation; Mice; Mice, Mutant Strains; Mice, Transgenic; Osteoblasts; Osteocytes; Parathyroid Hormone; Reactive Oxygen Species; Receptor, Parathyroid Hormone, Type 1; Receptors, LDL

2014
Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells.
    Inflammation, 2014, Volume: 37, Issue:3

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Line; Cell Proliferation; Chromans; Glutathione; Humans; Hypochlorous Acid; Inflammation; Kidney; Lung; Neutrophils; Nicotine; Oxidation-Reduction; Proliferating Cell Nuclear Antigen

2014
Quercetin Feeding in Newborn Dairy Calves Cannot Compensate Colostrum Deprivation: Study on Metabolic, Antioxidative and Inflammatory Traits.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Administration, Oral; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Antioxidants; Blood Glucose; Body Temperature; C-Reactive Protein; Cattle; Cholesterol; Chromans; Colostrum; F2-Isoprostanes; Feces; Female; Flavonols; Haptoglobins; Hydrocortisone; Immunoglobulins; Inflammation; Lactic Acid; Liver; Milk; Quercetin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tumor Necrosis Factor-alpha

2016
Protective effect of antioxidants against sarcoplasmic reticulum (SR) oxidation by Fenton reaction, however without prevention of Ca-pump activity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:7

    Topics: Animals; Antioxidants; Ascorbic Acid; Carbolines; Chromans; Ferrous Compounds; Flavonoids; Ginkgo biloba; Hydrogen Peroxide; Inflammation; Lipid Peroxidation; Muscle, Skeletal; Oxidation-Reduction; Plant Extracts; Protein Carbonylation; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Swine; Time Factors

2008
Reactive oxygen species are involved in FasL-induced caspase-independent cell death and inflammatory responses.
    Free radical biology & medicine, 2009, Mar-01, Volume: 46, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Line; Chemokine CXCL2; Chromans; Cyclooxygenase 2; Fas Ligand Protein; fas Receptor; Fibroblasts; Gene Expression Regulation; Inflammation; Membrane Potential, Mitochondrial; Mice; Mitochondria; Reactive Oxygen Species; Signal Transduction

2009
Effects of Areca catechu L. containing procyanidins on cyclooxygenase-2 expression in vitro and in vivo.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Areca; Blotting, Western; Carrageenan; Cell Line, Tumor; Chromans; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Male; Nuts; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2010
Impact of serum estradiol on postprandial lipemia, oxidative stress, and inflammation across a single menstrual cycle.
    Gender medicine, 2010, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Antioxidants; Area Under Curve; C-Reactive Protein; Chromans; Dietary Fats; Energy Intake; Estradiol; Female; Follicular Phase; Humans; Hydrogen Peroxide; Hyperlipidemias; Inflammation; Malondialdehyde; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Postprandial Period; Tennessee; Time Factors; Triglycerides

2010
UVB-induced DNA damage, generation of reactive oxygen species, and inflammation are effectively attenuated by the flavonoid luteolin in vitro and in vivo.
    Free radical biology & medicine, 2011, May-01, Volume: 50, Issue:9

    Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cyclooxygenase 2; Cytoprotection; Dinoprostone; DNA Damage; Erythema; Extracellular Signal-Regulated MAP Kinases; Fluoresceins; Gene Expression; Humans; Inflammation; Inhibitory Concentration 50; Keratinocytes; Luteolin; Organ Culture Techniques; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Chemical compositions, anti-inflammatory, antiproliferative and radical-scavenging activities of Actinidia callosa var. ephippioides.
    The American journal of Chinese medicine, 2012, Volume: 40, Issue:5

    Topics: Actinidia; Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Catechin; Cell Line; Cell Proliferation; Chromans; Flavonoids; Free Radical Scavengers; Inflammation; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Phytotherapy; Picrates; Plant Extracts; Plant Stems; Polyphenols

2012
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cytokines; Enzyme Inhibitors; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Manganese Poisoning; Mice; Microglia; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pentoxifylline; Phosphodiesterase Inhibitors; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone

2005
Antioxidant transport modulates peripheral airway reactivity and inflammation during ozone exposure.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:5

    Topics: Airway Resistance; Aldehydes; Animals; Antioxidants; Ascorbic Acid; Biological Transport, Active; Bronchoalveolar Lavage Fluid; Cell Count; Chromans; Dogs; Inflammation; Male; Oxidants, Photochemical; Ozone; Peroxides; Probenecid; Proteins; Respiratory System; Uricosuric Agents

1999
Islet graft primary nonfunction and its prevention.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Chromans; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Graft Survival; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Subrenal Capsule Assay; Transplantation, Homologous; Transplantation, Isogeneic

2000
Nitric oxide induces a decrease in the mitochondrial membrane potential of peripheral blood lymphocytes, especially in natural killer cells.
    Antioxidants & redox signaling, 2000,Winter, Volume: 2, Issue:4

    Topics: Antioxidants; Apoptosis; Chromans; Humans; In Vitro Techniques; Inflammation; Killer Cells, Natural; Lymphocytes; Membrane Potentials; Mitochondria; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Reactive Oxygen Species

2000
Myeloperoxidase, a leukocyte-derived vascular NO oxidase.
    Science (New York, N.Y.), 2002, Jun-28, Volume: 296, Issue:5577

    Topics: Animals; Aorta; Catalysis; Cattle; Cells, Cultured; Chromans; Coculture Techniques; Cyclic GMP; Endothelium, Vascular; Endotoxemia; Humans; Hydrogen Peroxide; Inflammation; Leukocytes; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Mutation; Nitric Oxide; Oxidation-Reduction; Peroxidase; Rats; Rats, Sprague-Dawley; Signal Transduction; Transfection; Tumor Cells, Cultured; Vasodilation

2002
Intracellular antioxidant activity is necessary to modulate the macrophage response to endotoxin.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Coagulation Factors; Butylated Hydroxyanisole; Cells, Cultured; Chromans; Endotoxins; F2-Isoprostanes; Inflammation; Macrophages, Alveolar; Male; Rabbits; Reactive Oxygen Species; Respiratory Distress Syndrome; Signal Transduction; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2002