Compounds > 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
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6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Disease Models, Animal

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with Disease Models, Animal in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.44)18.7374
1990's4 (9.76)18.2507
2000's14 (34.15)29.6817
2010's18 (43.90)24.3611
2020's4 (9.76)2.80

Authors

AuthorsStudies
Juskova, M; Milackova, I; Snirc, V; Stefek, M; Triantos, N; Tsantili-Kakoulidou, A1
Choi, Y; Gu, J; Hwang, S; Ju, C; Kim, C; Kim, M; Kim, WK; Kwon, J; Lee, K; Oh, YK; Song, S1
Aguilar-Suárez, R; Correa-Basurto, J; Galindo-Sevilla, N; Hernández-Luis, F; Márquez-Navarro, A; Mendoza-Martínez, C; Montero-Cortes, MD; Nieto-Meneses, R; Nogueda-Torres, B; Rodriguez-Lezama, A; Rojas-Rojas, Á; Suárez-Contreras, E1
Jin, C; Jung, SY; Kim, HJ; Kim, NJ; Kwon, BJ; Lee, YH; Lee, YS; Yoo, H1
da Silva Aguiar, HQ; de Araújo, SS; de Cordova, CAS; de Cordova, FM; Gomes, KC; Lima, FWB1
Ahmad, R; Ali, J; Atiq, A; Choe, K; Kang, MH; Khan, A; Kim, MO; Lee, HJ; Park, JS; Rehman, IU; Tahir, M1
Athanasekou, C; Kourounakis, PN; Pantelidou, M; Papagiouvanis, G; Rekka, EA; Theodosis-Nobelos, P1
Bakker, D; Hollmann, MW; Nederlof, R; Renkema, H; Smeitink, JAM; Weber, NC; Xiao, Y; Yim, K; Zhang, H; Zuurbier, CJ1
Beyrath, J; de Vries, BBA; Hoen, PAC'; Hogeweg, M; Klein Gunnewiek, TM; Kozicz, T; Nadif Kasri, N; Pelgrim, I; Renkema, H; Schoenmaker, C; Smeitink, J; Verboven, AHA1
Adlband, M; Bajoovand, S; Ketabchi, F; Mashghoolozekr, E; Naseh, M; Nekooeian, AA1
Ishida, Y; Janprasit, J; Matsuoka, Y; Morales, NP; Okamoto, Y; Tada, A; Yamada, KI; Yamato, M1
Bochenek, ML; Gogiraju, R; Hubert, A; Jäger, M; Münzel, T; Schäfer, K1
Alizadeh, A; Amini, N; Babahajian, A; Entezari, M; Golab, F; Haramshahi, SMA; Katebi, M; Rasoolijazi, H; Sarveazad, A; Soleimani, M; Vahabzadeh, G1
Dou, QP; Fregona, D; Nardon, C; Schmitt, SM; Yang, H; Zuo, J1
Arab, HA; Cheung, K; Hickman, PE; Kadkhodaee, M; Potter, JM; Roberts, MS; Walker, NI1
Akula, MK; Akyürek, LM; Bergo, MO; Dalin, MG; Ibrahim, MX; Karlsson, C; Le Gal, K; Lindahl, P; Nilsson, J; Sayin, VI; Wiel, C1
Sahach, VF; Talanov, SA1
Bacskai, BJ; Borrelli, LA; Garcia-Alloza, M; Hyman, BT1
Fan, Z; Ke, ZJ; Li, W; Luo, J; Sun, A; Yang, G; Zhang, Q1
Shiba, T; Utsumi, H; Watanabe, T; Yamada, K; Yamato, M1
Acar, A; Akil, E; Alp, H; Evliyaoglu, O; Inal, A; Kibrisli, E; Tasdemir, N; Unan, F1
Batinic-Haberle, I; Derrick, M; Drobyshevsky, A; Du, H; Luo, K; Prasad, PV; Tan, S; Vasquez-Vivar, J; Yu, L1
Ho, WK; Hong, HS; Kim, KR; Lee, SH; Mook-Jung, I; Ryu, SY; Son, S1
Aguiar, AS; Aschner, M; Cordova, FM; Erikson, KM; Farina, M; Gonçalves, FM; Leal, RB; Lopes, MW; Lopes, SC; Pedro, DZ; Peres, TV; Pilati, C; Prediger, RD1
Nakashima, T; Teranishi, MA1
Braum, CA; Bridi, R; Dutra-Filho, CS; Latini, A; Lissi, E; Moacir, W; Zorzi, GK1
Chen, K; Liu, Z; Martin, LJ1
Chemtob, S; Dembinska, O; Dorfman, AL; Lachapelle, P1
Aguilar-Nascimento, JE; Dias, CC; Marques, NR; Percário, S; Salomão, AB; Sano, V1
Kaundal, RK; Sharma, SS1
Lumlertgul, D; Thamprasert, K; Wongmekiat, O1
Maruyama, J; Miller, JM; Ulfendahl, M1
Jin, XQ; Long, F; Qi, HH; Wang, Y; Zhou, X1
Bellows, SD; Hale, SL; Kay, GL; Kloner, RA; Simkhovich, BZ1
Daughters, K; Gassel, A; Waxman, K; Zommer, S1
Bullard, LE; Penn, JS; Tolman, BL1
Bezdetnaya, LN; Brault, D; Guillemin, F; Melnikova, VO; Potapenko, AY1
Alam, J; Das, DK; Ho, YS; Maulik, N; Yoshida, T1
Bauer, I; Bauer, M; Pannen, BH; Paxian, M; Rensing, H; Rickauer, A; Schmeck, J; Schönhofen, S1
Kayser, E; Strubelt, O; Younes, M1
Birnbaum, PL; Burton, GW; Ingold, KU; Jackowski, G; Li, RK; Madonik, MM; Mickle, DA; Weisel, RD; Wu, TW1

Other Studies

41 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Disease Models, Animal

ArticleYear
(2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature.
    Bioorganic & medicinal chemistry, 2011, Dec-01, Volume: 19, Issue:23

    Topics: Acetates; Aldehyde Reductase; Animals; Antioxidants; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Male; Rats; Rats, Wistar; Sorbitol

2011
Discovery of novel (1S)-(-)-verbenone derivatives with anti-oxidant and anti-ischemic effects.
    Bioorganic & medicinal chemistry letters, 2013, Oct-01, Volume: 23, Issue:19

    Topics: Animals; Antioxidants; Bicyclic Monoterpenes; Cells, Cultured; Disease Models, Animal; Drug Discovery; Ischemia; N-Methylaspartate; Neurons; Neuroprotective Agents; Oxidative Stress; Terpenes

2013
Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents.
    European journal of medicinal chemistry, 2015, Volume: 96

    Topics: Administration, Oral; Animals; Antimalarials; Antiprotozoal Agents; Chlorocebus aethiops; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Leishmania major; Malaria; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium vivax; Quinazolines; Structure-Activity Relationship; Trypanosoma cruzi; Vero Cells

2015
Synthesis of (2-amino)ethyl derivatives of quercetin 3-O-methyl ether and their antioxidant and neuroprotective effects.
    Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15

    Topics: Animals; Antioxidants; Brain; Disease Models, Animal; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Neuroprotective Agents; Quercetin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Structure-Activity Relationship

2015
Thiamine deficiency and recovery: impact of recurrent episodes and beneficial effect of treatment with Trolox and dimethyl sulfoxide.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Chromans; Dimethyl Sulfoxide; Disease Models, Animal; Locomotion; Male; Mice; Recurrence; Spatial Memory; Thiamine; Thiamine Deficiency

2021
Vitamin E Analog Trolox Attenuates MPTP-Induced Parkinson's Disease in Mice, Mitigating Oxidative Stress, Neuroinflammation, and Motor Impairment.
    International journal of molecular sciences, 2023, Jun-09, Volume: 24, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Motor Disorders; Neuroinflammatory Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase; Vitamin E

2023
Design, Synthesis and Study of Nitrogen Monoxide Donors as Potent Hypolipidaemic and Anti-Inflammatory Agents.
    Molecules (Basel, Switzerland), 2019, Dec-19, Volume: 25, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Chromans; Cinnamates; Disease Models, Animal; Esterification; Inflammation; Lipid Peroxidation; Lipoxygenase; Molecular Structure; Nitric Oxide Donors; Rats

2019
The Redox Modulating Sonlicromanol Active Metabolite KH176m and the Antioxidant MPG Protect Against Short-Duration Cardiac Ischemia-Reperfusion Injury.
    Cardiovascular drugs and therapy, 2021, Volume: 35, Issue:4

    Topics: Aldehydes; Animals; Antioxidants; Chromans; Disease Models, Animal; Mice; Myocardial Reperfusion Injury; Oxidation-Reduction; Oxidative Stress; Time-to-Treatment; Tiopronin; Treatment Outcome

2021
Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m.3243A>G heteroplasmy in iPSC-derived neurons.
    Stem cell reports, 2021, 09-14, Volume: 16, Issue:9

    Topics: Animals; Astrocytes; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Chromans; Disease Models, Animal; DNA, Mitochondrial; Gene Expression Profiling; Gene Expression Regulation; Genetic Predisposition to Disease; Heteroplasmy; Humans; Induced Pluripotent Stem Cells; Mitochondrial Encephalomyopathies; Neurons; Phenotype; Rats; RNA, Transfer, Leu; Transcriptome

2021
Right ventricular pressure elevated in one-kidney, one clip Goldblatt hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:4

    Topics: Animals; Antioxidants; Arterial Pressure; Chromans; Disease Models, Animal; Heart Ventricles; Hypertension, Renovascular; Hypoxia; Kidney; Male; Rats; Rats, Sprague-Dawley; Systole; Ventricular Pressure

2017
Detection and inhibition of lipid-derived radicals in low-density lipoprotein.
    Free radical biology & medicine, 2017, Volume: 113

    Topics: 4-Chloro-7-nitrobenzofurazan; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chromans; Cyclic N-Oxides; Deferoxamine; Disease Models, Animal; Fluorescent Dyes; Free Radicals; Humans; Iron; Iron Overload; Lipid Peroxidation; Lipoproteins, LDL; Liver; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Spectrometry, Fluorescence

2017
Inducible Knockdown of Endothelial Protein Tyrosine Phosphatase-1B Promotes Neointima Formation in Obese Mice by Enhancing Endothelial Senescence.
    Antioxidants & redox signaling, 2019, 03-01, Volume: 30, Issue:7

    Topics: Animals; Apoptosis; Cell Line; Chlorides; Chromans; Disease Models, Animal; Endothelial Cells; Ferric Compounds; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Obese; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Re-Epithelialization; Tamoxifen; Vascular System Injuries; Wound Healing

2019
Neuroprotective Effects of Trolox, Human Chorionic Gonadotropin, and Carnosic Acid on Hippocampal Neurodegeneration After Ischemiareperfusion Injury.
    Current stem cell research & therapy, 2019, Volume: 14, Issue:2

    Topics: Abietanes; Animals; Apoptosis; Chorionic Gonadotropin; Chromans; Disease Models, Animal; Hippocampus; Humans; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Reperfusion Injury

2019
Gold(III)-dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy: preclinical studies against human breast neoplasia.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromans; Cisplatin; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Female; Free Radical Scavengers; Humans; Mice; Molecular Structure; Molecular Targeted Therapy; Organogold Compounds; Peptidomimetics; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Thiocarbamates; Tumor Burden; Xenograft Model Antitumor Assays

2014
Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2015, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Chromans; Disease Models, Animal; Female; Free Radical Scavengers; Gentisates; L-Lactate Dehydrogenase; Liver; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Superoxides

2015
Antioxidants can increase melanoma metastasis in mice.
    Science translational medicine, 2015, Oct-07, Volume: 7, Issue:308

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Tumor; Chromans; Dietary Supplements; Disease Models, Animal; Glutathione; Humans; Male; Melanoma; Mice; Neoplasm Metastasis

2015
[Antioxidants prevent experimental hemiparkinsonism in rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2008, Volume: 54, Issue:4

    Topics: Animals; Antioxidants; Behavior, Animal; Chromans; Disease Models, Animal; Dopamine; Male; Melatonin; Neurons; Oxidative Stress; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Inbred WKY; Substantia Nigra; Ubiquinone

2008
Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice.
    Neurobiology of aging, 2010, Volume: 31, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Chromans; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Ginkgo biloba; Mice; Mice, Transgenic; Oxidative Stress; Plant Extracts; Plaque, Amyloid; Presenilin-1; Time Factors

2010
Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides.
    Neurobiology of aging, 2011, Volume: 32, Issue:1

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Antioxidants; Aspartic Acid Endopeptidases; Brain; Cell Death; Cell Line, Tumor; Chromans; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Neuroblastoma; Peptide Fragments; Pyrithiamine; Reactive Oxygen Species; Thiamine; Thiamine Deficiency; Time Factors

2011
Separable detection of lipophilic- and hydrophilic-phase free radicals from the ESR spectrum of nitroxyl radical in transient MCAO mice.
    Free radical research, 2009, Volume: 43, Issue:9

    Topics: Animals; Antioxidants; Brain; Chromans; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Mice; Nitrogen Oxides; Octanols; Pyrrolidines; Solvents; Spin Labels; Time Factors; Water

2009
Oxidative damage is ameliorated by curcumin treatment in brain and sciatic nerve of diabetic rats.
    The International journal of neuroscience, 2012, Volume: 122, Issue:7

    Topics: Animals; Brain; Chromans; Curcumin; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve

2012
Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Apr-18, Volume: 32, Issue:16

    Topics: Age Factors; Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Benzimidazoles; Blood Flow Velocity; Brain; Brain Mapping; Carbocyanines; Chromans; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Embryo, Mammalian; Female; Flow Cytometry; Hypoxia-Ischemia, Brain; Ionophores; Laser-Doppler Flowmetry; Membrane Potential, Mitochondrial; Metalloporphyrins; Microvessels; Mitochondria; Movement Disorders; Muscle Hypertonia; O Antigens; Pregnancy; Rabbits; Reperfusion Injury; Superoxides; Time Factors; Valinomycin

2012
Impaired short-term plasticity in mossy fiber synapses caused by mitochondrial dysfunction of dentate granule cells is the earliest synaptic deficit in a mouse model of Alzheimer's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Apr-25, Volume: 32, Issue:17

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Genetically Modified; Antioxidants; Biophysics; Calcium; Chromans; Dentate Gyrus; Disease Models, Animal; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mossy Fibers, Hippocampal; Mutation; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Peptide Fragments; Plasma Membrane Calcium-Transporting ATPases; Reactive Oxygen Species; Ruthenium Compounds; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Synaptic Transmission

2012
Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox.
    Archives of toxicology, 2013, Volume: 87, Issue:7

    Topics: Age Factors; Animals; Animals, Newborn; Antioxidants; Basal Ganglia; Behavior, Animal; Caspases; Chromans; Disease Models, Animal; Enzyme Activation; Female; Male; Manganese Poisoning; Motor Activity; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Rotarod Performance Test; Signal Transduction

2013
Effects of trolox, locally applied on round windows, on cisplatin-induced ototoxicity in guinea pigs.
    International journal of pediatric otorhinolaryngology, 2003, Volume: 67, Issue:2

    Topics: Administration, Topical; Analysis of Variance; Animals; Antioxidants; Auditory Threshold; Chromans; Cisplatin; Disease Models, Animal; Drug Interactions; Ear, Middle; Evoked Potentials, Auditory, Brain Stem; Female; Guinea Pigs; Hearing Loss, Sensorineural; Probability; Random Allocation; Reference Values; Risk Assessment; Round Window, Ear; Sensitivity and Specificity; Treatment Outcome

2003
Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats.
    Free radical research, 2005, Volume: 39, Issue:1

    Topics: Animals; Antioxidants; Brain; Catalase; Cerebral Cortex; Chromans; Disease Models, Animal; Enzyme Inhibitors; Fluoresceins; Free Radicals; Glutathione; Glutathione Peroxidase; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Mitochondria; Neurons; NG-Nitroarginine Methyl Ester; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Valine

2005
Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jul-06, Volume: 25, Issue:27

    Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Antioxidants; Apoptosis; Caspase 8; Caspases; Chromans; Disease Models, Animal; DNA Damage; DNA Glycosylases; DNA Repair; Enzyme Induction; Fas Ligand Protein; fas Receptor; Humans; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Dehydrogenase; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Point Mutation; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Sciatic Nerve; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Tumor Necrosis Factors; Tumor Suppressor Protein p53

2005
Structural and functional consequences of trolox C treatment in the rat model of postnatal hyperoxia.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Chromans; Disease Models, Animal; Electroretinography; Humans; Hyperoxia; Infant, Newborn; Oxygen; Rats; Rats, Sprague-Dawley; Retina; Retinopathy of Prematurity

2006
Intestinal intraluminal injection of glutamine increases trolox total equivalent antioxidant capacity (TEAC) in hepatic ischemia-reperfusion.
    Acta cirurgica brasileira, 2006, Volume: 21 Suppl 4

    Topics: Animals; Antioxidants; Chromans; Disease Models, Animal; Glutamine; Intestine, Small; Liver; Male; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury

2006
Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats.
    Neurological research, 2007, Volume: 29, Issue:3

    Topics: Animals; Brain Ischemia; Chromans; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Functional Laterality; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors

2007
Renoprotective effect of trolox against ischaemia-reperfusion injury in rats.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:8

    Topics: Animals; Antioxidants; Blood Pressure; Chromans; Disease Models, Animal; Glomerular Filtration Rate; Glutathione; Kidney; Kidney Tubules; Ligation; Male; Malondialdehyde; Natriuresis; Nephrectomy; Rats; Rats, Wistar; Renal Artery; Reperfusion Injury; Time Factors; Urination

2007
Glial cell line-derived neurotrophic factor and antioxidants preserve the electrical responsiveness of the spiral ganglion neurons after experimentally induced deafness.
    Neurobiology of disease, 2008, Volume: 29, Issue:1

    Topics: Acoustic Stimulation; Animals; Antioxidants; Ascorbic Acid; Auditory Threshold; Chromans; Deafness; Disease Models, Animal; Dose-Response Relationship, Radiation; Drug Administration Routes; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Glial Cell Line-Derived Neurotrophic Factor; Guinea Pigs; Neurons; Spiral Ganglion; Statistics, Nonparametric

2008
Rapid non-genomic effects of glucocorticoids on oxidative stress in a guinea pig model of asthma.
    Respirology (Carlton, Vic.), 2008, Volume: 13, Issue:2

    Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage; Budesonide; Chromans; Disease Models, Animal; Glucocorticoids; Guinea Pigs; Male; Oxidative Stress; Superoxide Dismutase; Superoxides

2008
Do antioxidant vitamins reduce infarct size following acute myocardial ischemia/reperfusion?
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Blood Pressure; Chromans; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Heart Rate; Hydrogen-Ion Concentration; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Rabbits; Random Allocation; Staining and Labeling; Tetrazolium Salts; Vitamin E

1995
Anti-oxidant treatment for shock: vitamin E but not vitamin C improves survival.
    The American surgeon, 1996, Volume: 62, Issue:10

    Topics: Animals; Antioxidants; Ascorbic Acid; Blood Pressure; Chromans; Disease Models, Animal; Fluid Therapy; Leukocyte Adherence Inhibition Test; Leukocytes; Prospective Studies; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Vitamin E

1996
Effect of a water-soluble vitamin E analog, trolox C, on retinal vascular development in an animal model of retinopathy of prematurity.
    Free radical biology & medicine, 1997, Volume: 22, Issue:6

    Topics: Animals; Animals, Newborn; Antioxidants; Capillaries; Chromans; Dextrans; Disease Models, Animal; Fluorescein; Fluorescein-5-isothiocyanate; Fluoresceins; Humans; Infant, Newborn; Injections, Intraperitoneal; Ink; Oxygen; Rats; Rats, Sprague-Dawley; Retina; Retinopathy of Prematurity

1997
Enhancement of meta-tetrahydroxyphenylchlorin-sensitized photodynamic treatment on human tumor xenografts using a water-soluble vitamin E analogue, Trolox.
    International journal of cancer, 2000, Dec-01, Volume: 88, Issue:5

    Topics: Animals; Antineoplastic Agents; Antioxidants; Chromans; Disease Models, Animal; Drug Interactions; Female; HT29 Cells; Humans; Mesoporphyrins; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen; Photochemotherapy; Photosensitizing Agents; Transplantation, Heterologous

2000
H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene.
    Circulation, 2001, Mar-27, Volume: 103, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Chromans; Creatine Kinase; Disease Models, Animal; Gene Targeting; Heart; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Heterozygote; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Malondialdehyde; Membrane Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardium; Reperfusion Injury; Thiourea

2001
Kupffer cells and neutrophils as paracrine regulators of the heme oxygenase-1 gene in hepatocytes after hemorrhagic shock.
    Shock (Augusta, Ga.), 2001, Volume: 15, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Pressure; Cells, Cultured; Chromans; Clodronic Acid; Deferoxamine; Disease Models, Animal; Gadolinium; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; Kupffer Cells; Male; Neutrophils; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Time Factors; Vinblastine

2001
Effect of antioxidants on hypoxia/reoxygenation-induced injury in isolated perfused rat liver.
    Pharmacology & toxicology, 1992, Volume: 71, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Bile; Cell Hypoxia; Chromans; Disease Models, Animal; Glutamate Dehydrogenase; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Oxygen Consumption; Propyl Gallate; Rats; Rats, Wistar

1992
Myocardial salvage with trolox and ascorbic acid for an acute evolving infarction.
    The Annals of thoracic surgery, 1989, Volume: 47, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Benzopyrans; Cells, Cultured; Chromans; Disease Models, Animal; Dogs; Free Radicals; Heart; Hemodynamics; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis

1989