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6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Inflammation

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with Inflammation in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.70)18.2507
2000's8 (29.63)29.6817
2010's15 (55.56)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Hadjipavlou-Litina, D; Krokidis, M; Magoulas, GE; Papaioannou, D1
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Carotti, A; Hadjipavlou-Litina, D; Litinas, K; Nicolotti, O; Pontiki, E1
Athanassopoulos, CM; Avgoustakis, K; Bariamis, SE; Hadjipavlou-Litina, D; Kontogiorgis, C; Marin, M; Papaioannou, D; Romeo, G; Sindona, G; Tsimali, Z1
Chen, C; Fu, J; Hu, M; Li, X; Shao, S; Shi, G; Wang, D; Wu, S; Zhang, D; Zhang, T; Zhou, Y1
Kourounakis, PN; Papagiouvannis, G; Rekka, EA; Theodosis-Nobelos, P1
Athanasekou, C; Kourounakis, PN; Pantelidou, M; Papagiouvanis, G; Rekka, EA; Theodosis-Nobelos, P1
Aguiar, HQDS; de Cordova, CAS; de Cordova, FM; Medeiros, RCN; Moraes, JO; Pereira, LM; Rodrigues, SDC; Yim Júnior, A1
Beyrath, J; Hankemeier, T; Jiang, X; Pecheritsyna, S; Pennings, B; Renkema, H; Schoeman, JC; Smeitink, J1
Kourounakis, A; Lambrinidis, G; Tzara, A1
Coitinho, AS; de Coelho, DM; Deon, M; Guerreiro, GB; Jacques, CE; Jardim, LB; Marchetti, DP; Mescka, CP; Moura, DJ; Poletto, F; Steffens, L; Vargas, CR; Viario, AG1
Demer, LL; Garcia, J; Iriana, S; Kalajzic, I; Li, X; Lu, J; Rowe, D; Tintut, Y1
Arab, HH; Maghrabi, IA; Omar, HA; Salama, SA; Snapka, RM1
Gruse, J; Hammon, HM; Jawor, P; Kanitz, E; Stefaniak, T; Tuchscherer, A; Weitzel, JM; Wolffram, S1
Engels, M; Grune, T; Horakova, L; Strosova, M; Voss, P1
Chen, TY; Chi, KH; Chien, CL; Lin, WW; Wang, JS1
Chi, CW; Huang, PL; Liu, TY1
Bell, HK; Bloomer, RJ1
Esser, PR; Lademann, J; Martin, SF; Schempp, CM; Simon-Haarhaus, B; Wölfle, U1
Chiu, CS; Deng, JS; Hou, WC; Huang, GJ; Huang, SS; Liao, JC; Lin, WC1
Filipov, NM; Lawrence, DA; Seegal, RF1
Dibarnardi, A; Dumke, CL; Henson, DA; Hosick, PA; Hudson, MH; McAnulty, LS; McAnulty, SR; Milne, GL; Morrow, JD; Nieman, DC; Quindry, JC; Still, L; Triplett, NT; Utter, AC1
Cueto, R; Freed, AN; Pryor, WA1
Arita, S; Maruyama, M; Mullen, Y; Nagai, T; Sakamoto, Y; Smith, CV1
Denno, R; Iwata, S; Kanai, M; Kawada, K; Kawai, Y; Obama, K; Takabayashi, A; Taki, Y1
Baldus, S; Brennan, ML; Castro, L; Eiserich, JP; Freeman, BA; Lusis, AJ; Ma, W; Nauseef, WM; Tousson, A; White, CR; Zhang, C1
Bulger, EM; Garcia, I; Maier, RV1

Trials

1 trial(s) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Inflammation

ArticleYear
Chronic quercetin ingestion and exercise-induced oxidative damage and inflammation.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2008, Volume: 33, Issue:2

    Topics: Adult; Anaerobic Threshold; Antioxidants; Bicycling; C-Reactive Protein; Chromans; Double-Blind Method; Exercise; Ferric Compounds; Heart Rate; Humans; Inflammation; Isoprostanes; Male; Nitrites; Oxidative Stress; Quercetin

2008

Other Studies

26 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Inflammation

ArticleYear
Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:1

    Topics: Acitretin; Amides; Animals; Antioxidants; Edema; Electrons; Esters; Female; Glycine max; Heterocyclic Compounds; Hydrophobic and Hydrophilic Interactions; Inflammation; Lipid Peroxidation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Polyenes; Rats

2010
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Acrylates; Animals; Anti-Inflammatory Agents; Antioxidants; Binding Sites; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Female; Free Radical Scavengers; Glycine max; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Models, Molecular; Protein Conformation; Rats

2011
Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Anti-Inflammatory Agents; Antioxidants; Dose-Response Relationship, Drug; Furocoumarins; Glycine max; Inflammation; Lipid Peroxidation; Lipoxygenase; Molecular Structure; Structure-Activity Relationship

2013
Design, synthesis, and evaluation of isoflavone analogs as multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Apr-15, Volume: 168

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Isoflavones; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Neuroprotective Agents; Receptors, Histamine H3; Structure-Activity Relationship

2019
Active Anti-Inflammatory and Hypolipidemic Derivatives of Lorazepam.
    Molecules (Basel, Switzerland), 2019, Sep-09, Volume: 24, Issue:18

    Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan; Chromans; Humans; Hyperlipidemias; Hypolipidemic Agents; Inflammation; Lipid Peroxidation; Lipoxygenase Inhibitors; Lorazepam; Oxidative Stress; Rats; Thioctic Acid

2019
Design, Synthesis and Study of Nitrogen Monoxide Donors as Potent Hypolipidaemic and Anti-Inflammatory Agents.
    Molecules (Basel, Switzerland), 2019, Dec-19, Volume: 25, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Chromans; Cinnamates; Disease Models, Animal; Esterification; Inflammation; Lipid Peroxidation; Lipoxygenase; Molecular Structure; Nitric Oxide Donors; Rats

2019
Thiamine Deficiency Modulates p38
    Neurochemical research, 2020, Volume: 45, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Cell Survival; Chromans; Dimethyl Sulfoxide; Eating; Heme Oxygenase-1; Inflammation; Male; Membrane Proteins; Mice; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrithiamine; Thiamine Deficiency

2020
Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE
    Scientific reports, 2021, 01-13, Volume: 11, Issue:1

    Topics: Animals; Cells, Cultured; Chromans; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Humans; Inflammation; Interleukin-1beta; Intramolecular Oxidoreductases; Lipopolysaccharides; Mice; Microsomes; Mitochondrial Diseases; Oxidation-Reduction; Prostaglandin-E Synthases; RAW 264.7 Cells

2021
Design of Multifaceted Antioxidants: Shifting towards Anti-Inflammatory and Antihyperlipidemic Activity.
    Molecules (Basel, Switzerland), 2021, Aug-14, Volume: 26, Issue:16

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Atherosclerosis; Chromans; Drug Design; Humans; Hyperlipidemias; Hypolipidemic Agents; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Docking Simulation; Nerve Degeneration; Oxidative Stress; Parabens; Structure-Activity Relationship

2021
Oxidative Imbalance, Nitrative Stress, and Inflammation in C6 Glial Cells Exposed to Hexacosanoic Acid: Protective Effect of N-acetyl-L-cysteine, Trolox, and Rosuvastatin.
    Cellular and molecular neurobiology, 2018, Volume: 38, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Survival; Chromans; Cytoplasmic Vesicles; DNA Damage; Fatty Acids; Inflammation; Interleukin-1beta; Isoprostanes; Neuroglia; Neuroprotective Agents; Nitrates; Nitrites; Nitrosative Stress; Oxidative Stress; Rats; Rosuvastatin Calcium

2018
Roles of parathyroid hormone (PTH) receptor and reactive oxygen species in hyperlipidemia-induced PTH resistance in preosteoblasts.
    Journal of cellular biochemistry, 2014, Volume: 115, Issue:1

    Topics: Animals; Cells, Cultured; Chromans; Female; Green Fluorescent Proteins; Hyperlipidemias; Inflammation; Mice; Mice, Mutant Strains; Mice, Transgenic; Osteoblasts; Osteocytes; Parathyroid Hormone; Reactive Oxygen Species; Receptor, Parathyroid Hormone, Type 1; Receptors, LDL

2014
Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells.
    Inflammation, 2014, Volume: 37, Issue:3

    Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Cell Line; Cell Proliferation; Chromans; Glutathione; Humans; Hypochlorous Acid; Inflammation; Kidney; Lung; Neutrophils; Nicotine; Oxidation-Reduction; Proliferating Cell Nuclear Antigen

2014
Quercetin Feeding in Newborn Dairy Calves Cannot Compensate Colostrum Deprivation: Study on Metabolic, Antioxidative and Inflammatory Traits.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Administration, Oral; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Antioxidants; Blood Glucose; Body Temperature; C-Reactive Protein; Cattle; Cholesterol; Chromans; Colostrum; F2-Isoprostanes; Feces; Female; Flavonols; Haptoglobins; Hydrocortisone; Immunoglobulins; Inflammation; Lactic Acid; Liver; Milk; Quercetin; Thiobarbituric Acid Reactive Substances; Triglycerides; Tumor Necrosis Factor-alpha

2016
Protective effect of antioxidants against sarcoplasmic reticulum (SR) oxidation by Fenton reaction, however without prevention of Ca-pump activity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:7

    Topics: Animals; Antioxidants; Ascorbic Acid; Carbolines; Chromans; Ferrous Compounds; Flavonoids; Ginkgo biloba; Hydrogen Peroxide; Inflammation; Lipid Peroxidation; Muscle, Skeletal; Oxidation-Reduction; Plant Extracts; Protein Carbonylation; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Swine; Time Factors

2008
Reactive oxygen species are involved in FasL-induced caspase-independent cell death and inflammatory responses.
    Free radical biology & medicine, 2009, Mar-01, Volume: 46, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Line; Chemokine CXCL2; Chromans; Cyclooxygenase 2; Fas Ligand Protein; fas Receptor; Fibroblasts; Gene Expression Regulation; Inflammation; Membrane Potential, Mitochondrial; Mice; Mitochondria; Reactive Oxygen Species; Signal Transduction

2009
Effects of Areca catechu L. containing procyanidins on cyclooxygenase-2 expression in vitro and in vivo.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Areca; Blotting, Western; Carrageenan; Cell Line, Tumor; Chromans; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Male; Nuts; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2010
Impact of serum estradiol on postprandial lipemia, oxidative stress, and inflammation across a single menstrual cycle.
    Gender medicine, 2010, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Antioxidants; Area Under Curve; C-Reactive Protein; Chromans; Dietary Fats; Energy Intake; Estradiol; Female; Follicular Phase; Humans; Hydrogen Peroxide; Hyperlipidemias; Inflammation; Malondialdehyde; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Postprandial Period; Tennessee; Time Factors; Triglycerides

2010
UVB-induced DNA damage, generation of reactive oxygen species, and inflammation are effectively attenuated by the flavonoid luteolin in vitro and in vivo.
    Free radical biology & medicine, 2011, May-01, Volume: 50, Issue:9

    Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cyclooxygenase 2; Cytoprotection; Dinoprostone; DNA Damage; Erythema; Extracellular Signal-Regulated MAP Kinases; Fluoresceins; Gene Expression; Humans; Inflammation; Inhibitory Concentration 50; Keratinocytes; Luteolin; Organ Culture Techniques; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Chemical compositions, anti-inflammatory, antiproliferative and radical-scavenging activities of Actinidia callosa var. ephippioides.
    The American journal of Chinese medicine, 2012, Volume: 40, Issue:5

    Topics: Actinidia; Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Catechin; Cell Line; Cell Proliferation; Chromans; Flavonoids; Free Radical Scavengers; Inflammation; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Phytotherapy; Picrates; Plant Extracts; Plant Stems; Polyphenols

2012
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cells, Cultured; Chromans; Cytokines; Enzyme Inhibitors; Inflammation; L-Lactate Dehydrogenase; Lipopolysaccharides; Manganese Poisoning; Mice; Microglia; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pentoxifylline; Phosphodiesterase Inhibitors; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone

2005
Antioxidant transport modulates peripheral airway reactivity and inflammation during ozone exposure.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:5

    Topics: Airway Resistance; Aldehydes; Animals; Antioxidants; Ascorbic Acid; Biological Transport, Active; Bronchoalveolar Lavage Fluid; Cell Count; Chromans; Dogs; Inflammation; Male; Oxidants, Photochemical; Ozone; Peroxides; Probenecid; Proteins; Respiratory System; Uricosuric Agents

1999
Islet graft primary nonfunction and its prevention.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Chromans; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Graft Survival; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Subrenal Capsule Assay; Transplantation, Homologous; Transplantation, Isogeneic

2000
Nitric oxide induces a decrease in the mitochondrial membrane potential of peripheral blood lymphocytes, especially in natural killer cells.
    Antioxidants & redox signaling, 2000,Winter, Volume: 2, Issue:4

    Topics: Antioxidants; Apoptosis; Chromans; Humans; In Vitro Techniques; Inflammation; Killer Cells, Natural; Lymphocytes; Membrane Potentials; Mitochondria; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Reactive Oxygen Species

2000
Myeloperoxidase, a leukocyte-derived vascular NO oxidase.
    Science (New York, N.Y.), 2002, Jun-28, Volume: 296, Issue:5577

    Topics: Animals; Aorta; Catalysis; Cattle; Cells, Cultured; Chromans; Coculture Techniques; Cyclic GMP; Endothelium, Vascular; Endotoxemia; Humans; Hydrogen Peroxide; Inflammation; Leukocytes; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Mutation; Nitric Oxide; Oxidation-Reduction; Peroxidase; Rats; Rats, Sprague-Dawley; Signal Transduction; Transfection; Tumor Cells, Cultured; Vasodilation

2002
Intracellular antioxidant activity is necessary to modulate the macrophage response to endotoxin.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood Coagulation Factors; Butylated Hydroxyanisole; Cells, Cultured; Chromans; Endotoxins; F2-Isoprostanes; Inflammation; Macrophages, Alveolar; Male; Rabbits; Reactive Oxygen Species; Respiratory Distress Syndrome; Signal Transduction; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2002